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Stuart Broad's remarkable achievement of 500 wickets as England beat West Indies in the Third Test at Old Trafford. He joins Glenn McGrath and James Anderson in an elite club of bowlers. He was made man of the match and of the 3 Test series after taking 10 wickets in the Third Test and hitting a quick 62 runs. 

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Questions raised about Dr Pazdur's decisions at FDA for anemia drugs made by Amgen and Johnson and Johnson. Dr Pazdur is head of the FDA office that regulates oncology drugs, all cancer drugs. Dr Pazdur's review process and decision shows how reviewers are human and their own experience helps determine what they see prominently. His experience with his father who suffered severely from the side effects of steroid drugs would make him aware of the the other effects of drugs. He is an oncologist, his wife is an oncology nurse, and some relatives have died of cancer, so he has lived with cancer patients. It appears from close associates that he like open communication and hears all sides but makes the final decision himself. He had an experience with a drug for lung cancer Iressa made by Astra -Zeneca, which the FDA approved based on testimonials, but not enough statistical evidence, which later failed and approval had to be withdrawn. This may have made him more inclined to look for strong results and statistical evidence before concluding on the safety and effectivenes of a drug. An approach evident with Amgen's anemia drug. It also appears that the FDA is not clear on whether the drug's effectiveness is to be judged by what result, is it whether it prolongs life only that counts, or whether the effectiveness in relieving significantly the symptoms of a patient even if life is not prolonged. There is the controversy surrounding the FDA's rejection of a drug by Genta Inc Genasense that relieved patient symptoms for leukemia but did not prolong their life. These and other questions continue to give sleepless nights to people at the FDA and outside as the drug review process faces difficult balancing act between what to give importance and what direction to take with a drug in patient's interests. In Dr Pazdur's case this is made more difficult as he thinks every day of his father who died in 1979 and suffered from the side effects of steroid drugs, went blind when Dr Pazdur was only a teen, and had pulmonary fibrosis and diabetes. He is described by doctors who trained under him as gentle but did meet a patient's eyes and tell him that he had to come to terms with his disease. ...

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US president Biden's $2 trillion Families and Workers plan, for early childhood education, paid leave, healthcare and climate change investment, is coming up for a vote in Congress. Paid leave that also includes maternity leave and leave that would help women return to the workforce, has been added back to the bill. Community college aid was earlier removed from the package with resistance from private colleges that expect to lose tuition paying students, even though male students are falling dangerously behind in attending college without government support. The Biden administration is facing resistance from just a couple of Democratic Congressmen- about five led by a Congressman from New Jersey, and 2 Senators from Arizona and West Virginia- on community college government aid that helps young American men and women from the working class and on paid leave that helps women. Many Republicans have supported taking this action for renewal of America on serious issues that face the country, making it likely that these issues will only become more pressing in the next three years. Sometimes as is happening today some isolated or eccentric situations can block major legislation for the good of the country such as the makeup of a Congressional seat in New Jersey with large pockets of conservative Republicans who oppose spending, and conservative instincts of two Democratic senators from Arizona and West Virginia. This WSJ report looks at Biden's position that deterrence when filing tax returns will generate close to $400 billion and not $150 billion that the Congressional Budget Office says is its estimate. To accomplish this Biden plans to spend $80 billon in large investments to increase the resources of America's tax collecting agency. Much of this was never done and policies geared to where large corporations never paid their fair share of taxes. The first step was to prevent outshoring of headquarters to reduce taxes- and this was achieved in the first year of the Biden Administration with over 100 countries agreeing on a corporate minimium tax. In the same way president Biden now seeks to correct other flaws in the tax system so that much needed investments can be made by generating new revenue not just in infrastructure, but for renewal of America through renewal of support for women, children, and America's working classes. Much of that was badly neglected by different  administrations over the last three decades.     ...

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Following the fifth North Korean nuclear test DW.com talks with Rudiger Frank about the test and what this means. Frank says the negotiations with North Korea and efforts to limit the program so far have been a colossal failure. Tests have continued and without a change in strategy more tests will be followed by the usual condemnations by world leaders and further sanctions. Frank says this change in strategy would include recognizing North Korea as a nuclear state, and getting North Korea to ensure the weapons are safe and secure in the country, getting a clear idea of what and where the weapons are. The International Atomic Agency would be asked to go in and make inspections. The next step would be to freeze the program at some level agreed to. This is a tough step to take but it only recognizes the reality of the situation, and continued development by North Korea of nuclear weapons if no steps for change are taken. 

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Experts say CEO's have constituencies in the form of employees, shareholders and customers. This has affected CEO's as they responded to president Trump's comments on the Charlottesville attack.  Even the cautious optimism that CEO's maintained during the early months of the Trump administration- as they sought not to miss out on representation on advisory councils- has now faded. Most CEO's have decided that it is not worth having this voice in advisory councils when they have to be seen as supporting positions on racism and culture they cannot support. One by one the actions by Trump on the travel ban, climate change agreement withdrawal, Charlottesville attack,  has led to a shrinking of support. From non-involvement in Trump's campaign but cautious optimism, to a sense that it is not possible to work with the president without violating deeply held beliefs. Gini Rometty of IBM told employees that dialogue was critical to progress, but that " this group can no longer serve the purpose for which it was formed."  A sense that not much would be accomplished, and the reputational cost for business was too high to make it worth the effort. In the span of 3 days three advisory councils to the president were disbanded. ...

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The 64 mile highway known as the Gardez-Khost Highway has cost $121 million upto this point. The final cost is expected to reach $176 million. At $2.8 million a mile the cost overruns on this projects are over 100%. Parts of the road run through Taliban territory and may never be completed. Security for the project has cost $43.5 million, according to USAID officials. This involves among other things payments to a local figure named Arafat. The road connects two provinces, Paktia and Khost, and runs through rugged mountain terrain at 9000 feet. At the original estimate of $69 million it was considered a good investment for linking these areas to Kabul.

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Does a 10% reduction in tariffs on China with the October 30 2025 agreement- made in Busan South Korea at APEC meetings- make a difference for companies relocating from China? It only does for smaller companies who are stuck with Chinese sources. Larger American companies prefer to diversify their supply chain and continue to relocate part of their factories to Vietnam, India and other countries knowing that the tariffs game will end up with allies EU, Japan and India in the 10-15% tariff range as a concession to US for putting up with trade disadvantages and job losses 2000-2025. China's will still be at 47% in comparison and the fentanyl issue causing serious questions to be asked by the American people which have not been grasped in China or even in the US by companies and politicians.   Does it affect the urgency and general shift out of China? The fentanyl issue is unlikely to change and it is likely to do lasting damage to China's credibility to a degree that it not clearly understood in China, and even not fully grasped even in the US today because of the sheer size of the number dead- more young Americans dead from fentanyl than in the Korean, Vietnam and First World Wars combined. Other issues are technology that has been transferred without a proper assessment of the importance to national security, the need to shift the manufacturing base back home that US industries have inadvertently and carelessly shifted to China in the disastrous Bush and Obama years 2000-2016, and for the jobs, the wages, and cost of living concerns when supply chains are outside one's control. This article asks the question about tariffs on India and Brazil as being contradictory and showing a lack of consistency in tariffs. India is compared to China with India facing a 50% tariff because of Russian oil purchases, and Brazil a 100% tariff related to treatment of former president Bolsonaro even though US has a trade surplus with Brazil. One expects that at some point India and the US will come to an agreement that lowers the tariffs in a way that was done with the European Union to bring it closer to 10%. China's tariff to be sure is still around 47% dropping from 57% a concession for rare earths and for the upcoming elections and economic concerns not because of policy intent which has not changed on  strong action for fentanyl which is also part of the Appeal to the People in the DJT base.   ...

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Office buildings are being turned into apartments in large American cities like this one at 55 Broad Street in New York City. Hybrid work has made the huge office space of daily commuters obsolete. Subways and transport is also used at a fraction of its capacity. The remote working trend is sending vacancies soaring in office markets in the US and in the big cities. Businesses using hybrid work are leasing less space and migrating to newer buildings with modern designs, good locations, outdoorsy feeling, and abundant amenities.

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It is not enough to think highly about work life balance of people around us, one has to free oneself from the constraints that make it hard to achieve that balance. As shown by studies in Finland about entrepreneurs, 40% of people in one study crossed the line from workaholic to work addict. Worse making the addict a role model is damaging to the younger generation. Tesla CEO Musk is not a role model for a young generation that values work life balance. It is also essential for healthy living.

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WSJ says GM straddles the past and the future. GM's plans to invest $11-13 billion each year for new electric vehicles. GM also plant to cut costs by $2 billion to maintain profit margins as car prices drop from higher levels. GM US largest automaker profit in 2022 kept up the pace of 2021 by remaining at over $14 billion. As car sales decline in 2023 GM plans to offer sales incentives and make up for this by cutting costs in corporate and other overhead.

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Bhupinder Bhalla, the Secretary, Ministry for Renewable Energy in India, talks to The Hindu's Jacob Koshy about India's plans for solar panel manufacturing. He says a key bottleneck is reliance on Chinese made components such as poly-silicone wafers. Manufacturing these components in India is key for the health of the solar ecosystem in India. Once this is established- and Bhalla goes over the action being taken- India will be able to export solar panels by 2026. He expects 40GW to be fully commissioned in the next 2 years.

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India is seen as critical for the US to develop alternatives to the existing supply chain where manufacturing is concentrated in only one country. US is positioning itself as a key supplier of defense needs of India through joint development and manufacturing in India. GE has a proposal to build jet engines in India, which Jake Sullivan, US National Security Advisor, calls just the kind of effort that will make it possible to rapidly build up the American relationship with India for advanced technologies and the supply chain in manufacturing. 

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This years pension hike of 5.35% in Germany is being completely eaten up by the inflation of 5.1% leaving pensioners in the same situation as before after many years when no adjustments were made. The catchup factor for meeting cost of living changes and inflation was put on hold by chancellor Merkel in 2018, another way social goals were not met under Merkel while infrastructure and child care were also neglected. Only now under a SPD Greens coalition are these problems of falling standard of living being tackled.

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Germany's Siemens and chancellor Scholz say the lack of a turbine from Siemens is not the reason why Russia is reducing supplies of Nordstream pipeline gas. The turbine is ready to be shipped to Russia if Russia wanted it. 

Mr. Scholz is looking at keeping 3 remaining nuclear plants operating which would meet 6% of Germany's needs. A review of nuclear plant operating condition is being done to make the decision to continue with nuclear energy and not phase it out completely.

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"For months I was asking for equipment," Martin Hirsch, head of the Paris hospital network tells president Macron, "and we had only enough for 3 days to fight against the coronavirus." The French president told one hospital " we undoubtedly made a mistake, we should have done it 10 years ago," as some increase in funding came only in January of 2020. France had a tenth of the intensive care beds in Germany and a far higher fatality rate says this report in France 24.

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The chairman of the Economic Advisory Council to the Indian prime minister, says India will grow at an accelerated pace after the worst effects of the pandemic are over by 2021. The changes introduced by the prime minister in the economy should make a big difference in growth. Compared to the growth with centralization in India Acts of 1919 and 1935 when there were concerns about holding avast country together, future growth will be based on decentralization, says Bibek Debroy, who is also a member of Niti Aayog.

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Shyam Sunder Jyani, professor of sociology in Rajasthan, India's driest state, fights desertification by personally funding the planting of 2.5 million tree saplings. He ha been doing this for the last 15 years. In June 2021 his project Familial Forestry won the Land for Life Award of the UN Convention to Fight Desertification. Jyani goes from village to village teaching people how to nurture trees to make the landscape hospitable. This is a land in Rajasthan state where summer temperatures can reach 45 degrees Celsius or 113 degrees Fahrenheit.

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The price of gas powered cars and EV's is closing, to about $5000 according to Cox Automotive. Tesla is cutting prices because of new competition from Japanese, Korean and German models in the US market. China's BYD is also in the global market with new battery technology that cuts cost. Batteries make up 40% of EV car cost. The cost of making EV's will drop to becoming the same as gas powered models by 2027 as companies get more experience in the new technologies, says Gartner.

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President Biden makes clear US commitment to Taiwan's defense. He said in Tokyo during his Asian visit in response to a question would the US intervene militarily if Taiwan was invaded. He said "Yes. That is the commitment we made." Biden said he supports the One China policy that there is one China, but for China to take Taiwan by force- "It would dislocate the entire region and be another action similar to what happened in Ukraine. So the burden, is even stronger."

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The opposition to wind and solar energy comes from environmental groups and local authorites. In Italy 90% of wind turbine projects are opposed by local authorites. Europe under plans made by Germany and other countries seeks to remove the dependence on Russian energy by massive investments in solar and wind energy. This makes overcoming opposition to free up the needed climate change action of major importance. This action also  removes dependence on Russian energy following the Russian invasion of Ukraine. 

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Customer rage is on the rise especially in the airline and hospitality industry in 2022. Dealing with it the right way is so important for airlines. Listening is very important. Saying I can't do anything about it, or asking people to just put  with whatever is happening is the wrong way to handle it and can only make things worse, say experts.  Airlines that show disrespect now may find that customers remember this for a long time and avoid such discomfort in the future.

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Nikki Haley lost the New Hampshire primary yet made strong inroads among Independent voters. The adjoining analysis in WSJ shows how Independent voters are an important factor for 2024, and could affect the outcome in a changed landscape. President Biden looks to restore the kind of voter support that propelled FDR and Harry Truman, John Kennedy right up to the 1960's. In that landscape the Clinton Obama years fade in significance as workers in manufacturing once again form the core base of the Democratic party.

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With a win in the Kingswood byelection, a Tory stronghold, Britain's Labor party is now seeing a real shift of voter sentiment for a large majority in parliament in the coming general election. Britain entered a recession in Feb 2024 and the Conservatives have no solutions for the economy after many years in power, and 4 prime ministers in a constant change of leadership. Britain also lacks the resources that make it possible to have the kind of investment and scale of investment in the US that president Biden has launched.

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Boris Johnson and Nicola Sturgeon leave the Tories and the Scottish Nationalist Party weaker than before providing Labour an advantage in England and Scotland after ten years of austerity and Scottish nationalist policies. Labour's loss of Scotland to the SNP made it hard for the party to win a parliamentary majority in elections. Boris Johnson appealed to Labour's base in the north of England without any significant policy accomplishments to back it up. All this is changing with Labour sweeping the local elections recently.

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November 18, 2020 WSJ ran the editorial from the Editorial Board- Rage against the Voting Machine. Rejecting the claims made by Mr. Trump and others about the 2020 election. WSJ cites this editorial and an Op-ed by the CEO of Dominion on its pages that showed its position was not affected by FNN even though News Corporation is the parent company of both. And showing its independent judgement after the election of president Biden with a margin of over 7 million more votes, in rejecting such erroneous claims.