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This excellent article by Peta Bee looks at how we can do anti-ageing efforts to keep our immune systems strong as we become older. She looks at work by an expert in immune cell biology, Janet Lord, who is head of the Institute for Inflammation and Ageing at Birmingham University. It is now proven that the link between ageing and immune systems can be guided in constructive ways. At sixty and seventy years age one can have the immune system of a 30 year old by doing a couple of simple things which are covered here from taking 10,000 steps a day, high intensity interval training on some days each month, occasional fasting on some days, high fibre diet and vitamin D. Walking, running or other forms of exercize affect a particular form of immune function called neutrophil movement in positive ways. Neutrophil movement because these cells are the main defense against the forms of bacteria that cause pneumonia. Neutrophils in older adults behaved in ways similar to that found in 30 year olds when doing 10,000 steps a day of exercize. Dr. Lord and other researchers have found. Dr. Jenna Macciochi, a lecturer in immunology at the University of Sussex, says about 70% of our immune system resides in our gut, making gut health very important for our immunity. Macciochi is the author of Immunity: The Science of Staying Well. Important for gut or gastrointestinal health is the eating of food that has prebiotic and probiotic effect. This helps reverse the decline of immunity coming with ageing.When we chew down on fibre in vegetables, fruit, beans or lentils we have beneficial byproducts called postbiotics that act as an interface between diet and immunity, that change the personalities of cells and circulate in our blood for regulation of immune system, says Dr. Macciochi. Postbiotics from eating dietary fibre tune up specific virus fighting cells that help us fight infections from flu and viruses, studies show says this report in The Times. Women in the UK get only 17g per day, men 20 mg per day of fibre. We need 30 mg per day of fibre and to do this we need to increase our intake of vegetables, fruits, whole grains, nuts, seeds and pulses. Also important is avoiding the inflammation that comes with ageing called inflammageing, says Dr. Macciochi. To do this do resistance training, weights, or using body weight such as lunges, push ups, squats. When our muscles move we produce hormones called myokines that help our immune cells function and keep inflammation down. She believes strength work is an absolute essential to rejuvenate our immune age. ...

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A You.Gov poll taken for The Times in the last 5 days says 9 out of 10 Tory voters have decided who they will vote for as ballot papers went out this week. And 60% will vote for Liz Truss who has widened her lead to 34 points over Rishi Sunak. Tory party voters for the leadership by a majority or 53% say Boris Johnson should not have resigned. Only 41% say Boris Johnson should resign. Mr. Johnson supported Liz Truss, as do most of the cabinet.

When asked who can get Tories a majority in the next election Truss at 39% has a 20 percentage point lead over Sunak. From this it appears that if Tories themselves and not the cabinet had decided Boris Johnson would still be prime minister, and Liz Truss takes on the premiers role with the same style and spirit of Brexit that Johnson brought to the role and would consider Mr. Johnson as part of the close advisers.

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Jagdeep Dhankar is elected vice president of India with 528 votes out of 725 votes from members of parliament. He is seen as an outstanding chair of the Rajya Sabha, India's Upper house of parliament, by Modi, Jaishankar, Goyal and others. He was an Advocate for the Supreme Court of India. He coms from a farming family in Rajasthan from the Jat community. He was a member of parliament and a member of the legislative assembly of Rajasthan. Dhankar was a minister of state for parliamentary affairs under prime minister Chandrasekhar. With his wide experience he goes back to the early days of the Janata Dal, the party that preceded the current BJP party. The president and vice presidential positions have now been filled with the best representatives of the tribal communities in India that make up about 110 million people in India, and a representative of farmers from the Jat farming community in the states of Rajasthan, western UP and Haryana.   ...

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Safety checks at Norfolk Southern are the subject of this report in the WSJ. The derailment of a freight train leading to spill of toxic chemicals in Ohio on Feb 3, 2023, led to concern about the safety practices at American railroads in the efforts to cut costs. The National Transportation Safety Board has opened a probe into the safety culture and practices of Norfolk Southern. One practice called PSR or precison scheduled railroading has been used by railroads in America to cut costs. This means fewer employees, longer freight trains as long as 3 miles, and fewer locomotives. The result is that employees count went down from 159,000 in 2011 to 115,000 in 2021 a drop of 28% even when freight dropped by 11%. This increased profits resulting in higher dividends and stock buybacks, with a heavier workload and less time off  even for sick days until a threatened strike. President Biden intervened to set a new pay and work deal and an element of fairness for workers. ...

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This Times leading article on UK government's coronavirus policy says it is inconsistent, and a muddled effort just as the third wave is accelerating. It asks the public to be cautious when going outside and still opens nightclubs with covid passports not required till the end of September. By August cases could reach 100,000 say experts so that the nightclub and bars reopening can only fuel the rise in cases. The British government must be aware that the Netherlands opened nightclubs and bars in June and this led to a sudden jump in cases with 40% of new cases coming from nightclubs.  The policy is undermining public confidence. It is doing this at the same time as it is asking people to self isolate for 10 days. The policy also does not require covid vaccination pass for all events and for shops and restaurants as is being done in France and in other countries on a regional basis as in Germany. 

 

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Coach Jitendra Singh who coached Hardik Pandya from his childhood days talks about the way Pandya has matured over the years since the Karan Johar chat show episode. Coach Jitendra Singh says Pandya told him- "Coach you won't hear any negative things about me after this." The death of his father who took his two boys to Baroda to prepare at a cricketing academy has affected Pandya.

In the recent IPL final Pandya showed his captaincy skills and his skills as an all rounder with 3 wickets for 17 runs including that of Butler of the Rajasthan Royals and 34 runs batting at a critical stage for a over 50 run partnership with Shubman Gill. Pandya is seen as very close to players and encouraging David Miller who took the Gujarat Titans to win the game with superb batting.

Here the Indian Express calls this a Kapil Dev moment for India as Kapil Dev is the only cricketer in Test history to have scored 5000 runs and taken 400 wickets.

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Jaishankar  of India and Blinken of the US join to say the world should not be divided into political blocs and that there is room for working together in different groupings such as the Quad, in the Indo-Pacific economic cooperation, as two largest democracies, and for the rule of law, open navigation in the Indian Ocean and Indo-Pacific. Both agree that polical complexity should not be reduced into black and white and simplified. For India Jaishankar says it means we are in a certain location in the world, there is history, our experience is different, all this shapes how we see the world. India gives voice to the aspirations of over 2 billion people in India, Indonesia, Bangladesh and other countries. It created the G20 out of the G7 nations.

Baerbock of Germany adds that Europe has to accept that in the past it when it backed colonialism based on attitudes at the time, when it supported Apartheid in Africa, it had made mistakes.

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Pope Francis recalls his days as a boy playing soccer on the streets outside his home in Buenos Aires, Argentina, with a rag ball because they did not always have a leather ball. "There was not always someone with a leather ball so we played with a ball made of rags, a pelota de trapo." Pope Francis was born Jorge Mario Bergoglio to Italian immigrants in Argentina. He calls it a great school of life for him being the goalie and having to take all the shots taken at him. His leadership has shown concern for the marginalized and the poor through the repeated economic crises and the current pandemic. In his talks with world leaders including Trump, Biden, and recently Modi of India he has shown the importance of taking good care of the environment, the downtrodden and the marginalized in society. 

Some of the influences in his life come from his father, an accountant from Asti in northwest Italy, who loved reading to the children and had a library.

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Car buying has changed permanently in 5 ways, says this report in WSJ. There are fewer cars made and fewer cars on manufacturer's and dealer's lots, cars are more expensive these days. Car sales have dropped from 17 million before the pandemic to 13 million and up only to 15 million in 2023 as more cars were made. Carmakers have learned to make money by selling fewer cars concentrating on the pricier cars and reducing cars available in the lower end of price range. Used car prices are up on average to $30,000. New car prices have surged to an average of $47,000 in 2022 and 46,000 in 2023.  New car loans are up from average $562 to $733. The share of leased light vehicles has dropped from 30% to 20% of cars sold and carmakers are offering fewer lease deals as demand is easily fulfilled. With fewer leased cars coming in the dealers have to actually go out and buy them. 

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This analysis by Gerald Seib in the WSJ shows the FBI chief Comey reopening the investigation into Clinton's email server just one week before election date November 8, as a move that does not enhance the democratic process because either way it will lead to questions why this was done at this late stage. The emails were found on a laptop used by Huma Abedin, an assistant to Hillary Clinton. Experts say the emails can be processed in a few days, and the FBI, the Justice Department are moving quickly to do this. 

Election experts say most of the decided voters for both parties will not be affected by this especially since most people will have made up their minds by now. Some voters who had questions about Trump might be moved to vote for him, and some undecided voters may be less enthused to come out to vote, though it is not clear at this stage. By mid week a clearer picture is likely to emerge. 

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France and Italy are imposing strict rules for their lockdown and tougher enforcement to control spread of coronavirus. India has imposed a quarantine, a total ban on leaving the home with a televised address by prime minister Modi that set a 21 day lockdown period. Modi said "if the pandemic cannot be managed in 21 days it would set India back by 21 years." 

Fines of $3000 euros are imposed in Italy and cars seized by the police. A special form has to filled out in Italy showing where one is going and checked by police if leaving the home. In France one needs an Affidavit of Movement by Special Dispensation is a filled form required for everyone outside the home. All open air markets are closed in France and drones are used to warn people outside.

All domestic and international flights in India are stopped. All domestic passenger trains and bus services in India are also stopped.

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Coronavirus testing is being ramped up in the U.S. as the Food and Drug Administration new regulations allow commercial labs to manufacture and distribute  coronavirus tests. Now many players can now acquire and conduct tests including state and local governments, hospitals, universities, and private companies. so that tracking nationwide distribution is still difficult. Deborah Brx the response coordinator of the White House task force on coronavirus says U.S. has completed 220,000 tests in last 8 days.  In New York the scaled up efforts in a region with over half the coronavirus cases in the U.S., 13,000 were tested on Monday, March 23. Some hospitals in New York such as Mount Sinai expect to do double or triple the tests a day in a scaling up effort by March 30. In Los Angeles a city councilman negotiated with a South Korean company for delivery of 100,000 tests a week, having already secured 20,000 new tests. Additionally swabs and protective equipment are also needed to conduct tests and labs need to process results with speed. ...

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Maggie Haberman has covered Donald Trump from the period before he ran for president in 2016. Here she looks back at this period and reflects on the trial in New York with Judge Merchan, the campaign trail, and reflects on what it all means today to the people of the 51 states. She says it shows a former president who sees his best days in the 1980's when the Trump Tower was built, the connections with the New York elites who at once ignored and embraced this new view of the world and a place for greed in this world. It is also a period that began with Reagan Bush and the start of the Iran Iraq wars, the Bush war in Afghanistan, the Clinton embrace of economics that led to decline in US manufacturing, the 2009 financial crisis and Obama's continued war in Afghanistan- a period of decline in standard of living of the American people and failure to invest in essential infrastructure to improve quality of living.

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Matt Garman, head of AI and Cloud Services at Amazon talks to Emma Tucker of the WSJ. Garman says Amazon was not slow, just being deliberate and thinking it through rather than coming up with something quickly as Microsoft had done with ChatGPT. He sees the need for regulation, only that it not create a situation where others including China go ahead and the US falls behind. This means that the US needs to coordinate AI rules with other countries including China, India, Russia, for comprehensive solutions on how AI is to be managed to work towards good.

On a five day week vs remote work Garman says Amazon takes the view that the creative work can best be done with humans interacting at the office. It sees this as essential for good work. On the 3 day week with 2 for remote work, the only problem he says is that everyone picks different 3 days and this leads to loss of human interaction at work.

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It is Tuesday afternoon in Volant, Pennsylvania, population 126 residents and a Minnesotan Walz is talking to farmers in rural parts of the state, farmers trudging their way to see him. In this part of midwestern America there is anxiety about the cost of living, about immigration, and about a way forward. It is here in Beaver County that Biden campaigned in 2008 and in 2020, and Walz is back in 2024 in the closing days to get his message across that America can be tough on immigration, and also invest in renewal by investing in the future, and controlling the cost of living, fighting monopolies and corporations that don't pay their fair share of taxes that can fund America's  rural infrastructure that has been neglected for three decades by both parties till the Biden legislation funding rural infrastructure renewal. This means getting the message out and fighting every step of the way in rural America that needs and deserves respect, says Katie Glueck.

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California Governor Jerry Brown reflects on what the Democrats missed in the last 4 years- the crisis of affordability of housing, for groceries. And with the border issues the unease about flow of fentanyl across the border that with transgender and culture that adds to unease is the silent issue Democrats failed to face up to for working class Americans. Orange County going for Democrats,  Imperial County going the opposite way, that says a lot about things today.  "When you see Imperial County going for Trump and Orange County going for Harris,” Jerry Brown reflected says this Politico report, a party that was winning wealthier, coastal Californians, but that had “lost a percentage of the working families.” "Democrats need to get their act together, focusing on the basic stuff — the economy, the environment.” ...

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Iran's efforts to continue its nuclear fuel enrichment programs and develop a nuclear weapon are running up against the European Union, the US and the interests of the world in nuclear non proliferation. After 5 days of war Iran continues to move in that direction.

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The Samaras government cuts some government perks including one that gave public sector civil servants 6 days of computer leave for spending more than 5 hours a day in front of a computer.

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The third or booster dose of vaccine is needed to take out the Omicron variant. The UK Health Security Agency analyzed data from 581 Omicron cases and thousands of Delta cases to calculate how effective vaccines such as Pfizer and Astra Zeneca were against the Omicron variant. This early analysis shows a third booster dose prevents around 75% of people from getting any coronavirus symptoms. The double dose of the vaccine however provides good protection against severe coronavirus that needed hospital treatment says the UK Health Security Agency. Of equal concern is the rate of spread of the Omicron variant. Here this BBC report shows graphs of UK National Health Security Agency which show the rate of spread is rapid with cases doubling every 2-3 days. For the UK which on December 10 had about 1265 cases this means says this BBC report that the number of Omicron cases could be well above 100,000 in the UK by the end of December. The BBC graph shows the curve for Omicron cases moving in a close to vertical direction upwards. Reports say the experience in South Africa where the Omicron variant was first detected is similar in pattern causing rapid spread. ...

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GM's operating income in European operations since January 2010 is a negative $2.34 billion. The continuing loss in European operations comes at a time when GM's performance is weakening in the U.S. GM is facing more competition from Japanese makers as they recover from the effects of the earthquake and tsunami of March 2011. GM had 82 selling days of Chevy Cruzes and 109 selling days of Malibus in dealer inventory in Jan 2012. Analysts estimate lower earnings of 42 cents per share for the last quarter of 2011. GM is freezing the salaries of 26,000 salaried employees and addressing a shortfall in its pension fund by switching to 401(K) contributions to reduce the risk.

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This Editorial Board opinion in WSJ says it supports the US Supreme Court decision upholding the law passed by US Congress on banning foreign adversary control of TikTok. DJT issued an Executive Order giving the president 75 days to study the situation about a sale of TikTok. Republicans in the US Senate say the president is required to follow the law set by Congress.

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It is hard these days to walk on streets in Germany, Austria and other European countries without the fear of being hit by a speeding bicycle. Some cyclists are known for aggressive cycling on city streets and make it difficult to go out for a walk without constantly being on the alert for bicycles. This is completely different from when bicycles were rare ocurrence.

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Chancellor Merkel's now widely quoted words were made in Munich on May 27, 2017, after a NATO summit meeting in Brussels and a Group of 7 meeting in Italy, in which she was disconcerted by U.S. president Trump's positions on NATO, Russia, climate change, and trade. These words "the times in which we could rely fully on others - they are somewhat over." Merkel added "This is what I experienced in the last few days." After the election of Emmanuel Macron in France, Merkel expressed great relief at the outcome of the French election with Macron winning about two thirds of the vote, setting the stage for the election in Germany after several months of difficult watching and waiting. Now there is new confidence in Germany shaping its own future, with France and the rest of the European Union without Britain. Merkel says she "experienced this" meaning that she had undergone a transformation in these few months, and visibly in the last few days. She was also sending a message to Germans and people of the European Union - "we have to know that we must fight for our future on our own, for our destiny as Europeans." This also complements tactically to form the approach of Germany and France at the leadership of the EU, as French president Macron said at the end of the Group of 7 conference that multilateralism was intact, and the U.S. and EU shared many common goals.   ...

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To the other reasons, callousness on social issues and towards women and immigrants, Rove adds additional ones. The lower voter turnout with ony 51.3% of voters turning out to vote in the 2012 U.S. presidential election, the poor timing of the convention when it should have been held in June, the lack of response to an ad blitz with negativity throughout the late summer that Romney lacked funds to respond to. He points to the role of the Super PAC's and the American Crossroads organization he created in preventing the Republican candidate from being strangled by a single ad blitz in the summer that spent 20% of election campaign funds of the Obama campaign.

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Experts say CEO's have constituencies in the form of employees, shareholders and customers. This has affected CEO's as they responded to president Trump's comments on the Charlottesville attack.  Even the cautious optimism that CEO's maintained during the early months of the Trump administration- as they sought not to miss out on representation on advisory councils- has now faded. Most CEO's have decided that it is not worth having this voice in advisory councils when they have to be seen as supporting positions on racism and culture they cannot support. One by one the actions by Trump on the travel ban, climate change agreement withdrawal, Charlottesville attack,  has led to a shrinking of support. From non-involvement in Trump's campaign but cautious optimism, to a sense that it is not possible to work with the president without violating deeply held beliefs. Gini Rometty of IBM told employees that dialogue was critical to progress, but that " this group can no longer serve the purpose for which it was formed."  A sense that not much would be accomplished, and the reputational cost for business was too high to make it worth the effort. In the span of 3 days three advisory councils to the president were disbanded. ...