LyrArc Article Gist
The Kristian Anderson memo to Dr. Fauci is the No. 1 story in the WSJ on June 5. This memo written on Jan 31, 2020 shows the initial reaction of the leader of five virologists to the coronavirus genome. Nicholas Wade writing in WSJ cites this memo as having missed the censors marker as the emails to Fauci were released under the Freedom of Information Act. The initial reaction is cited in the Anderson memo to Dr Fauci as seeing "unusual features" in the virus. These were in a small percentage of the genome, "so that one has to look really closely at all the sequences to see that some of the features (potentially) look engineered." Mr. Anderson goes on to note that he and his team of virologists 'all find the genome inconsistent with expectations from evolutionary theory." What does Anderson mean by this important phrase? Anything inconsistent with evolutionary origin has to be man-made is the conclusion drawn by many virologists including David Baltimore, cited here in the WSJ. Virologist later modified their stand saying it was evolutionary because of professional interest in not starting a what WSJ calls "storm of condemnation" over gain of function research, a exotic name for genetically enhancing the pathogenic power of viruses or increasing its transmissibility effect. Nicholas Wade is a Science writer who has worked for Nature, Science and The New York Times. ...

LyrArc Article Gist
A transformation of the scale of what De Gaulle did for France in about that same period 1954-1963, in 13 years transforming a agricultural state with 80% illiteracy under British rule in 1947- this happened in the former Madras Presidency, Madras state in post independent India. Schools and high schools spread across the state, national to the state public sector projects were brought for industry, and dams built for electricity to the towns and rural areas. That is the story of Madras in that period. It was all done with clean governance with Gandhiji's principles. The period after the 1970's led to governments with caste based politics with lower castes from a Self-Respect movement pitted against Brahmins and upper castes sort of like the Irish as a deprived caste pushing out the Boston Brahmins yet binging with it Tammany Hall style politics of New York in the turn of the century America. By the 1900's you had Theodore Roosevelt challenging this kind of Tammany Hall politics, for clean governance. In 2024 Modi is sort of like Theodore Roosevelt challenging the existing system in the Tamilnadu Madras state on the basis of seeking the Nation's development and modernization comparable to China and Japan by 2047 what is called Vikshit Bharat. This is the only way to understand it for Americans as Indian themselves don't fully understand many castes interwoven in India as different groups and nationalities are in Europe plus more stratification. ...

LyrArc Article Gist
The president telling Kamala "go for it kid. I love you.," and Kamala saying "I love you." The president saying that he is all in this campaign. The staff in Wilmington, Delaware grasped the emotion of the moment, and what it means for America. It may not be fully understood but it serves well the moment and this time in American history- there are now two candidates for president, Biden as the honorary unofficial presidential nominee, Kama as officially presidential nominee, and the to be selected nominee for vice president, not two but three in that team for the first time in American history- all inseparable to take head on the dangers to America's democratic institutions that George Washington by paying so little attention to himself, that Jefferson and Adams, TR, Wilson and FDR fought to protect through 2 World Wars, dangers from social media and television degenerated divisiveness. Katie Rogers tells the story of how on one summer afternoon in July, on July 22, 2024, the Biden campaign was converted into the Harris campaign all the way down to the memes popularity for Kamala. The president's call "to embrace her," the Biden staff with little time to express their emotions, all staffers in Wilmington become Harris staffers knowing also the deep loyalty that Kamala Harris had shown throughout the long weeks for Biden, and her strong feelings for being on the president's team. ...

LyrArc Article Gist
 Her mother was a real pioneer and large influence on Kamala Harris. Michael Kruse tells this story of Kamala Harris and the influence of her mother Shyamala Gopalan, a biomedical researcher at Berkeley, Cal and other national laboratories.  Shyamala had the same sense of adventure of America's pioneers on the frontier since George Washington in the  Pennsylvania country around Pittsburgh. And her striking attitude raising Kamala, one of two daughters, living in a minority neighborhood in the Berkeley area, and moving twice including to Montreal's McGill University and to Cal as a researcher. “Don’t let anybody tell you who you are. You tell them who you are.”  “Focus on what’s right in front of you, and the next thing, whatever that’s meant to be, will come."  "And … “don’t do anything half-assed.” Shyamala landed in Honolulu in 1958 when only 200 Indians were admitted each year, 1953 in all for the decade of the 1950's. America was 90 percent white and Berkeley was 98 percent white. America that we see today did not exist. John F. Kennedy and Lyndon Johnson opening America to immigrants from Asia happened years later in 1965 with the Immigration Act. She started classes at Berkeley in Nutrition on a $1600 scholarship.   ...

LyrArc Article Gist
New offices, making them less awful, (NO-LA) this is the trend says this report in WSJ. Reopened offices are opening on a voluntary basis. How will they attract employees back?  Try sweeping views, new yoga and wellness areas, "tech-free reflection zones,"  more conference rooms. This report looks at spaces by Accenture and other companies. Accenture adds sweeping views of the Hudson river, access to an outdoor terrace. The idea is to act as a pull, rather than a push. Unilever is changing offices into destination spaces where employees will come and work in 40% of the time. Salesforce is moving out desks to add more couches, TV's and whiteboards for teams. More offices are building spaces for 60% collaboration, up from 40% previously. Sanofi in Paris is adding options for breakfast, early dinner.  Other ideas are engagement days if workers are coming in only a few days a month. At Hightower this means one set day in the office a week, two engagement days a month for collaborative work. And workers are allowed to not coming one month a year and work from anywhere they choose.  ...

LyrArc Article Gist
Curiosity had a lot to do with the Renaissance in Europe, the Voyages of Discovery from 1500 to 1800, with the Discoveries in Science in Europe since the 16th century, and the Industrial Revolution in Europe.  Curiosity sets out a new way of thinking. This helped Europe to surpass Asia after the Renaissance. The Voyages of Discovery were motivated by an effort to fill gaps in knowledge about the world beyond one's shores in the Atlantic, and other oceans. Jamie Jirout of the University of Virginia shows how this works- The qualities needed are Interest, Creativity, Open Mindedness, Intellectual Humility, Intellectual Courage, Critical Thinking. This leads to internal curiosity and mental frame to be Intrinsically motivated to seek information, Identify knowledge gaps to think in new or different ways, be Open to things Unknown, Comfortable with risks of failure or mistakes, Challenge and change one's own thinking. This manifests itself in Behaviours that Explore and seek new information, Try things in new ways, Observation, Asking Questions and persisting after failure, questioning things verbally.         ...

LyrArc Article Gist
High speed rail networks from London to Leeds through Birmingham and Manchester get Tory and Labor support as the mood shifts to favor fast rail connections in Britain.

LyrArc Article Gist
In this audio BBC Witness History talks with Shuji Nakamura, the inventor of the LED lightbulb in 1992.  Nakamura shows the resilience and stubborn persistence against the odds that has given the world an extraordinary invention. The LED bulb does great things for climate change action because for example Califonria uses 35% of its electricity for lighting. The LED bulb cuts this in half and this means many coal fired power plants are not needed. In India, Indonesia and China this means lighting for about 3 billion people, with lighting for children studying in remote parts of India and China, and in Africa and Latin America. Nakamura took an unconventional route. He did his PhD in Japan not by going to school which is allowed in Japan, but by writing a paper on White LED development. He made a single minded focus on this goal. Nakamura says it made him angry that no one wanted to try new ideas and he persisted for years of research. At the time GaN research was done by less than one percent of researchers. Nakamura decided to try the path less trodden and by 1992 developed a blue light emitting LED bulb. Add phospor particles and blue becomes bright white LED. ...

LyrArc Article Gist
Ruffenach gives an excellent account of how many people describe their expectations and how it actually turned out in retirement, the good and the bad. He cites numerous examples to give as broad based a picture as possible. Health and active life, passions and interests, loss of self esteem in work for some and finding substitute interests, taking risks to try something new and the rewards. More people describe positive experiences in those surveyed. Health is the main concern for 41% in actual retirement, children and other things are all less than 10%. Travel should be planned early as it becomes harder as the years go by and one gets older. It is not as difficult as people think to make new friends in retirement, and this active social life with new friends can play a positive part in spending time. In addition there is the opportunity in retirement to take things slowly and leisurely, and spend time more on oneself and one's own interests.

LyrArc Article Gist
This report in the Times looks at president Macron in a holiday setting at the presidential place Bregancon near the military port of Toulon in the south of France. Macron worked hard on the European Recovery Fund and getting a $390 billion non repayable aid fund for southern Europe with chancellor Merkel of Germany through tough long negotiations with the Dutch and the Danes. His work with two provincial mayors as prime ministers, the last current prime minister Castex, in fighting the coronavirus is giving him much needed boost in popularity. Throughout his willingness to learn and to try new approaches without worrying about the risks, and his frank manner with perseverance has helped Macron as he navigated unknown waters. After a drop in the polls to about 30% he is now up to 50%, 18 months before the presidential election. This is good for France as strong leadership is needed after the pandemic both for France, French speaking regions, and in solidarity with former French Africa. ...

LyrArc Article Gist
AMD's ambidextrous strategy of incorporating circuitry developed by other companies in its chips. Modular chips would take chip circuitry developed potentially by ARM and other companies, and AMD is moving in this direction, says Rory Read, AMD's CEO. The chip industry is moving from separate chips towards chips for multifunction products called SoCs or systems on a chip. One advantage of SoCs is that they create savings in space and power especially for mobile devices. Both Intel and AMD are doing this for laptops and notebooks.

LyrArc Article Gist
This report in The Economist shows how Nairobi is coping with years of haphazard and disorganized development. As land prices jumped new investment has led to a unregulated disorganized building boom that has affected rivers and sanitation. The city's water supply and colonial era sewers are barely coping, says the Economist. To try to fix this the city has launched a demolition campaign for 4000 buildings. Meanwhile Nairobi's population has grown by 1.5 million over the 2009 figure of 3.1 million. Projects to build 200,000 low income housing is also underway. Four problems need to be tackled- a skills shortage, insufficent government investment, enforcement and rule of law, and last rent seeking typical of underdeveloped countries with corruption, complicating the tasks ahead. The biggest problem is large population growth for most African cities.

LyrArc Article Gist
The story of Lee Kun-hee who over 3 decades transformed an obscure electronics parts maker into the company Samsung is today, as a leader in smartphones and electronics. He was born in 1942, during the Japanese occupation of Korea and lived through the war years. He studied at Waseda University in Japan and George Washington University in the U.S. By the time he took on the position of CEO in 1987 from his father Samsung had grown from roots as a small fish and produce trading firm. It had then added after the war with Japan and the Korean War in the 1950's other lines of business such as sugar refining, textiles and diversified later into simple electronics such as radios and microwaves.  He was for change and once said to Samsung employees "change everything, except your wife and children." He was both mentor and inspiration at Samsung, with self-discipline and resolve to make Korean companies match their Japanese counterparts in technology and growth. He was like Konsuke Matsuhita of Panasonic in some ways- keen on learning new technologies and bringing excellence and quality to the Korean peninsula. Companies in India and other developing countries can look to the experience of South Korea in making similar transformations in South Asia and beyond. ...

LyrArc Article Gist
In January 2020 employees met at a local Maryland bar to find out how they might salvage their careers in a 33 year old company that had failed to develop an approved vaccine, says this story in WSJ. Only months later following the coronavirus pandemic everything changed as in a miracle for Novavax. The company had to sell manufacturing assets at one point, and had enough cash for another 6 months just months before. By Feb. 2021 shares which had dropped to $4 were up to $229 and valuation which had declined to $127 million went up to 15 billion. Coronavirus has turned things upside down where newcomers are using previously unproven technologies and making them work in this pandemic. The persistence, perseverance and confidence of Novavax even in the most difficult situations shows how the right attitude can lead to remarkable results. Novavax vaccine can be kept in refrigerators for 3 months, and do not require very low freezing temperatures like Moderna and Pfizer vaccines. This is considered a potent weapon in the fight against coronavirus. Novavax says it can produce a couple of billion doses over the next 12 months beginning in April. Novavax has released data showing its vaccine is effective for protection against coronavirus. Results of late stage US trials are expected in March. ...

LyrArc Article Gist
The new administration of Lopez Obrador takes the first step in its efforts to to end the rampant corruption in Mexico that has affected previous governments, in this story from the WSJ.  Lobrador campaigned on this issue and won an overwhelming mandate. Mexico's finance ministry is conducting an investigation into dealings of the steel maker Ahmsa in the sale of a fertilizer plant to Pemex during the period when Mr. Lozoya was CEO of Pemex.  Mr. Lozoya led Pemex from 2012 with the election of President Nieto of the PRI party to 2015 when he was replaced as CEO as Pemex finances suffered and Pemex failed to anticipate a fall in oil prices.  Pemex paid $475 million for the fertilizer plant. Mexico's government says the plant was worth about $50 million. The Brazilian company Odebrecht is also involved in the transactions, according to this report in the WSJ. Ahmsa is struggling to operate under court approved restructuring. Twenty years ago it defaulted on $1.8 billion of debt. Similar problems have plagued countries in other parts of the world. In Malaysia a new government campaigned on this issue with a 90 year old Mahathir Mohamed returning to head the new government  following the election.  ...

LyrArc Article Gist
The influence of lobbyist on members of Congress just as the Obama administration, having studied the failure of the Clinton submitted healthcare plan try a different strategy of letting Congress come up with a healtcare plan. $133 million was spent in the second quarter alone by healthcare industry lobby interests creating headaches for reform efforts and the Obama administration.

LyrArc Article Gist
The euro has stayed surprisingly strong at 1.35 to the U.S. dollar in November 2011, in the middle of the eurozone debt crisis. One factor cited by analysts in addition to the interest rate differential is the repatriation of funds into the eurozone as European funds and banks try to prepare themselves for a worsening situation.

LyrArc Article Gist
The story of one Guatemalan immigrant. About 1.35 million Guatemalan immigrants or 10% of the population live in the USA according to the Central American Institute of Social and Dvelopment Studies, a think tank in Guatemala. Remittances at $4.2 billion in 2007 are ahead of coffee, sugar and other exports.

LyrArc Article Gist
Mira Patel provides this report in great detail on how Indians living in the UK have grown from a tiny minority of 30,000 before independence in 1947 with little recognition in the UK to a population of 250,000 by 1961. In the years after 1945 many of the Sikhs and Punjabis in the British Army stayed in the UK. Two more waves of migration followed one with the East African Indians coming to the UK and one with Sikhs going to the UK. Race Relations Act of 1968 and a bill in 1961 changed the nature of immigrants to more professional people and students to maintain racial balance. By 1971 there were 483,000 Indians in the UK. Even today with 1.4 million Indians in the UK this forms only 2.5% of the UK population. Rishi Sunak and Priti Patel have important positions in the 2 year old Boris Johnson government yet too much can be read into this. Both are not deeply popular among the British public. Penny Mordaunt is the favorite at the grassroots of the Conservative Party. When one looks at the immigrant communities of Indians in the UK at one time in the 1880's only one MP Dadabhai Naoroji was in the British parliament. Today there are several ministers but mostly in a collapsing Conservative party administration of Boris Johnson. By comparison most of the Indian community migration in America has developed deeper roots and merged with the consciousness of the American society and public. Sunak and Patel are seen by most of the Labour grassroots as elitist, a kind of Macaulay class that Mira Patel describes. Macaulay a Britisher of the period of the British East India Company described the need in 1800's for a class of Indians "Indian in blood and color, but English in taste, in opinion, in morals, and in intellect." This Indian diaspora is a distinct Indian entity which is why it is a class of Indians that Macaulay coveted says Mira Patel, but one that she says forms leaders in Britain not leaders in India. In some ways the US is different with less of the class society that the Empire and the Tory party represent. And in this way formed under a country that fought this very same Empire the Indian community in the US seems to have integrated into the vision of Washington, Jefferson and Lincoln in ways that cannot be imagined in Britain or in Europe. ...

LyrArc Article Gist
Both the Tories in Britain and the Democrats in the US were caught by surprise by the sudden surge after the pandemic of illegal migrations flows in 2023-2024 which dropped to all time lows in 2019-2021 with the covid lockdowns. Tories with factional infighting and Democrats falsely believing they were virtuous humane could not take effective decisive immediate action costing them the defeats in 2024. The size of the illegal migration problem to the UK was underestimated in 2023. Tory rhetoric alone failed to convince the British public. In the US Biden not confronting it head on also failed to reassure the American people as the US Border also meant destructive Mexico/China fentanyl flows. Even today the action proposed falls short and new US bipartisan legislation is needed to make it the law of the land, closing three decades of stealth in immigration policies. ONS now estimates that it missed 166,000 people. The real figure for the year ending June 2023 for net migration was 906,000 not 748,000 as previously estimated. In the year ending June 2024 this figure for net migration was 728,000. Labour party under Keir Starmer made setting up the new structures for tackling alarming rise in migration the top priority in 2024. That lesson was not learned in the US and the issue not confronted head on to win public confidence- the Biden support for Republican Senator Lankford's legislation on illegal migrants and the border came late in 2023 and the issue was left to fester for 2 years eroding public confidence. In the US the issue of illegal fentanyl flows at the US Border and from China makes the Border and China relations issues that required effective and immediate action overriding everything else. In the end Tories confusion and internal factions, other controversies, led to lack of vigilance and lack of effective action as net migration deceptively hit lows of 254,000, 111,000, and 254,000 in the pandemic years 2019, 2020, and 2021, only to surge tremendously to 634,000 and 906,00 in the years 2022 and 2023.  Labour's Starmer took action to make it No. 1 priority in the platform going into the 2024 election winning public confidence. A similar surge in migration happened in the US after a deceptive slowdown in the pandemic, compunded by Venezuela and central American states collapsing. ...

LyrArc Article Gist
Country living has become an attractive option during the pandemic. Thousands of city residents are fleeing cities such as New York, Paris and London to be closer to nature and more spacious accommodations than the small city apartments. In the U.S. 39% of city dwellers in one Harris poll said the virus made them think of moving to less crowded areas. In France 38% of potential home buyers changed their searches to look further away from big cities as they looked for more room and garden space. Remote working and many professions encouraging their workers to work from home during this pandemic are giving momentum to this trend. Another factor is the cost of living in the city after the drop in income. And the risks in public transit, getting around in traffic jams, congested areas making social distancing routines difficult increasing chances of infection, are all part of the story. New York, Paris, London and Madrid are the hardest hit cities in the world. This extends to Beijing and Mumbai, Sao Paulo which are also hard hit by the virus. ...

LyrArc Article Gist
The use of fast track procedures under 510 K, for approval of Ren-Gen's Menaflex product to treat knee injuries. Under 510K rules for fast track no clinical trials are required, because the product is similiar to already existing products. Menaflex does not have asimiliar product, yet the FDA allowed Menaflex to be treated as fast track. The closest is orthopedic surgical operation, which is quite different. Menaflex is a C shaped pad used to repair a torn meniscus, a rubbery substance made from cow collagen that that acts like ashock absorber between the knee bones. Their is a booming market for meniscus repair among sports athletes. In fact originally Ren-Gen did not even apply as fast track, but only afte its clinical trials ran into trouble, did it try for fast track, which was turned down several times. At which point Ren-Gen got Democrats Senator Robert Menendez, Rep Frank Pallone, Chairman of the Health Subcommittee of the House Energy and Commerce Committee, Rep Rothman of Hackensack where Ren-Gen is based, and Senator Frank Lautenberg to intervene. At this point Senator Menendez and the others wrote to the FDA Commisssioner Dr Von Eschenbach, and Menendez spoke to the Commisssioner personally on the phone. After this intervention things started moving in Ren-Gen's dirtection, bypassing the FDA staffers who had reservations, and a special panel was appointed that again excluded anyone that had reservations, in an unusual procedure, which approved Menaflex. Now Congress and the Obama administration are being asked to review the whole process the FDA uses for medical devices because of the controversy this has caused about what is seen as unfair influence of companies in FDA approval process. Menaflex say those who had reservatoions faces alot of pounding and wear and tear between the knee bones and its safety and effectiveness needs to be proven before approval. It has been approved in Europe for afew years, but only 2800 patients have used it in Europe, only a small proportion of patients, and not enough is known about its effectiveness and any issues. ...

LyrArc Article Gist
Abe's new team in Japan. Yasuhisa Shiozaki one of the more aggressive appointments signalling change balanced by appointments of older men from his faction in the LDP. Hiroko Ota, a protege of Mr. Takenanka becomes economy minister in charge of the council on Economic and Fiscal Policy. Aso continues as foreign minister and will try to smooth Japan-China relations.

LyrArc Article Gist
NYT's Thomas Edsall does a great service to America by pulling together different views on the causes of the alienation of the rural population in the US from the Democratic party. The situation in Wisconsin with Ron Johnson winning in that state on the back of resentment of the rural population is shown. It all started say experts with the the so called Third Way that turned out not to exist of Tony Blair in Britain and Bill Clinton in the US that quietly accepted the Reagan view of the world and moved the Democratic party in a different and unknown direction. Obama made things worse by embracing Tech and tech companies into the Democratic party, and ignored the concerns of rural and agricultural parts of the US. The Obama period continued the Clinton policies of letting China takeover America's position in manufacturing, and allowing the offshoring of much of American industry to China. By not closing the chapter of America's wars in Afghanistan and Iraq president Obama lost many critical years. Mr. Biden now has the extraordinary challenge of not meekly accepting what has happened knowing that it is not in the spirit of the party of FDR and Truman, that the Democratic party will stand or fall with the common man, that it will take some time to recover from these missteps, that it is in the interests of America and the American people, and for what America stands for in the world. It is all embodied in what Carl Sandburg once wrote- "The People, Yes!" ...