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The EU negotiator Mr. Barnier makes a concession on the Irish backstop which was already previously rejected by prime minister May. May says Mr. Corbyn of the Labour Party, that he was not really interested in finding a solution, and has given only one hour for talks in five weeks. The Irish prime minister Varadkar says May has not offered any solutions for Brexit. May says she will give parliament the chance to vote  for an extension of the March 29 date under Article 50 or decide if it wants a no-deal Brexit.

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Global sales growth will be from developing countries as US sales slow down to the rate of a 4-5% growth, losing 1 percentage point and be at the level growth is in Europe. This growth will mean U.S. sales of 305 billion dollars in 2009 for pharmaceuticals. Next year two thirds of prescriptions will be generics, increasing from 50% in 2003. Forecasts from IMS. Also FDA is taking a tougher line in regulation. Top seven emerging markets will grow at 12 to 13% a year in contrast- from improving economies and greater demands for spending on health care.

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This report says Biden and other G7 leaders toured the Hiroshima Museum but does not say that they visited the East end of the Museum shown in an NHK documentary where most of what happened, of people who lived and died in Hiroshima on that day, are shown. It is not shown that Mr. Fumio Kishida is himself a cousin once removed of a 4 year old boy whose remains are shown at the museum. Mr. Obama also has not visited the East end of the museum according to reports. Lyrarc.com has suggested that the NHK documentary that was broadcast in Asia last week should be shown to G7 leaders if they have not actually seen that part of the museum that shows the lives of the people on that day. The point is not to see the dead as from one nation but as people who could be from any other nation in a different conflict with different countries, the responsibility of any one nation or of nations on opposite sides should not obscure the importance of seeing the dead as just human beings- without nationality.     ...

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EU Commission president Leyen announces Pfizer will supply EU with 1.8 billion doses of Pfizer vaccine to 2023. The increased supplies will include booster shorts to increase immunity. Another change is the new date for 70% of European Union population to be vaccinated, which is now advanced to end of July instead of end of September. With new waves of the coronavirus affecting Europe, and criticism of the EU's earlier effort in securing vaccine supplies, more urgency has gone into the new effort in 2021. Leyen told Pfizer CEO Albert Bouria- "If I may say so, engineer the mRNA in a way that it can adapt to potential escape vaccines," at a joint press conference. Leyen thanked Pfizer for its enormous effort in boosting vaccine manufacture and delivery. This will help accelerate the vaccination effort in Europe after the slow start in March and April of 2021. Bringing much needed optimism and new hope of a lasting recovery both in economic activity, health and in the mood in Europe, which can then spread from the US and Europe to the rest of the world. ...

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Opening windows and doors to let in fresh air is as important as wearing masks and social distancing to prevent coronavirus. In places where people gather and in homes it is important to let in fresh air so that there is new fresh air circulating in rooms 3-4 times for every hour. It is being used as a strategy in schools in Germany to bring in fresh air. Putting MERV 13 type air filters in central air conditioning and heating systems is important in offices, shops and other spaces. A complete redesign of the systems that are old is needed. There are 36,000 schools in the U.S. that have old failing systems of heating and cooling. It would cost $360 billion to change these systems if each system cost $10,000 which is on the low side. This shows that good intentions are not enough, new priorities need to be set and the old priorities which misallocated funds through existing capital allocation structures in the West coasts and East coast cities no longer serve the purpose of the Renewal of America.  ...

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About 40% of Americans are obese with BMI, body mass index of over 30. About 71% of Americans are overweight or obese with BMI over 25. This is a finding in a new report by the Centers for Disease Control and Prevention. This report does not mention a separate finding covered in the Guardian online newspaper showing less than 15% of Americans get the daily recommended intake of fruits and vegetables, crucial in preventing major diseases such as heart disease, cancer, diabetes. The cost to America for obesity related or weight related medical bills is estimated at $190 billion a year, in three years this would help renovate the aging U.S. infrastructure if people changed their habits and education was designed to help change the way Americans live. Even harder to understand is that only 2% of America's farmland grows fruits and vegetables, according to the Guardian report which says this would need to be 4% to meet the needs of the people in the U.S.. These are alarming facts and need more public awareness by this being getting widespread attention on the internet. ...

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The director of Vote Leave on Brexit referendum Dominic Cummings says Brexit could be a mistake for Britain. Asked if he thinks differently now, he says in a Twitter exchange cited in Britain's Guardian newspaper- "Lots. I said before REF was a dumb idea, other things shdve been tried 1st." Others are having second thoughts about the referendum, as shown here.

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Efforts by charity groups in Andalusia, Spain, to get supermarket chains Mercadona and Carrefour to donate food for food banks. Some of the food goes to rural laborers hard hit by the unemployment in Spain. Unemployment in the region is about 34%. Spain's overall jobless rate is at about 24.6%. More unemployed workers are running out of jobless benefits in Spain in 2012. The percentage of unemployed people in Spain receiving assistance declined to 65% from 78% in 2010.

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Analysts say that if Greek banks pass the European banks stress tests to be announced this week, the stress tests must not be rigorous enough.

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Andy Burnham of Greater Manchester on what Labour party needs right now in September 2025. Here is what he told Laura Kuenssberg of the BBC-  “I am concerned about the balance, and I think you know, we need to use the deputy leadership contest to discuss some of these things. In a time where the scale and the nature of the challenge we face is such as it is, you need everybody pulling together, all parts of the party pulling together. And that points to a party management style that is less factional and more pluralistic." “Labour MPs need to be, they need to listen to them more and respect them more. You know, they were the ones who, if you like, caused the change in terms of winter fuel and disability benefits. But you know, they shouldn’t be punished for that." “I think that’s what it needs, you know, we need to hear the voice of the party, the voice of the members, and then the voice of our communities behind that, particularly in the north of England, to counter that London centricity.” ...

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How to deal with Bush era tax cuts is a big issue dividing Democrats and Republicans in the U.S. If no deal is reached by Jan 1. taxes on the average middle income family would increase by $2000 in 2013. Median inflation adjusted income declined 8.9% to $50,054 in 2011 from $54,999 in 1999, and economic mobility has fallen. The Democrat's position is for Bush tax cuts to apply to incomes below $250,000. Peter Orszag of the Congressional Budget Office and Jared Bernstein point out that while this makes the tax code move in a progressive direction it also creates handicaps in providing a sufficient revenue base to support middle class spending programs down the road. According to the Tax Polcy Center, if Congress is unable to reach agreement and all tax increases go into effect Jan 1, taxpayers in the bottom 20% of income distribution would see a $412 increase in taxes compared to an increase of $633,000 for the top 0.1%. New York Mayor Bloomberg has supported eliminating the Bush tax cuts for all groups, saying there is no free lunch. Alan Krueger, head of the White House Council of Economic Advisors, says the trends caused by globalization and skill-biased technological change which have increased inequality are likely to continue or accelerate. ...

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The London based think tank Open Europe says the exposure from Greece puts the ECB's balance sheet at risk. A small 4.25% drop in the value of the ECB's asset holdings could wipe out the whole capital base of the ECB, according to Open Europe. The ECB holds at present 75 billion euros of Portuguese, Greek and Irish bonds on its balance sheet. In the last 12 months the ECB has increased its capital base to 10 billion euros. The decision to buy Spanish and Italian bonds increases the risk. The ECB loses money if the borrowing bank goes bankrupt or the collateral of the borrowing bank loses value. During the negotiations for the eurozone debt deal in July 2011, the ECB obtained guarantees from eurozone governments for the collateral it holds from Greece. This increases the need for the European Financial Stability Facility to take on the role of buying bonds of troubled eurozone countries.

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The growing popularity of rail trips in Europe as companies such as SNCF in France and rail companies in Austria and Germany increase investments in rail infrastructure. The idea is to cut the carbon footprint on short haul flights.Sleeper trains are also increasing in popularity with a new Austrian rail sleeper train between Paris and Vienna. Unlike earlier increases in rail travel this one is getting more support as rail as the potential of being less stressful, more interesting and as more investment is being made on rail infrastructure in Eastern and Central Europe. 

Much remains to be done in integrating the different rail systems in Europe both in infrastructure terms and in ticketing to customers. If this is done rail has serious prospect of becoming genuinely popular.

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This story in the WSJ is about pregnant Emergency Room doctors still working. These three doctors are in the University of Maryland Medical System. They have leave but are working because if all three were to take leave it would pose significant strain on their group and their colleagues.

They have to reuse their respirator masks for a week till they are soiled and visibly damaged says this report in WSJ, which should be unacceptable in America. The risks they take are also unacceptable in the face of so much happening at hospitals. How long will this go on in hospitals across America with shortages of basic protection equipment for healthcare workers putting their lives at risk is what everyone is asking.

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A new $490 billion aid package in Japan is designed to help families and small business. Families with small children will get $900 per child and small business will get $22,000 each if they can show they were affected by the pandemic. Wage increases for nurses and care workers. Economy minister Yamagiva in the new Fumio Kishida government says this aid will "bring security and hope to the people by rebuilding the economy." Japan is following the US by providing aid to the people and business to help rebuild after the lingering effects of the pandemic. In the US president Biden is expected to pass a $2 trillion package including help for child care, paid leave for caregivers and mothers, other aid, and a big investment to tackle climate change.