LyrArc Article Gist
On world tuberculosis day the work of Dr. Zarir Udwadia is acclaimed for drawing attention to a resurgent tuberculosis in India through a medical journal article in 2012 for untreatable TB. India has 2.8 million new TB cases annually, 100,000 being drug resistant, according to WHO. India relies on outdated diagnostic tests that miss about 50% of the cases and Dr Udwadia says India needs newer technologies including GeneXpert tests. TB can be easily treated at a cost of $5 with 4 drugs over 6 months if done in time. Wrong drugs, incorrect doses, irregular medication, lets the TB bacteria become resistant causing havoc- leading to taking of 250 injections and 15000 pills treated for upto 2 years and costing thousands of dollars, with the toxicity of the drugs levels creating risks of deafness, blindness, kidney failure, and psychotic conditions. Crowded conditions in slum areas act as an incubator of the disease and infection rates, with 20 people being infected by one patient alone. ...

LyrArc Article Gist
The commissioner of the Food and Drug Administration 2017-2019 and the deputy medical director of its medical device center, give their thoughts on how to setup a sentinel surveillance system that would help tackle coronavirus and future epidemics. The idea is to track an outbreak in real time, with results sent to central labs so that outbreaks can be contained early and the surveillance operates to isolate affected areas for treatment and quarantine. High quality data from specific locations in real time and testing to isolate small pockets of infection, with rapid and reliable diagnostic tools are critical parts of this system.

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Research on the human genes by Novartis researcher Dr. Rappouli has helped develop a vaccine for Meningitis B. In a unique collaboration with Craig Venter, the scientist who decoded the human genome, Dr Rappouli, an Italian scientist working for Novartis unit, Chiron Corp., describes his research effort and results to Jeanne Whalen of the WSJ in 2007.