The acquisition of Wachovia is now showing up in huge losses at Wells Fargo Bank. Fourth quarter losses for 2008 are $2.55 billion. With the Wachovia acquisition Wells Fargo took on $219 billion of commercial real estate and corporate loans and a large number of toxic pay-option mortgages. Wells Fargo has set aside $21.7 billion to cover losses as the slump in real estate markets continues.