LyrArc Article Gist
The WSJ provides an excellent guide to working at home, how to overcome the struggles and get some of the benefits from working at home.

A large part of the struggles in working from home is not being able to unplug, and working like you are in an office. Working from office is different because of meetings and office distractions, and one gets less done, maybe 4 hours of decent work in a workday. So that in solo work one would say work 5 hours and accomplish what one would have done in 8 hours at the office.  At home consistently working 5 or 6 hours at a stretch can get a person exhausted and isolated.  Don't look at the clock for it to say 5 pm. Take breaks early, if one reaches ones limit or gets restless it is time to take an extended break or get outside for a walk, or do some stretches, yoga, or something else.

Loneliness is another part of the struggles. Important to setup some video calls to make sure you get human interaction. Get some chance to refresh and talk to humans, get some interaction. 

Leave stuff such as clearing inbox and less brainy tasks for the evening. Set top 3 priorities for the day or week so you have an idea of progress in a larger task. Time theming is a way to set aside certain days or time periods to get specific things done.

Staying physically fit and mentally rejuvenated is the big challenge.  Exercize routines, stretches, yoga, meditation early morning, help keep ones mental and physical health. They are most important. They form the basis for the whole day and lay the foundation for getting things done. This is where the process sets the tone and helps get the best results. Once this is established one can let the ebbs and flow of work motivation and feeling ready to work happen, seeing them as natural, without concern that one won't get done what needs to be done to be effective.