LyrArc Article Gist
Americans Harvey Alter, Charles Rice and Briton Michael Houghton win the Nobel Prize in Physiology and Medicine for the discovery of hepatitis C virus, which causes liver cancer. Before this discovery and the test for bloodborne virus giving blood transfusions was very risky as it could transmit Hepatitis C virus. Blood banks then used the test to make sure donors did not carry the virus. We now have millions of people benefit from safe blood transfusions and safe blood products. Drug makers then developed medicines for treating Hepatitis C virus. Dr. Alter worked at the U.S. National Institutes of Health in the 1970's and identified the unknown infectious agent that was not Hepatitis A or B virus. Dr. Houghton worked in the 1980's with pharma firm Chiron and isolated the genetic sequence of the then unknown virus. He now works at the University of Alberta in Canada. Dr. Rice, a researcher at Washington University in St. Louis found a component at the end of the Hepatitis C virus genome that played an important part in its ability to replicate. ...

LyrArc Article Gist
Israel vaccination drive has now reached 2 million people for the first dose and 400,000 for the second dose. What do early results show? As the effectiveness is only 52% after the first dose, according to Pfizer for its vaccine, vaccination drive is only one part of the solution. The number of cases in Israel are high at 10,000 a day. There is concern about the ultra-Orthodox community following the protocols and rules for prevention. Ben Gurion International Airport may be restricted to only essential flights. A mutation variant of the coronavirus, a UK detected variant, is seen as making up about 30% of the cases and could make up the bulk of cases in the future. Lessons being learned are that Pfizer vaccine is effective at about 52% for the first dose. Only after the second dose are enough antibodies triggered to resist the virus effectively. This can be as much as 6 to 12 times the increase in antibodies for second dose, compared to what happens after the first dose says the Sheba Medical Centre at Tel Hashomer, Israel.   ...

LyrArc Article Gist
A 41 year old doctor, Vasant Narasimhan, is the new CEO of Novartis in Feb. 2018. Under Narasimhan R&D is expected to get prominence. His predecesor Mr. Jimenez's focus was on developing new prescription drugs. Dr. Narasimhan sees a shift to new technology, improving data science and digital capabilities to discover new medicines. This shift raises the possibility of a spinoff of the Alcon eyecare business and the Sandoz generics business.   Narasimhan joined Novartis in 2005 from consultancy Mckinsey & Co. and becoming head of R&D. He is expected to push a series of tech based initiatives including artificial intelligence to be used for new biomarkers showing effectiveness of treatment, new sensor technologies developed with Microsoft. This shift is a result of the earlier effort under previous CEO's to make up for the loss of patent protection on profitable drugs by diversifying into consumer healthcare. During the period under Jimenez Novartis share price performance was mediocre, rising 41% over 8 years. Its business is stagnant with a 1% increase in 2017 for revenues, the first increase in 3 years.   ...

LyrArc Article Gist
AP VoteCast shows over half of Americans and 8 in 10 Trump voters think support for transgender rights in government and society has gone too far. About 90 of Republicans, half of Democrats, and two thirds of Independents think support for transgender rights in government and society have gone too far. The situation about allowing transgender persons in women's locker rooms offends most women. Abortion rights is an issue for two thirds of women but half of the same women think transgender rights having gone too far, they cannot support transgender people in their daughter's locker rooms at school. Cultural issues such as these inflamed the situation with the signs in Madison Square Garden saying "transgender the hell out of locker rooms in our schools." What would FDR and Frances Perkins say about this, their whole lives spent trying to figure out a way for unemployment insurance and stabilizing employment. The net result is that only about 20-25% of women thought abortion was the issue, and 60-70% saw the economy as the main issue. ...

LyrArc Article Gist
The Guardian's Geof Lemon shows how India's lower order collapsed not able to hold on for 14 overs or just one hour on the final day of the MCG Test in Melbourne, Australia. After 30 from 103 balls Rishabh Pant became impatient without a goal in mind and took aim at the 104th from Travis Head over midwicket into Mitchell Marsh's hands. This started the collapse when the tea session was close at hand on the final day and India could easily have batted out the rest of the day. Boland, Cummins, and Lyon ran through the lower order with some excellent catching in the field. Australia lead 2-1 as the cricketers head to Sydney. The Indians have a lot to think about, including the absence of Shubman Gill, the failure of Rohit Sharma in batting, the Australian lower order Lyon and Cummins putting up resistance and the Indian lower order folding so quickly in the final hours on the fifth day. For the Australians a record is broken with 75,000 watching the final day of the Test cricket at MCG cricket ground. ...

LyrArc Article Gist
James West, energy analyst at Barclay's Capital, who co-authored a survey of 402 companies, estimates that the oil industry will spend $490 billion in 2011 to search for and extract oil and gas. This is up 11% from 2010. This spending includes increases in costs for finding and extracting oil and gas in hard to reach areas. The largest companies, including Exxon, Shell, Chevron and BP, are expected to increase spending by 16% to $108.6 billion. Chevron recently announced a 29% increase in spending, partly to develop large off-shore projects in Western Australia, the South China Sea and the Gulf of Mexico.

LyrArc Article Gist
A seven member panel formed by Toyota to look into Toyota's recall problems made its recommendations recently. The panel's report says Toyota was not good at responding to criticism from outside. Company executives looked at complaints about sudden acceleration defensively or skeptically, and viewed regulators in an "adversarial" manner. The NHTSA also has come under criticism in investigations, because to some extent Toyota's close connections with the NHTSA made it possible for the company to drags its feet in responding to complaints. Edmunds.com CEO, Jeremy Anwyl, says Toyota has a stable and predictable way of doing things and this does not work well in a crisis, leaving Toyota uniquely vulnerable to this. The insularity of executives in Japan because of the lack of non-Japanese on the Board. and in other important positions, magnifies the problems when they are rooted in a crosscultural environment. Such complaints in the U.S. media are viewed differently than in Japan. The report also pointed out that safety and quality are two different things - that processes that improve quality will not necessarily produce safe vehicles. By putting safety under quality and making everyone responsible for quality, no specific executives were assigned responsibility for safety. One of the lessons learned from the recall crisis is that specific responsibility needs to be assigned for safety, and the person in charge has to report directly to the President and top managers. One of the panel members, Brian O'Neil, a former president of the Insurance Institute for Highway Saferty, says the old adage is true in this case- when everyone is responsible, no one is responsible....

LyrArc Article Gist
Nationally the new Omicron offshoot variant, the XBB.1.5 represents 40.5% of the cases in the US by Dec. 31, according to the Centers for Disease Prevention and Control or CDC. In New England and New York it is about 75% of cases and is a rapidly rising variant in Europe also. Only 38% of persons over 65 years in the US have got the updated covid booster bivalent vaccine shot.

LyrArc Article Gist
Jean-Luc Melenchon is making a steady rise from third position in the polls for the French presidential election in 2022, says this report in FR24. Melenchon supports shifting from the presidential system that concentrates power in the office of the president to a system that gives more power to elected representatives. The presidential system was set up in France after indecisive coalition governments prevailed in the period before 1950. 

LyrArc Article Gist
About one third of winter wheat in the US is expected to be abandoned and unharvested because of drought conditions. This report in WSJ says it is the worst rate of abandonment of a wheat crop since 1917, including the dustbowl conditions of the 1930's. Kansas, Oklahoma and Texas are big producers of wheat. Climate change is being noticed in the drought conditions that are affecting American agriculture,

LyrArc Article Gist
A new plan of the Theresa May government in Britain commits the UK to be part of the EU customs union long after Britain leaves the EU. This avoids the setup of a visible border between EU and Northern Ireland. Ireland remains part of the E.U.  Having a permanent arrangement is needed so that the peace process in Ireland remains in place. A hard border is fraught with consequences of unsettling this.

LyrArc Article Gist
About 30 million Mexican children ages 4 to 18 years will be taking lessons on television. School has been suspended since March. With 60,000 deaths and the third highest fatality rate after Brazil and the U.S. Mexico's government has chosen to take this step. Television reaches 94% of the country compared to 80% for the internet. Radio lessons will also be broadcast. Here children are shown taking lessons on television.

LyrArc Article Gist
President Biden called for corporations to pay their fair share of taxes so that investments can be made in vital needs of the nation-US infrastructure, education and health, transport, public services. The NYT looks at companies where profits are shifted overseas to reduce taxes. In this case NYT looks into an investigation into shifting of profits to a Swiss subsidiary to avoid billions of dollars in income taxes. 

LyrArc Article Gist
Angolan investments are increasing in Portugal's economy. Privatization of Portuguese companies- required by the IMF as part of the bailout deal- is leading to investments by Angolan companies connected to the ruling party of Jose Eduardo dos Santos. Angola's Banco BIC is buying Portugal's Banco Portugues de Negocios (BPN) for $58 million, a fraction of the original asking price of $260 million. The IMF made the privatization of BPN a condition for Portugal to have the recent bailout loans. Angola's state oil company Sonangol has a 12% share in Portugal's largest listed bank Millenium BCP. There is a reverse migration of Portuguese to Angola. Portugal's foreign ministry says it showed 45,000 Portuguese citizens in Angola in 2007-2008. The figure in 2008-2009 had jumped to 92,000 as professionals lefto Portugal for Angola. Portuguese building companies are doing more work in Angola, and Portugal's banks are the basis of Luanda's financial system.

LyrArc Article Gist
India's chief of Defense Staff Chauhan talks to Admiral Paparo, Chief of US Indo-Pacific Command in Singapore Dialogue meeting in 2025.  He says China in northern borders no unusual activity had taken place. He also says after the loss of an aircraft, India was able to use different models of planes to tackle air bases in the opposite side in the Punjab region. At no time was there any thinking about nuclear options in this brief air war. “I think there’s a lot of space before that nuclear threshold is crossed, a lot of signalling before that, I think nothing like that happened. There’s a lot of space for conventional operations which has been created, and this will be the new norm.” “It’s my personal view that the most rational people are people in uniform when conflict takes place. During this operation, I found both sides displaying a lot of rationality in their thoughts as well as actions. So why should we assume that in the nuclear domain there will be irrationality on someone else’s part?” On China's involvement -“While this was unfolding from (April) 22nd onwards, we didn’t find any unusual activity in the operational or tactical depth of our northern borders, and things were generally all right.” ...

LyrArc Article Gist
It is important for a correct sense of the Middle East to see these British Arab states from Kuwait to UAE and Qatar in the context of British India if one is to see them as part of the modern world as India is. This is now US policy under DJT and has been under Biden for a peaceful economically advanced region. A third of Arabian peninsula Arab protectorates were run from British India from 1800 onwards. The Interpretation Act of 1889 listed the states under British India in the Arabian peninsula including Kuwait, Bahrain, Aden now Yemen, Oman, Dubai, Abu Dhabi, and they were listed along with Jaipur, Hyderabad and Bhawalpur. British Prime minister Clement Attlee wanted to give independence to these Arab states along with the independence of India and Pakistan in 1947. But this did not happen till 1971. In 1937 the first of many separations from the British Empire in India of Arab states was announced. Aden, now Yemen, was separated from the British Empire in India to the Colonial Empire. British Empire authorites in Delhi never wanted to administer these Arab states even though the British Indian Political Service ran each of these states till 1971. They were very poor and lacking basic infrastructure, things changed only after the discovery of oil in late 1930's. ...

LyrArc Article Gist
John Lyons of the WSJ writes in this report from Seoul, South Korea, that president Moon may have inadvertently contributed to the sense of the futility of talking to South Korea about missile defense when he opposed the installation of the Thaad, Terminal high altitude missile system, in his election campaign. This led to the U.S. and the South Korean government of president Ms. Park moving ahead with the system before Moon was elected. Moon is a human rights lawyer who favored improved relations with North Korea. Domestic South Korean politics were decided by younger voters alienated by the existing business structure, leading to the conviction of president Park and later the head of Samsung on corruption charges, and the election of Mr. Moon. In foreign affairs the picture is quite different as Moon is seen in South Korea as not being consulted by the U.S. as it frames policy for the region. South Koreans call this "Korea passing." As U.S. and Japan are directly affected by North Korean missile tests, the most recent on August 29th passing over Japan, U.S. president Trump consults with Japanese prime minister Shinzo Abe. People in Japan are cited in the NYT as saying recently, that they knew they had to worry about earthquakes, but had not expected to have to worry about missiles. A recent report in NYT showed that most people in Seoul have not prepared seriously to use underground shelters because they do not believe a war could take place with Seoul only 35 miles from the North Korea border. The U.S. policy is now focused on working with China, and coordinating its policy with Japan. A U.S. anti ballistic missile test was conducted from the ship USS John Paul Jones on August 29th. Moon has changed his position and now supports Thaad missile defense. South Koreans are apparently resigned to the prospect of "Korea passing." ...

LyrArc Article Gist
It is a major step to cut carbon missions in half by 2030. The Biden plan is to have majority of cars to be electric by 2032. It does not require a certain number of cars to be electric only requires carmakers to meet certain emission requirements overall and the carmakers then choose what the mix of gas, electric, hybrid would be. It also has concessions to workers unions and carmakers, and an understanding that there is resistance to buying electric when charging stations don't exist in adequate numbers and costs are high for electric. It does this by allowing accelerated development in 2030, 2031 2032 to do the job, as by 2030 enough capital investment and research will have happened to make this possible. This also seeks to not politicize climate change in the way the former president seeks to do as a realistic plan is needed and simply having no plan and eliminating the political opponent's plan and denying climate change is not possible in 2024 as in 2016, there is just too much happening in terms of floods and fires for people to not believe. Automakers and workers themselves believe that a plan is needed to fight climate change in 2024 even though these same automakers such as VW and large automakers in the US had a wait and see attitude in 2016. For the Biden administration listening to carbuyers, carmakers, auto workers and the general public to make the plan workable and meet real concerns is the best way forward in 2024. ...

LyrArc Article Gist
District court Judges are the first tier of the three tiered system of judiciary power. A series of US District Judge rulings stop the federal payments system, birthright citizenship, federal employees offered buyout plan, and other executive orders issued by DJT in first 72 hours in office. They were all designed to cut the federal bureuacracy in the US and gut agencies with overspending such as USAID $40 billion when rural America's needs are unmet, and tackle birthright citizenship which allows mothers to fly into the US and depart just to get citizenship for children. The White House plans to appeal these rulings to the next level the appellate courts in the US, all the way to the US Supreme Court. Some of the arguments against USAID $40 billion budget was that it funded bureaucrats pet projects, something that Senators such as Senator Rand Paul of Kentucky have fought against for 25 years. Coming after trillions of dollars in spending under the infrastructure Investment Act oversight over such spending is in the American tradition. No less than Harry Truman as Senator from Missouri made his mark by tracking down overspending and waste, during the Second World War. Another problem not discussed enough is that in today's world more can be done with good governance and leadership, avoiding unneeded wars, and investment from India, China, EU and US than can be done with $40 billion spread thinly over the whole world. Sri Lanka is just one example where its undoing is waging ethnic war, corruption, and India is leading its recovery in ways that USAID could never do. ...

LyrArc Article Gist
James Hagerty of the WSJ tells the story of John Boyer from Minnesota who as a software engineer developed the Liblouis, the first open source software, that is used around the world, to translate text into braille. Boyer said about jobs and dignity that to be respected in society one had to have a job, he knew what it was like to be labeled unemployable, and he wanted to see other handicapped people gainfully employed.

LyrArc Article Gist
The Raisina Security Dialogue, India's version of the Munich Security Conferen ce was attended by the security chiefs of 26 countries. It was held in New Delhi March 1-2. Security chiefs from UK, France, Japan were present. The Conference is organized by the Research and Analysis Wing, India's external intelligence agency and the National Security Council Secretariat  (MSCS) which reports to Mr. Ajit Doval, Indian National Security Advisor.

LyrArc Article Gist
Citing passenger safety as an issue Transport of London (TfL) says it will not renew the license of Uber in London. Other ride apps make efforts to compete yet may face similar issues. TfL says Uber was not sufficiently "fit and proper" to have the permit renewed again. Uber lost its operating license in September 2017 and then operated on a probationary license after safety issues were raised about unauthorized drivers. 

LyrArc Article Gist
OECD forecasts show global GDP increasing by 4.2% in 2021 and 3.7% in 2022.

Countries with rapid testing facilities and large scale vaccination efforts are likely to recover faster. Smaller businesses are more likely to fail and go out of business. The will be damage to socio-economic fabric in many countries. OECD calls for investments in education, health, physical and digital infrastructure, and cooperation across borders for vaccine efforts and public health.