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Some people experienced fever and headaches after receiving the Pfizer and Moderna vaccine which disappeared after 2-3 days after which they felt fine. This report in WSJ says people getting the vaccine still think its a lot better than getting coronavirus. About 85% of the people taking the vaccine did not experience severe symptoms of fever for 2-3 days.

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The need for a global response to a global problems not a lot of local solutions is the subject of this article by Dr. Larry Brilliant, who for 7 years 1973-80 worked with the World Health Organization to eradicate smallpox globally. 1. Action for a global response-The WHO can act as the vehicle for action globally-  restructure it and empower it to do the job. Put the right people in place who have the confidence globally. Set a new pandemic treaty and put it in place. 2.  Get a more advanced version of the mRNA vaccine which does not need a cold chain. India is reportedly working on one. Put funds and people in place for vaccine drives in poor countries.  Other action needed is learning from the situation in South Africa where the HIV patients are reported by Stephanie Nolan in NYT to have been more susceptible to mutations of the new variant. How can resources be put in place in poor countries so that patients in vulnerable populations get their medicines regularly, and are vaccinated. Overall how can these populations have the vaccine supplies needed- including ones without cold chain suggested by Larry Brilliant, potentially through vaccine work in India. Can international teams be developed with developed countries in Europe and US financing the effort and India offering its manpower and knowhow?   ...

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The new challenge of getting the public to support the vaccine efort and build better communication with people around the world about the benefits of the vaccine.

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Italy and France have implemented vaccine passes. The health pass in France has helped to reverse the trend of waning vaccinations. In the two weeks after the vaccine health pass was made mandatory in France for cafes, transport and restaurants, the vaccinations for second dose increased by 6 million and the vaccination for first dose increased by 5 million. In Italy vaccinations increased by 200%.

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Early analysis of its Phase 3 study for Moderna's vaccine shows that it is 94.5 % effective in preventing coronavirus disease, including severe disease.

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A German company BioNTech founded by Dr. Sahin, a son of Turkish immigrants, is based in Mainz. Dr. Sahin says it will be ready with a vaccine by December 2020 when it will seek regulatory approval. BioNTech is partnering with Pfizer of the U.S. and plans to have several hundred million doses ready by the end of this year, 1 billion doses of vaccine by 2021. 

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The Oxford vaccine manufactured and distributed by Astra Zeneca faced manufacturing problems in 2020. The company is fixing these manufacturing problems and plans to meet demand from Britain, the European Union, and the rest of the world. It plans to double vaccine monthly production to 200 million doses monthly by April. CEO Pascal Soriot says "Is it perfect? No, it's not perfect, but it's great, and tell me who else is making 100 million doses in February?" The Oxford vaccine has shown strong protection against severe coronavirus symptoms and is important in the fight against the pandemic. To tackle variants of the coronavirus the company plans to have another jab developed by autumn this year.

Britain and India are depending on Oxford vaccine to vaccinate large parts of the population. India has a second vaccine developed by Indian scientists at Bharat Biotech that is also in use.

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The U.S. FDA approves the Moderna vaccine which may start shipping by Dec. 19. The Moderna vaccine was found to prevent asymptomatic infections after the first dose, a very important way to control the spread.

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Serbia ranks high in the countries with successful vaccination drives. About 29.5 people of every 100 have been vaccinated. About 2.2 million doses of the Pfizer vaccine were bought in August 2020 followed by separate deals for the Russian Sputnik vaccine and the Chinese vaccine. Serbian prime minister Ana Brnabic says the success is a result of their approach to vaccination- "A health issue, not a political issue, negotiating with all, whether East or West."

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Joe Biden, US president says the US will have 300 million vaccine doses by the end of July. 200 million more vaccine doses, with 100 million from Pfizer and 100 million from Moderna are part of new finalized purchases by the Biden government in February 2021. Biden says vaccine supplies were in much worse shape than he thought after the last 2 months of the Trump administration led to distractions that affected handling of the pandemic. 

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The European Union has deals for 300 million doses of vaccine from BioNTech and Pfizer to be delivered soon. Germany is setting up hundreds of vaccination centers for first 3 months of 2021. Transport logistics are a concern. The Pfizer vaccine has to be kept at minus 70 degrees Celsius or minus 94 degrees Fahrenheit. Paul Ehrlich Institute is responsible for release of vaccine batches in Germany for rollout.  Good planning is essential for the huge task ahead.

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The problem facing Africa is whether vaccine supplies will run out before new vaccine supplies come from America, Britain and France. Only less than 1% of African people have been fully vaccinated out of a population of 1.3 billion people. US president Biden said America will provide 500 million doses of Pfizer vaccine to poor nations before the G-7 meeting in Cornwall, UK. Britain added 100 million and France 30 million doses. With new more transmissable variants out there Africa is in considerable danger today. The Delta variant from India has been shown to be about 70% more contagious than the Alpha variant from Kent UK. It is already the dominant variant for new cases in the UK. The new variants are now spreading in Africa. Cities such as Johannesburg, South Africa, and Kampala, Uganda are seeing a surge in cases. Another problem in Africa is that governments are increasingly reluctant to impose strong lockdowns because of the economy. Already it is believed that Africa's middle class has been severely affected during the last 18 months. ...

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Pfizer and BioNTech studies show 90.7% effectiveness of their children's vaccine.

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Two health service workers at NHS Britain experienced symptoms after receiving the Pfizer vaccine. NHS is told by medicines regulator that people with a history of significant allergic reactions should not be given the Pfizer vaccine.

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Contrast the slow US vaccine export response with that of India, Russia, EU and China. Only in May 2021 after India's daily Covid cases were close to 400,000 a day did the US make a serious offer of vaccines to other countries in need of assistance. U.S. president Biden says that 80 million vaccine doses would be exported by the end of June 2021. The WSJ says citing Airfinity, a London research firm, as of May 10 more than 333 million doses of vaccine were produced by the US and only 3 million vaccine doses were exported. Contrast that with the European Union which has shipped 111 million doses overseas one third of its total production, Russia which has exported 27 million doses.  India has exported 66 million doses according to the Ministry of External Affairs website as of May 17, 2021. This includes 4 million doses to Brazil, 4 million to Nigeria. Within its own region Bangladesh received 10 million and Sri Lanka 1.2 million doses, Afghanistan 1 million. Mexico received about 1 million doses. In Africa the Democratic Republic of the Congo which has suffered from many epidemics including Ebola virus received 1.7 million doses, Nigeria 4 million doses, Kenya 1 million, Uganda 1 million. Of the 66 million about half of it is a direct grant assistance and Brazil, Mexico, Morocco received all vaccine as grant assistance, 70% of Bangladesh's is grant assistance. The list on the Ministry of External Affairs site of the Government of India shows 95 countries including many of the most struggling nations of Latin America and Africa, bringing hope to countries which are struggling to hold onto hope for a better life beyond the pandemic. Sending help overseas through vaccine supplies is suspended for the moment but will resume in July after India has pulled in all of its pharmaceutical manufacturing industry under a government guided effort to go all out. Never has so much help bringing much needed hope gone to so many countries of the world in the twentieth or twenty first century from a nation that is struggling to meet its own needs. The US in pursuing a US first policy of vaccinating all its citizens has not taken into account the need to bring this evolving vaccine technology into the hands of as many qualified pharmaceutical manufacturers as possible. This in a rapid response to expand manufacturing capabilities to meet world wide demand. The risks of not doing so were not taken on early- the very same way the virus spread in January to March of 2020 can be repeated as people travel around the world particularly for tourism, business family reasons. This risk takes on anew dimension of contagious mutations of the virus which are 50% more- the Indian variant being 50% more contagious by some estimates than the UK variant, which itself was estimated to be 50% more contagious than the original one.  The result a pandemic that stretches out indefinitely unless billions of doses are made in a short timetable to beat the timetable of Nature through the coronavirus. India is doing this for the first time with plans to produce billions of doses by engaging the whole of the Indian pharmaceutical manufacturing industry in the effort in a rapid response so that July to December would see 1.2 billion people vaccinated. The US effort, the European effort is left to the individual effort of pharmaceutical makers in the US and Europe, not a government guided effort to engage the entire pharmaceutical industry of the US and Europe in a rapid response timetable of 2-6 months.  ...

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International aid arrives from the UK, France, US, and the European Union, as India faces a surge of the coronavirus in April 2021. A flight with oxygen and ventilators arrives from the UK. The EU is pooling resources, France is preparing flights with equipment. The United States Biden administration says it will release some of the 60 million doses of Astra Zeneca vaccine to India that remain unused in the US to address vaccine shortages.

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Research on the human genes by Novartis researcher Dr. Rappouli has helped develop a vaccine for Meningitis B. In a unique collaboration with Craig Venter, the scientist who decoded the human genome, Dr Rappouli, an Italian scientist working for Novartis unit, Chiron Corp., describes his research effort and results to Jeanne Whalen of the WSJ in 2007.

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FR24 talks to French epidemiologists and provides answers to questions asked by vaccine sceptics.

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Vaccine passports are seen as discriminatory in Britain and by Boris Johnson. The goal is to get the entire population vaccinated. To have vaccine passports when only some segments of society are vaccinated creates a two tier society, it is felt.

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The company that is marketing the Oxford vaccine shows double digit growth mainly from new oncology drugs. Astra Zeneca partnered with Oxford University for distribution of the vaccine on a nonprofit basis for the pandemic in all parts of the world.

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Dr. Andrew Pollard and the invention of Covishield vaccine at Oxford University in Britain in 12 months, that has saved the world, with 2.6 billion doses given. It is in its final act says this report in The Guardian with 3 billion doses to go for the 3 billion people in the world that have not received a dose. Billions of people in India, other Asian countries, Latin America and Africa depend on this vaccine during this pandemic.

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Some local governments in China are making vaccination mandatory. China is setting a goal of getting 64%  of the population fully vaccinated by the end of 2021. In European Union countries mandatory vaccination by country or region is now being put in place to fight new coronavirus variants that spread faster in the population. The reopening of economy, business and tourism is increasing the risk from variants in summer 2021. The mandatory vaccination is a way to increase the percentage of the population that is vaccinated. Getting younger people who lag behind to get vaccinated is important to protect the percentage of the elderly population that is still not vaccinated. There are risks also to the younger population as seen in previous waves of the pandemic. The initial hesitation to make health pass showing a person is vaccinated mandatory was because only a small fraction of the population was vaccinated in Europe. Now that over 50% are vaccinated in most EU countries and UK, that hesitation thinking that it is discriminatory to those people who did not have access to vaccines no longer exists. Ample vaccine supplies and the misinformation spread about vaccines are making action on health pass necessary to protect the overall population. National governments in France, Denmark, Austria, Greece, and local governments in Germany, Portugal and other EU countries such as Ireland, Italy, see the danger from coronavirus variants that spread quickly as too big to take any risks a second time. ...

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 Turkish German scientist Ugur Sahin who invented the mRNA vaccine for coronavirus is interviewed by Der Spiegel. He sees a new world of pharmaceuticals from this invention, with the first treatments of cancer.

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Dr. Anthony Fauci warns against anti-science, anti-vaccine feeling in the U.S. and other countries.