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Pfizer and Moderna's plans to make mRNA vaccines in Africa, Asia or Latin America may take much longer than 2022. The solution to producing an mRNA vaccine in Asia that could be mass manufactured and distributed throughout Africa, Asia and Latin America is now at hand. Gennova based in India, is partnering with Seattle startup HDT Bio to attack the problem of temperature and scalability in manufacturing for a mRNA vaccine that acts as a global solution using India's manufacturing capabilities. Dr Singh who founded Gennova, says- "We wanted to solve the problem of the scalability issue, and the temperature issue. If we can solve these problems, we are building a solution not just for India, but also a global solution." Gennova received seed funding from the Indian government. Other companies in Brazil and South Africa lack the manufacturing capabilities or financing needed that exist in India. The Indian government has achieved an initial goal of one billion vaccinated in just 6 months. The next step for India in its health infrastructure buildup is a mRNA vaccine that is an improvement over Pfizer and Moderna vaccines that can be stored easily, adapted for variants, and manufactured in large quantity as a global solution. ...

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Berkshire new CEO Greg Abel 2026, Berkshire 2026 stock positions- Apple $60 billion American Express $55 billion Bank of America $25 billion, Coca Cola $25 billion, Chevron $20 billion, Chubb $10 billion. In addition GEICO wholly owned by Berkshire generates about $42 billion yearly in cash from premiums which can be used to invest in companies. By pursuing an affluent demographic American Express gets operating profit margins of 16% and return on equity of about 30%.  Apple has about 27% in net profit margin and 151% in return on equity in 2025. Because of the high affluence demographic of these two companies it offers a strong base for performance for Berkshire. The insurance company GEICO and its reinsurance operations offer a steady stream of cash. This  is the base on which Berkshire has done well over the last two decades. The efficient markets hypothesis moderate form for investors says that publicy available information is reflected in stock prices to a great extent except for anomalies and behavioural aspects. When investors use a basket of 1000 stocks reflecting the economy as Vanguard core index funds, the anomalies and behavioural aspects are less prevalent or cancel each other out creating a strong form of the efficient markets hypothesis in practice for investing discipline. Benjamin Graham, the mentor for all investment leaders would accept this as a way of securing investment gains without the vagaries and uncertainty in selecting stock positions. In 2025 the Berkshire funds achieved 10% gains vs the S&P 500 index which gained 17%, proof that the average investor can do just as well as the so called sage of Omaha, Warren Buffett. ...

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25 years in the making at a cost of 10 billion euros, the new speed train between Berlin and Munich cuts the travel time to under four hours. This cuts it down from six to four hours.

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Shabana Mahmood UK Home Secretary  says -UK "will do whatever it takes to secure our borders," as the Labour Party seeks to meet the challenge from UK Reform Party. Across Europe, in the Netherlands, Italy, France, Germany and UK public opinion is shifting for a tight immigration system. Shabana Mahmood plans to adopt some aspects of Denmark's tight immigration system for UK. Labour MP's in the Red Wall and in places in the Midlands and northern England see this as action needed to prevent UK Reform from winning in this region of England. This has one problem in that Labour has taken too much time to arrive at this point when opinion on illegal immigrants has shifted for many years starting in Denmark. Even Wilders movement in Netherlands is now three years old and DJT's in the US is in its second term going back to 2016 and in a new phase in 2025. One could say that patience is wearing thin among the people in Europe and the US with all forms of illegal immigration whether across the Rio Grande or across the English Channel or across the Mediterranean to Greece and Italy, or across Hungarian border to Germany.  ...

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A You.Gov poll taken for The Times in the last 5 days says 9 out of 10 Tory voters have decided who they will vote for as ballot papers went out this week. And 60% will vote for Liz Truss who has widened her lead to 34 points over Rishi Sunak. Tory party voters for the leadership by a majority or 53% say Boris Johnson should not have resigned. Only 41% say Boris Johnson should resign. Mr. Johnson supported Liz Truss, as do most of the cabinet.

When asked who can get Tories a majority in the next election Truss at 39% has a 20 percentage point lead over Sunak. From this it appears that if Tories themselves and not the cabinet had decided Boris Johnson would still be prime minister, and Liz Truss takes on the premiers role with the same style and spirit of Brexit that Johnson brought to the role and would consider Mr. Johnson as part of the close advisers.

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When do Democrats support Republicans? When do Republicans support Democrats? Arrogance for one thing, belittling your opponents, not having that humility and listening skills essential to govern. Carter belittled Ted Kennedy for challenging him, his chief of staff Jordan ignored opponents. Clinton spent too much time outside the country as Secretary of State lost touch with working class people. Trump demeaned other Republicans- Esper, Milley, Bush Sr and Jr. and most painfull of all Senator Lankford. Trump came across in the debate with Harris as arrogant and demeaning to Harris.  The hero today is Republican Senator Lankford who authored critical immigration legislation, loyalty to Nation. Profiles of Courage by John F. Kennedy was written in 1954, and covers Republicans and Democrats in Congress over 175 years who had the courage and humility to question the accepted views even at the risk of being set aside by a overzealous public.  ...

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Brazil's oil company, Petrobras, has 55.7% of voting shares controlled by the government. Petrobras's nonvoting shares make up most of the widely held stock, which has increased significantly in recent years. Petrobras is Latin America's largest publicly traded company with market value of $96.9 billion. Oil production by Petrobras is 1.9 million barrels a day, larger than Brazil's expected consumption of 1.85 million barrels a day for 2006. The policies of former President Henrique Cardoso are credited with making Petrobras competitive. Cardoso passed a constitutional amendment that allowed foreign companies to compete against Petrobras. And he put new managers from banking in charge of the company, leading to significant changes in how the company was run. With new deepwater drilling oil production increased by 12% a year during the Cardoso years 1997-2002. Under the Lula administration Petrobras has also reflected the government's social goals by delaying passing on price increases in gasoline and cooking gas and limiting the price increases. Under President Lula the CEO and senior managerial appointments for Petrobras have come from the ranks of his political party, the PT. Jos Eduardo Dutra, and Jos Gabrielli are members of PT. Under the Lula government Petrobras faced little competition from foreign oil companies and Petrobras dominates the Brazilian oil sector....

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US Defense Secretary Gates sees the Wiki discloures on diplomacy as not being as threatening as imagined by government officials and as described. These desriptions are "fairly significantly overwrought" is how Gates puts it. He says these types of disclosures ocurred back in John Adam's presidency and have continued, and the US can work with other countries even if these discloures can be embarrassing. Overall he says the impact is fairly modest.

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Jonathan Gruber, the MIT professor, who has done extensive modeling of U.S. health care systems. Gruber advised Massachusetts Governor Romney in crafting the health care law in that state. He also advised the Obama administration in crafting the health care mandate that requires all Americans to buy health insurance to keep costs down. Gruber estimates the number of newly insured Americans could drop to 8 million from an estimated 32 million if the Supreme Court strikes down the health care law mandate. The result he believes will drive insurance premium prices even higher.