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Constantly looking for knowledge and looking to learn is the important thing in delaying and cutting onset of dementia. Travel, going to museums, reading new books, exploring new fields, learning a language, staying socially active, trying out a new sport or activity, talking to people young and old, are all way to enrich one's life and this also reduces cognitive impairment. The idea of cognitive reserve means that ove a lifetime these activities taken up when we are of young age stay with us for a lifetime and cumulatively improve our cognitive faculties as we grow older compensating for any loss over time.

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New Harvard Medical School studies showing importance of lithium in the brain to prevent Alzheimer amyloid plaques and tau tangles, shown in this report of Washington Post by Mark Johnson. The studies at Harvrd Medical School will appear in Journal Nature. A 2017 study in Denmark showed presence of lithium in drinking water lowering dementia. The studies done on mice have to be now tested on humans. The brain uses only very small amounts of lithium to maintain the good functioning and prevent plaques and help neurons to communicate and talk with one another. Lithium helps form the myelin that coats and insulates the communication lines and helps microligial cells clear cellular debris.

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Research by Allen Roses, director of Duke University's Deane Drug Discovery Institute, and continuing research on the ApoEgene that has aclose link with Alzheimer's. In 1993, Dr Roses's research showed that people who have avariant of the ApoE gene have an unusually high risk of developing Alzheimer's. THese studies have been repicated by other scientists. In research presented at the international conference of Alzheimer's deisease in Vienna, Dr Roses and this team show that they have found a gene linked to ApoE called TOMM40. This gene had mutations that involved a small number of extra copies of aparticular building block of DNA in some individuals and alarge number of extra copies in others. Individuals with alarge number of extra copies- knownn as the "long repeat" version of TOMM40- coupled with ApoE3 develop ALzheimer's an average of seven years earlier- at about 70 compared to the individuals have the "short repeat" version.

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Tau proteins in the blood is a cause for Alzheimer's. Scientists in Sweden have found a way to detect this protein in blood tests using kits that are commercially available. This detection can be 15 years earlier before the onset of the disease. This is a revolutionary finding and would make it possible to screen for Alzheimer's early on.

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New medicines for Alzheimer's includes an old cold medicine from Russia called Dimebon it will jointly develop with a small biotech company named Medivation in San Francisco.

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Marty Makary, John Hopkins surgeon, is the DJT nomnee for head of the US Food and Drug Administration, FDA. Here a colleague of his at John Hopkins offers her experience working with Makary.  Leanna Wen says Makary is concerned about plastics, dyes, preservatives and chemicals that are entering our bodies and causing disease. Diseases that were not so prevalent one or two generations back are widespread today, says Makary. Makary wants to know why. Why has obesity quadrupled among young people in the US?Makary is also asking questions about why rates of childhood obesity are 5 times lower in Japan. Makary tell this Post reporter that ultra processed foods that are loaded with chemicals such as preservatives, artificial dyes and thickeners , take up 60% of calories Americans consume. This and poor food habits of today can cause diabetes, cancer, heart attacks and dementia. Pesticides and microplastics can cause early onset Alzheimer's and autoimmune diseases, attention-deficit/hyperactivity disorders. Makary wants medicine practiced in the US to direct resources to prevention, not simply hand out medicines with increasingly risky side effects. ...

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Nestle will create a new subsidiary called Nestle Health Science and a research organization Nestle Institute of Health Sciences, "to pioneer a new industry between health and pharma." Nestle sees disease prevention as a big part of healthcare in the future. The new company with an investment of 500 million euros over the next ten years will work to develop new nutritional products for diseases such as diabetes, obesity, cardiovascular and Alzheimer's. After sale of its stake in Alcon unit to Novartis for $28.3 billion, Nestle is almost debt free and can invest in developing new nutritional products without needing a return in the short term.

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This exceptional and detailed WPost report by Rosenwald, Boorstein and Clement on Pope Francis's popularity, also shows that on other aspects of the Catholic community's openness in the pews change is slow and gradual. In the parishes and on the pews for practicing Catholics there are not many signs of change. And Catholics who do not go to church are not coming back to the pews in increasing numbers. A slight surge under Pope John Paul II after his visit in 1993 for World Youth Day faded out, and this time the situation with Pope Francis's visit looks to be no different. About 1 in 8 Americans consider themselves former Catholics, according to the 2014 Pew Religious Landscape Survey. The Post-ABC poll of September 7-10, 2015 shows 45% of self-identified Catholics saying they attend Mass about once a week or more frequently, 19% attending monthly, and 35% saying they attend less frequently or never. There is a large gap between Pope Francis's popularity among Catholics with about 75% holding strongly favorable views, compared to 47% strongly favorable for the Catholic Church. Kathleen Cummings of the Cushwa Center for the Study of American Catholicism at the University of Notre Dame, says the difference is because Pope Francis has accentuated the positive. The Pope's own roots in Argentina and his practice of a more humble Catholicism as a bishop, his intermingling with people in the subways in Buenos Aires and in poorer neigborhoods of the city, not only affirms the original teachings of the Church, but also affirms this at a time when the bishops and the Church have drifted away from the original message, in a period of increasing social disparities in the Western World, Latin America and Asia. The Pope has called for helping immigrants, migrants, refugees, the poor, and the environment. Most people in the U.S. are comfortable with the Pope's activism on social issues and saying this before a joint session of Congress in the U.S. on September 25, 2015. To shake up the lethargy in the Church hierarchy Pope Francis described the bishops of the church in the Christmas 2014 message as "lords of the manor, superior to everyone and everything," and having "spiritual Alzheimer's." The extent of support for the Pope's activism shows how the public now views the need for someone of the Pope's stature to speak out on issues of social, economic and environmental change. Only 14% of Americans in the September 2015 Post/ABC poll say Pope Francis should be less active. 30% of Catholics say more active is better, and 50% say continue the way he is. And over half of non-Catholics want him to continue to speak out. Issues of the role of women in the church, abortion and same-sex marraige continue to create differences. By focussing on the original teachings of the church for humility, a humble church, and serving the poor and less fortunate, the Pope has reached the hearts of most Americans and people around the world, in a way unimaginable only a few years before....

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Krugman points out that in American history even presidents who did not read much and were not very qualified were able to perform well in office because of very qualified people in the cabinet positions. Reagan was not a avid reader yet he had Shultz at State and James Baker at Treasury. Mnuchin is not anywhere near being qualified as James Baker. Tillerson may be qualified as a CEO of a large energy company, but lacks the experience of Shultz. During the last years of his presidency Reagan may have felt the effects of early Alzheimers. Checks and balances also helped to make the system work under presidents so that they did not overreach their powers.  Krugman is skeptical of the way checks and balances would work under president Trump and sees some second rate appointments in the administration. He points to the departure of Mike Flynn and the controversies surrounding the Russian meddling as very different from the situations faced by other presidents with weak qualifications.     ...

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Lisa Ridzen a sociology student lives 550 miles north of Stockholm. She is the author of a story about older people, Bo an 89 year old born in 2015 who lives with his wife Frederika who has early Alzheimers and a dog in northern Sweden. It is a story about the difficult life of the elderly in today's society.

Ridzen says- "If I may indulge in a bit of politics, I think we're really heading in the wrong direction. If it were up to me, our elders would be fed with a golden spoon." She is aware of the conditions for the elderly- not so good today, as they struggle to live their lives neglected by a society run by private groups for profit.

The book has struck a nerve- in Sweden where it sold 200,000 copies. It is set to be translated into French in 2026 by a Quebec publishing house, and translated into 30 languages.