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A series of voicemails and emails in court documents now disclosed, show that AstraZeneca tried to suppress findings about diabetes after effects in taking its psychiatric drug Seroquel. In an August 15, 2005, voicemail sent to company salespeople an employee Christine Ney, followed up on a"weight and diabetes sell sheet" they had recently sent. It said that the salespeople should assuage doctors' fears about their patients' weight gains, telling them that the data did not show any causal link between diabetes and the drug. "Our objective is to neutralize customer objections to Seroquel's weight and diabetes profile", Ms Ney said in the voice mail message. She instructed representatives to "refocus the call" away from diabetes to the drug's tolerability. While all this was going on and years before this, Astra Zeneca concealed a drug safety expert's own assessment of Seroquel's relation to diabetes. In a 2000 position paper about the safety of Seroquel sent to Dutch regulatory authorites, an AstraZeneca doctor named Wayne Geller wote that there was a relationship between the drug and diabetes. He wrote " there is reasonable evidence to suggest that Seroquel therapy can cause impaired glucose regulation including diabetes melliutus in certain individuals."...

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Peter Eavis, in the Heard on the Street column, says something similiar to what Krugman said when the Geithner plan (for troubled assets to be bought by private investors with cheap money from the government,) was announced March 23, 2009. His point is similiar to Krugman's in that if the market is experiencing just ashortfall in confidence and liquidity Geithner's plan might work, but if the underlying properties are not worth that much, the government engaging in agame of price support can't really win. The securitizztion of mortgages ocurred in a period of easy money. Now that that period is gone the basic underlying structure that supported it is gone. With more job losses at the rate of half amillion a month does anyone think the government can make the underlying mortgages for these securities profitable even with the government putting in its money to leverage the returns? He is right in pointing out that investors would need to build abig margin or error and will likely bid well below what banks are willing to sell at. CreditSights projects collective losses of the 4 biggest US banks through the end of 2010 of $250 to $450 billion....

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Questions about the wisdom of Exxon's moves against Venezuelan oil company Petroleos de Venezuela- taking it to court for taking a majority interest in 4 big oil projects managed previously by large western oil companies. Responding to Venezuelan public concerns about the deterioration in the oil production and development in Venezuela, President Chavez is negotiating with Shell and Total to bring in technical expertise and capital from western oil companies, while working at the same time with Petrobras and other national oil companies from China and Russia to develop its heavy oil assets. With Brazil facing capital needs for its own huge offshore Tupi oil field discovery, the $10 billion that is needed for developing the Carabobo oil field in the Orinoco will have to be financed with other foreign help and expertise. Petroleos Venezuela cannot rely solely on other national oil companies as it had thought it could do before. With things changing in Venezuela, and possibly even a new more friendlier government in future elections, has Exxon found itself on the outside when the European oil companies can build their presence in Venezuela?...

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The recommendations of the President's Working Group on Financial Markets to be given today by Treasury Secretary Paulson. The Working Group includes the heads of the Federal Reserve and the Federal Reserve bank of New York, and the heads of SEC ad CFTC. The aim is to prevent the kind of crisis in mortgages and credit from happening again. There are other private-sector advisory panels also at work with Treasury with one focusseds on credit rating firms and Congress is working on this also. Much of it does not require legislation and some of it can be implemented immediately. Regulators are asked to work more closely with the Financial Accounting Standards Board to revisit accounting issues and make sure exposures are properly reflected.They are asked to make their independent assessments and not to rely on credit raings firms. Fannie Mae and Freddie Mac are asked to work on raising more capital and reduce dividends to conserve capital. New licensing standards are supported for mortgage brokers. The question is whether new storms in the economy and credit and financial markets will make this look not enough considering the situation facing the economy and financial markets....

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Iraq's oil ministry wants to move ahead faster in developing its oil fields and will let foreign oil companies bid for contracts to develop 6 oil fields and 2 natural gas fields by end of 2008. About 40 foreign oil companies from USA, Europe, Japan, China, Russia have been approved for bidding on contracts. According to BP PLC statistics Iraq produces 2.5 million barrels a day, up from 1.9 barrels a day last year, but far below the 3.5 million barrels a day produced in1979. The Iraqi goal is to produce 1.5 million additional barrels a day, but obstacles are the lack of a hydrocarbon law which is not moving quickly, and the Kurdish region signing its own deals, and this announcement may be an effort to go ahead and not wait till a hydrocarbon law is passed and sign agreements which would be technical service agreements for foreign expertise for a fee. Oil revenues are helping stabilize Iraq and as security improves oil can be a big stabilizer with increased production and financing development and job creation and building infrastructure damaged during the war and infrastructure that never existed....

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Germany's industrial union IG Metall with about 3.6 million workers is asking for 7 to 8% pay raise for its members. Goldman Sachs Dirk Schumacher says a rule of thumb is that the final deal is about half a high as the initial demand. Last year the demand was for 6.5 raise and the end result was a 4.1% aise in mid 2007 and a 1.7% raise this summer. That deal ends in November. A look at the graphs for last year side by side showing inflation and pay increases from the Federal Statistics Office of Germany shows that even with the pay increases granted the CPI monhly data for Germany or the rate of inflation is running higher than rate of pay raises. The German economy is not doing as well but experts say that it can absorb these moderate pay raises without affecting the attractiveness of exports and affecting demand in Germany. If anything inflation has accelerated compared to last year so for German workers the situation would be more like the status quo or just keeping up with their current situation. ...

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Feldstein says that the $700 billion plan to buy impaired assets will not prevent an overshooting downward in house prices, as more people have negative equity in their homes, rising to 40% of all mortgages at some point; and leading to a cycle of foreclosure and further price declines. This will only decrease the value of the mortgage securities that Treasury seeks to take off the hands of banks. And without direct government help in form of lowcost loans, say 2%, the cost of capital for the government, for 20% of the loan upto $80,000; more and more homeowners will have negative equity in their homes. This will lead to more foreclosures as housing loans are not full recourse, so that only the house is lost and the homeowner can move to an apartment and carry on from there. Thw size of this program would be $1 trillion but it gives the government income from the loans made and these would be full recourse loans so the taxpayer is protected. In Feldstein's view the current plan does not address declining house prices which is the root of the problem. ...

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In his essay on the oped page of the WSJ Bernanke says: "history teaches us that government engagement in times of severe financial crisis often arrives very late, usually at a point at which most financial institutions are insolvent or nearly so, and in these conditions the consequences and costs of inertia and inaction can be staggering." Bernanke clearly is a student of the Great Depression and has learned the lessons from that catastrophic crisis. He pushed early for Paulson to take the case to the American Congress, and he had early on called for an injection of capital into the banks for ownership stakes, something the Bush administration ideologically resisted. Now that $250 billion is being injected into banks as part of the $700 billion rescue effort, and a global plan is being shaped after the Gordon Brown plan in the UK, it is possible for Bernanke to say that serious efforts are being taken that meet the severe challenges posed by a freezing up of credit markets wordwide. After some missteps and the help of Gordon Brown's initiative in the UK, there is reason for confidence even in the face of what Bernanke calls more " inevitable setbacks."...

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Amy Chua interviewed in her office on the Yale campus. She relates democracy to ethnicity and has a book on this. This creates complex situations which need to be recognized and democracy has to be crafted for that special situation. As for instance Stiglitz describes the succesful effort by Malays under Tunku Abdul Rahman in post independence Malaysia to make provisons for economic protections for the native Malay peoples within the democracy crafted for Malaysia. Carothers of the Carnegie Endowment points to post colonialism experiences in some countries. " Many of the problems that countries face are the legacy of European colonialism not United States policy. Why should democracy get blamed for failed empire?" In these countries their own unique situation, history, culture, time and place requires crafting and using free markets and democracy ideas with a healthy mix of measures the state can take to protect the weaker interests in society to achieve economic progress and fair distribution of benefits to all parts of society in the same way that the US and European countries with their different situations are doing in their individual circumstances. ...

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In a major policy move India's Modi government makes major changes for foreign investment in India. In different sectors, pharmaceuticals, defense, civil aviation, and retail stores, the move is designed to attract investment and create new jobs. Foreign investors can now take 100 percent ownership in defense, civil aviation, and food products sectors with government approval. In pharmaceuticals foreign investors can take upto 74 percent ownership with no government approval needed. In retail stores, such as for Apple and Ikea, the rules offer new incentives. From now on the requirement that Apple and other companies buy 30% of their supplies locally for single brand retail stores will be relaxed with a 3 year exemption on local sourcing, which can be extended to 5 years if the products sold are "state of the art" and "cutting edge technology," according to a government announcement. The changes were made by executive order. Apple CEO Tim Cook visited India and lobbied for this change recently. In combination with a national GST goods and services tax to be passed in July 2016, which is to be instituted nationally to replace a old set of state by state requirements and taxes, the two changes could have a bigger impact than the 1991 reforms that moved India away from a socialist managed economy. Poor job report numbers may have increased the pressure for taking action. In the defense sector the earlier change to allow 49% ownership had resulted in few new proposals. The changes in foreign investment rules also follows the resignation of the head of the central bank, Raghuram Rajan. ...

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Unknowingly many people have ownership in gun manufacturers through their pension funds. Pension funds for public employees in Florida, Texas Wisconsin and Ohio have stakes of less than 1% in American Outdoor Brands, formerly Smith & Wesson, the manufacturer of AR-15 semiautomatic rifles used in mass shootings at schools and other locations. Even a reputed fund such as TIAA representing teachers has small stakes in this company, this report in the NYT shows. New Jersey is one of the states cutting out investments of state pension funds in gunmaker companies. New York state still has small positions in its teacher pension funds in these companies. AS this NYT report shows it is through the use of  broad stock indexes that pension funds end up owning these stocks even when they have not specifically picked out such stocks. Equally or more alarming as reported here is that funds such as Fidelity and Vanguard own large stakes in the gunmaker companies. Fidelity is reported as the top shareholder of Vista Outdoor, with 15% of the company, through actively managed funds.  Vanguard has a 9.5% stake in Sturm Roger, and a 8% stake in American Outdoor Brands. Black Rock and Capital Group also have stakes in gunmaker companies. This points to a larger culture problem in the U.S. as financial companies see this as " a social issue" whatever that is supposed to mean in the minds of investment managers, when it is really an everyday issue for parents and children. In a culture prevalent in parts of the country and American society that sees something as basic as guns in schools and other public areas as "social change" a spokesman for Vanguard can quietly say that "mutual funds are not optimal agents of social change," without arousing a response. ...

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Huge dust clouds that can change climate and which are miles and miles long and which float all the way from China to the west coast of the US and how it affects the climate.

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The growing number of women in their 40's who are childless, one person homes, "child-free" adults, higher rates of divorce, are not limited just to Western Europe, the U.S. and Japan. This is spreading rapidly in lower income countries in the Arab world and Asia also. In Europe the progress is relentless. With divorce rates higher and fewer women marrying, the probability of a women of reproductive age getting married in Belgium is about 40%, and divorce at about 50%, according to Eurostat. So that the probability of women getting married and staying married is about 20%. This is true of other European countries also. There is a huge increase in "child-free' adults, men and women choosing voluntarily to not have children. The proportion of childless women in their 40's is highest in Berlin and Hamburg, nearly 33%, about 25% in Italy, and 20% in Sweden. One person homes are increasing in Western Europe, with about 32% in Europe and 45% in Denmark, not from aging alone as in Denmark as many as twice the number of one person homes are under age 65 than over 65. The UN population Division's "World Marraige Data 2012," shows that places like Morocco, Libya, and other parts of the Arab world are also experiencing these trends, with income and schooling levels much lower than in Europe and the U.S. These trends are now worldwide and affecting traditionally conservative societies like China....

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President Trump pushes forward with a deal with Mexico so that it can be signed before the new Mexican administration of Lopez Obrador takes over. This means leaving Canada out and having a separate deal with Canada later on. Mr. Trump sees negative connotations in the term NAFTA and would like to call it the "United States - Mexico Trade Agreement." Terms for Canada to join the agreement would be tougher and the pressure on Canada to strike a separate deal was increased with Mr. Trump saying there could be tariffs on imported Canadian made cars. Mexico has accepted revisions to NAFTA that make it harder for Mexico to challenge U.S. trade penalties. Mr. Trump's negotiating position is based on his conviction that the eagerness of other nations to sell in the U.S. market gives the U.S. a lot of clout. Mr. Trump also faces pressure from within the Republican Party to show results not just by imposing tariffs and playing hardball on trade but to come up with new trade deals. Steps taken by Mr. Trump were to impose tariffs of 25% on imports of aluminium and steel, and 25% tariffs on a list of imports from China including solar panels. President Trump hopes to get support from Democrats by including provisions that support trade unions in Mexico and higher wages in Mexico. The provisions also require higher wage labor in the U.S. to build the required U.S. content and are designed to support American jobs and wages in the auto industry.   ...

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Most experts are critical of president Trump's use of language "fire and fury" to North Korea for its missile tests and threats to the U.S.  The closest one gets is the language used by Harry Truman during the bombing of Hiroshima and Nagasaki with nuclear bombs.  Mr. Feaver, a national security expert and Senator Cardin say Mr. Trump is using the same language that the north Korean leaders is using and this simply raises the tensions. Feaver was adviser to President George W. Bush on the National Security staff. He says Bush's statement "bring 'em on" to Baath loyalists and militants targeting U.S. troops was a mistake, as well as some other Bush statements in the war against Saddam Hussein who Bush said he wanted "dead or alive."  Victor Cha, a former National Security Council official under president Clinton, says Bill Clinton used language that acted as deterrance to the the North Korean government when he said at the demilitarized zone in Korea, any attack would be "the end of their country." Cha sees Trump's language as a form of deterrence to avoid any miscalculation. Feaver says the language is dangerous, and the only way he can see it being thought out is that 30 years of diplomatic effort have left us with little improvement with North Korea, and the idea that lets try using the same language as the other side. Yet even here he sees it as escalating the rhetoric when nuclear missiles are involved. ...

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Nokia pins its hopes on China as it sees room for a third ecosystem after Apple and Android in the growing Chinese market.

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Prime minister Renzi of Italy says he is determined to push through changes that will let entrpreneurs hire and let go employees as needed. He proposes an agency to handle retraining of employees no longer needed by firms. He points out that he respects the role of unions, but that the fate of the economy must come first before the fate of the unions.

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Bishop Droge of the Evangelical Church Berln-Brandenburg, with over 1 million members, speaks to DW.com before the services at Kaiser Wilhelm Memorial Church following the Christmas market attack near the church. Bishop Droge reminds Germans that the church itself is destroyed from the war and still in ruins as a reminder of what violence and hate has done and can do. Not only is it a reminder of this, says Bishop Droge, it is a church of reconciliation, a reminder of reconciliation. In the rubble of the bombed out ruins of the Coventry Cathedral in England, the church's provost pulled out nails to form a cross.  The Kaiser Wilhelm church contains this "Cross of Nails." This he says is the message of the Kaiser Wilhelm Church, and the message that carries one through the difficult times, which itself were apparent before the Christ child appeared in that far away period because of the oppression at that time. A quietly stirring message from Bishop Broge that all Germans can hear. ...

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Prices of natural gas in the US have risen 93% since August 2007 and as global demand continues prices are expected to fuel inflation in the US. Producer prices were up 1.1% in March according to Labor Department and natural gas prices contributed to this increase. Natural gas heats half of uS homes, supplies 20% of USA electricity and is used to make products from fertilizer to plastic bags. And demand from the US power sector is growing at 10% a year as natural gas is clean burning to produce electricity at power plants and preferrable to caol burning plants from environmental standpoint. With environmetal regulation and costs natural ga ma be preferred by plants for power generation. A revolution has ocurred in the way natural gas is cooled into liquid LNG and transported in LNG tankers so that places like Nigeria and Quatar can now ship to Japan and Europe. And LNG contracts are now written in less rigid terms so that supplies are not fixed over 10 year periods like before and can be diverted by suppliers to other markets where prices have risen so that when a nuclear power plant shuts down in Japan LNG supply can be diverted to Japan from other countries because of vastly higher prices in Japan. This also happens elsewhere last year a drought in Spain cut hydroelectric power and Spain turned to Algeria and Egypt which had already diverted supplies to Japan which paid prices twice as high as Spain, so Spain secured supplies from Trinidad a US supplier, which reduced supplies to the US by 31% over 2006. So this shifting global supply chain means shortages and prices in one place can reverberate all the way to the USA. Because of these and other reasons US prices are expected to go much higher by estimates from Barclays and Deutsche Bank....

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Stiff competition from Toyota, Honda and Hyundai in the minivan segment. GM and Ford exit this segment. Chrysler is trying seats that face each other, one child can watch a dvd and another play a videogame, placing a table 2 backrows of seats, and so forth family friendly changes in the new Dodge Caravan and Town and Country. But Chrysler sales are't doing so well to retail customers Of 211,0000 sales volume sales to retail of Dodge Caravan are about 126,000 compared to Honda Odyssey at 180,000 and then Toyota Sienna.

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Gujarat has a mortality rate of 6.2% compared to 2.8% for India. In total number of confirmed cases Gujarat comes fourth after Maharashtra, Tamilnadu and Delhi, with 21,500 cases. Most of the deaths are in the city of Ahmedabad and mostly at the city's large Civil Hospital. This report in the BBC says the deaths can be attributed to the reluctance of people in the city to go to the Government Civil Hospital because the quality of care is not good. Many patients come to the Civil Hospital only after failing to find a bed at other private hospitals. This means the patients condition is getting worse as he is not admitted rightaway but days afterwards when his condition has deteriorated. The weak health infrastructure of the state and the lack of quality care at the Ahmedabad Government Civil Hospital say experts has led to increasing number of deaths in Gujarat from coronavirus. Gujarat has been known for its improvements in transportation and roads infrastructure. This has not happened with health infrastructure. This situation is being seen also in China where not enough money is being invested for quality health care. Ahmedabad's Government Civil Hospital is one of the largest in Asia providing low cost care to a large population. ...

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UK economy declines 0.3% in April 2025 as exports to US decline. The UK is one of the few countries that reached a trade agreement with the US. Also important to note is that the UK economy grew by 0.7% in the 1st quarter of 2025. The US tariffs are a negotiating strategy says Treasury Secretary Bessent to get countries  including the EU and China to have a level playing field in trade with the US, and not take the US for a ride. This has some costs but they are temporary and we are all better off that world trade can now be on a firmer footing than the imbalances of before. Bessent for instance told members of the US Congress in the last 2 days that US inflation is actually 0.1% and has come down, the 10 year yield in the US bond markets has come down, and the US is managing this transition without cost increases. He said Walmart had increased prices after tariffs, Amazon and Home Depot had not, and he sees American buying from sellers like Amazon and Home Depot. The British economy will also benefit with the certainty that it now has a clear trade agreement under fair rules that will promote bilateral trade with the US. ...

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Treasury yields went down as demand for treasurys went back up mostly from money market funds with nervous investors. Still it will be a few days befor the full effect of the Fed's action can be seen.

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Remarks by president Biden in Accokeep, Maryland, at the International Union of Operating Engineers Local 77, April 19, 2023 outlining his vision for American workers and for its economy. "I am pro-union because union workers are the best workers in the world. Not a joke. That's the God's truth. That is the God's truth. You are the best in the world. It's better  for them to hire you, because you get the job done, you get it done on time, and ultimately it costs them less when they hire you." "So I've said many times Wall Street didn't build America. The middle class built America. And unions built the middle class. That's a fact. Unions. One of the reasons I ran for president was to rebuild the backbone, the backbone of this country, the middle class, to grow the economy from the middle out and the bottom up, not from the top down. Because when the middle class does well the poor have a ladder up and the wealthy do very well still. And we middle class can get a shot. We do well as well." "And that's in clear contrast to my friends on the other side of the aisle these days. DIdn't used to be. Did'nt used to be, but it is now. For decades they've said the best way to grow the economy is from the top down- trickle-down economics. Well, growing up, I didn't see a whole hell of a lot trickle down on our three-bedroom house with four kids at our dad's kitchen table. You know what, Trickle-Down did'nt work for us, and it did'nt work for a long time." "And by the way it's not just what's been with MAGA Republicans. For the last three, four decades we have been losing ground. And you know- it's hollowed out the middle class, you know rewarding wealth, not work; rewarding companies moving overseas because they get cheaper labor. Look at all- a lot of you know- and maybe you come from neighborhoods and small towns, like Scranton, Pennsylvania, where I come from, or Claymont, Delaware- where there used to be a lot of pride, because we had businesses, we had factories that were working, operating. In Scranton, and Claymont, there were 4500 steelworkers. There are none today. And not only do you lose jobs, you lose a sense of pride, lose a sense of who are you. You begin to wonder. Does anybody see me? I mean it sincerely." ...