LyrArc Article Gist
The expiry of pandemic aid programs and the cost of living increases in housing and food, medicine, have increased poverty in the US and affected the middle class and lower working class struggling to make a living. This is an issue for Biden-Harris to tackle upfront.

LyrArc Article Gist
Shorter work hours can provide time for yoga classes, time with children, travel overseas, and other activities for a healthier and more satisfying life. This report in WSJ shows people in different professions from medicine to environmental engineering taking a different approach to life. After the pandemic there is a rethink of what is a better way to work and combine work with attention to healthier living. Healthier living provides the concentration power that enables doing a lot more work in fewer hours creating a new way of working with time for healthy activities outside work. WSJ shows how this works in the lives of 5 workers and their families. For many workers it is possible to earn close to what they made with longer hours by utilizing the time more effectively, with all the added benefit of healthier lives- this adds up over the years reducing many of the health problems that come from neglecting healthy activities during prime work years. 

LyrArc Article Gist
NYT reports from China show how China is handling a complete U Turn on how to handle Covid. Most pandemic restrictions are lifted, and people can now recover at home. A rising number of infections and China is now open to bring in western medicines. It is seen as a boost to the economy. Even the government officials are wondering how to shape the new narrative. It shows the flexibility of the leadership in China and the willingness to learn from new developments in dealing with the pandemic. A similar step was taken by Democrats in the US as they relaxed restrictions in line with new evidence that was coming in with milder strains of the virus.

LyrArc Article Gist
Two U.S. botanists coined the term "plant blindness" for the inability to see or notice the plants in one's environment. Limited interest in plants leads to an under appreciation of plants and their value in environmental health and in medicinal research.

Plants and trees are essential to an healthy urban environment. And 28,000 plant species are used for medicines of great value for health. This BBC article looks at the ways humans can increase their exposure and awareness of plants and green environments around them.

LyrArc Article Gist
A major British and Indian collaboration and scientific achievement of both countries is not given the recognition it should get because of mismanaged communication of the results of clinical trials. Tom Whipple science editor of The Times says do not make the mistake of thinking oh Pfizer vaccine scores a 9 out of 10 and Oxford's a 7 or 8 out of 10. Pfizer vaccine says it 94% effective. But this is only part of the story. It is the first exam paper in a long number of exam papers and the final score will require scoring them all. "Oxford vaccine is complex, and we are happy with the complexity," says Adrian Hill, Oxford researcher and head of the Jenner Institute. It is not highly unusual in this complex field for a half first dose to work better than a full first dose in a two dose vaccine treatment. This happened with the Oxford vaccine. As a result the study results were harder to communicate. This happened by accident. Much of medical research and much of medicine's biggest breakthroughs in the last 200 years happened by accident, as one researcher looked for something and accidentally discovered something else profoundly useful. Whipple's points are turning out to be true now that Britain's medicine regulator has asked that Pfizer vaccine not be given to people with history of allergic reactions after 2 NHS workers had strong allergic reactions. A lot of questions remain for all vaccines. How long will the protection last? WIll it prevent transmission of coronavirus? Are there any other complications? Which vaccines can work without ultralow refrigeration storage? Ahead lie the prospect of billions of doses. Two are in final stages in India including Bharat Biotech request for emergency authorization. Johnson & Johnson has a competing one to Pfizer's in the U.S. As many as 30 are being developed in India and 100 around the world. Countries like South Korea say they will wait to find out which one works best and where cost overall combined with benefit is attractive. Some of the vaccines are coming out only weeks apart. The early ones could stumble, if something was missed. ...

LyrArc Article Gist
Issues of work-life balance are growing for doctors as more doctors ages 40-54 years face burnout or negative effects on health. Nearly half of doctors in the U.S. 40-54 years of age in a survey of 15,000 physicians report feeling burned out from work hours and administrative tasks. Younger doctors 25-39 years, and older ones 55-73 years also reported high rate of burnout at 38% and 39%. Overall for all physicians about half of all physicians said they would take a substantial pay cut to get a better work-life balance. What this survey and report by Medscape shows is that no age group, career stage, gender or specialty is immune to this problem, says Colin West, professor of Medicine and researcher on physician well being at the Mayo Clinic.

LyrArc Article Gist
Bharat Biotech and Biological E. are two companies developing vaccines in India. Bharat Biotech has asked for emergency authorization for use of its vaccine. Other Indian companies that have asked for emergency authorization are Pfizer India and Serum Institute of India. The foreign envoys will be flown to Hyderabad to be briefed on the vaccine readiness at Bharat Biotech and Biological E. In all 30 of 100 vaccines under development are being developed in India. India is a pioneer in vaccine development and manufacturing. Because of its huge population of 1.5 billion for India and Bangladesh, India has from the early years after independence in 1947 pursued a course of developing its own R&D and manufacturing of pharmaceuticals and vaccines, so that the large population can have access to medicine at a low price.

LyrArc Article Gist
This report in The Times shows how Africa is tackling malaria by using modern methods such as drones. Drones are used in Ghana to send medicine to remote parts of the country. The rollout of the world's first malaria vaccine is taking place in Malawi, Ghana and Kenya. The Glaxo developed vaccine requires 4 doses over 18 months. Gavi is a partnership that brings UNICEF and WHO in partnership with private companies to  buy vaccines in bulk and distribute them where it is not affordable. Gavi supported 66 million vaccines in 2018 for children, yet about 20 million children in Nigeria, Congo and other parts of Africa lacked routine immunizations in 2018. UPS and health service workers are joining in the effort for administering this vaccine correctly.  Software that tracks the taking of the vaccines by children is essential for success and this is being implemented with Ghanian authorites. This report shows how it is done in Dateng, Ghana, a town of 800 people 3 hour drive from Accra.  ...

LyrArc Article Gist
Stevis and Steinhauser talk to ordinary Greeks as they face pharmacies running out of imported medicines and the prospect of returning to the drachma.

LyrArc Article Gist
Over the last 5 years 2021-2025 Americans who are more excited than concerned about AI has dropped from 18% to 10%, and Americans who are more concerned than excited has grown from 37% to 52%, in Pew Research surveys. Showing that self-interested tech companies such as Microsoft and OpenAI, Google are making loud claims for AI that do not reflect the views of the American people as a whole in 2025.

Americans by large margins in Pew Research believe AI will help in day to day tasks from weather forecasting to inventing new medicines. And by large margins of 40% Americans think AI will hurt ability to think creatively and form meaningful relationships and by 20% will hurt for making difficult decisions. This shows Americans -similar to people in China as reported- believe in using AI for ordinary day to day routine tasks, and are wary of AI and aware that AI's usefulness is limited to such routine tasks only.

LyrArc Article Gist
The suicide of celebrity chef Anthony Bourdain who had a popular television program, brings new attention to the increase in middle age suicides ages 45 to 64 in the U.S.  The CDC figures show a 60% increase for women and 37% for men between 2000 and 2016. A clinical instructor in psychiatry and medicine at Cornell, Ms. Boardman says life satisfaction is low at this age,a dip in satisfaction called the U curve. A 2016 study in the American Journal of Preventive Medicine  shows stress factors as problems with intimate partners job/finances, health, family, and criminal/legal problems.  The demographic group driving suicide rates up is mainly white people without a 4 year college degree, who have done poorly compared to that group in a previous generation, say experts at Columbia University. 

Generally isolation and loneliness is also a factor, and social connections a big antidote to depression type stress.

LyrArc Article Gist
Considering the costs of obesity and the nature of the problem spread across the whole population of the U.S., only a nationwide effort will work, according to a consensus of experts in a report by the Institute of Medicine.

LyrArc Article Gist
Criticism of the FDA's inability to exert pre-market quality control. Questions raised by a Professor of Pharmaceutical Sciences, about the FDA's inability to detect quality issues in manufacturing. After the J&J recalls for childrens Tylenol and other medicines, the FDA sent a warning letter to Perrigo, a company based in Michigan, that ships these children's medicines, about manufacturing violations. This includes ibuprofen tablets with metal shavings.

LyrArc Article Gist
Two studies now show that it isn't that coronavirus just takes away the infirm or elderly who would have died anyway this year or the next. It is taking people away who still had over 10 years to live. Professor Biggs at the London School of Health Hygiene and Tropical Medicine says this is is what is happening from the study he is conducting.

A paper by Scotland based researchers published online by the Wellcome Trust a London based foundation found the average number of years of life lost to coronavirus for healthy adults is 14 for men and 12 for women. Using data from Italy and UK on the kind of long term conditions in the general population , the researchers found that for those suffering from common chronic illnesses and cancer including multiple conditions, the researchers found that people of this type lost about 10 years on average.

LyrArc Article Gist
German Chancellor Merz says welfare entitlements are becoming a strain on the economy. The welfare entitlements growing in size puts huge strain on the budgets of US, Germany, UK, and France. Small changes in the Medicaid program in work requirements became politicized in the US spending bill passed in Congress. The size of the Medicaid program in 2025 is an example. Started in the LBJ administration it was $1 billion in 1965 covering 4 million people increasing to $10 billion covering 20 million people in 1976. 50 years later it covers 3.5 times the number of people at 71 million at a cost that is staggering of $900 billion. US population in the 50 years increased from 218 million to 342 million by 57% when the Medicaid population grew at 355% of 6 times the actual population growth showing that the country in some ways was growing much poorer and unhealthier and that other factors were also at work. As a percentage of the size of the economy  Medicaid growth was $10 billion when GDP was $1700 billion in 1975 or .00059% vs $900 billion when Medicaid is $900 billion  when economy GDP in 2025 is 30,000 billion or .03000 which is 50 times the percentage in 2025 vs 1975. At work in this is the ballooning cost of the way medicine is practiced in the US, and other factors.   ...

LyrArc Article Gist
Even the entry into the Philippines by Wirecard executive might have been faked- where there was supposedly $1.9 billion in Philippines bank accounts of Wirecard that are reported to simply not exist- says this report in the WSJ.  

It shows how flagrant activities in misallocating capital have become at a time when PPE supplies, healthcare equipment and medicines are hard to find during the pandemic. Hundreds of billions of dollars have not only been misallocated away from basic infrastructure, education and healthcare but also in many ways wasted. A kind of Dickensian "it was the best of times, it was also the worst of times." 

LyrArc Article Gist
The Institute of Medicine releases areport of the 100 health topics that should get high priority, as the Obama adinistration proceeds with a plan to $1.1 billion to compare the effectivenesss of treatments. Some of these areas for research are prostate cancer treatments, a surgical procedure called ablation, and others.

LyrArc Article Gist
Now that finance ministries around the world are trying to save their economies with trillions of dollars in aid packages their finances are stretched to the limit. The so called digital tax is not really a digital tax. And efforts to recover lost tax revenues in Europe are being opposed by the U.S. because tax levies by France go only to France, not the U.S. The U.S. Treasury or U.S. government or the American people would not turn down tax revenues that it normally gets when its finances are stretched to the limit with trillions of dollars for cornavirus leaving little for crumbling infrastructure and essential public health services, other services that determine quality of life in America.  This Washington Post report shows that there is greater awareness that the right approach is to pay taxes based on where revenues are located and by the number of users in each country. But the problem goes deeper than that. The coronavirus changes the entire perspective and take this back to roots. Companies pay taxes because it is the right thing to do. In Japan Panasonic's founder Matsushita felt that it was a national duty to pay its share of taxes as it too was sharing in the benefits provided by society- in the health, sanitation, education and transportation, parks, and hundreds of services provided by government. Once this is seen as dispensable or somebody else's problem, then these very services and infrastructure can be starved of capital. Coronavirus changes this perspective. People crave for outdoor spaces- who is going to maintain them and set up new spaces. People crave for not moving around on crumbling bridges, roads, subway systems. Who is going to provide them? People crave for good schools, community colleges. Who is going to provide them? People crave for good sanitation systems? Who is going to provide them? People crave for good public health systems. Who is going to provide them? Its just good common sense. Is it possible for common sense to be missing? It is- just ask people today, and it is good common sense to have good critical infrastructure such as sanitation, medicine, public health, and local manufacturing of medicine, yet economic experts and economic theories thought it made sense not to do this.  ...

LyrArc Article Gist
The Hindu provides this look at the life and career of European Union president Ursula von der Leyen. Today Leyen is one of the prominent leaders in the European Union, and leads the fight against the Russian invasion of Ukraine. Leyen has visited places destroyed in the Russian invasion such as Bucha and talked to refugees, mostly women and children She has stated on Twitter after proposing a complete ban on Russian crude oil to Europe- "we want Ukraine to win this war." After a mediocre performance as Minister of Defense Leyen took the position at the EU headquarters in Brussels, where her father had served as a civil servant. Her father was  elected as Minister President of Lower Saxony province after working at EU in Brussels. Leyen went to secondary school in Brussels. Studying economics at London School of Economics before shifting to medicine, getting her degree in 1991. She followed her husband to Stanford University, and after her return to Hanover in 1996 was elected to the state parliament in Lower Saxony in 2003. She joined Merkel's cabinet as Minister of Youth and Family Affairs in 2005, deputy leader of CDU in 2010 and Defense Minister in 2013. ...

LyrArc Article Gist
This article in The Guardian looks at the role of British authorites in the Empire in the 19th and 20th century that led to famines. Under Lord Lytton in the 1870's and in 1943-44 in Bengal there were famines that were worsened by British policy. Throughout the 19th and the first half of the 20th century India's energies were sapped and its poverty deepened by the British effort to extract wealth from India through commercial policy and taxation. During the Napoleonic Wars Britain used its Empire in India to finance the war in a way Napoleon lacked.  .As can be seen in the British Residency park in Lucknow  British authorites focused their efforts on the Treasury of the collapsing Empires in India whom they replaced. The people seeing tax territories shifted from one foreign authority to another stretching over four hundred years with little difference in development needs being met. After a period of self-rule which struggled with development after Independence in 1947, India's largest state Uttar Pradesh with a population of about 300 million, is finally bringing sanitation, water, roads, housing and medicine to all parts of the state. ...

LyrArc Article Gist
Already vaccination experts at the Baylor College of Medicine cited here say they foresee another wave of the coronavirus in the Southern US because of vaccine skepticism barriers to vaccination, and much of the population not being vaccinated. The percentage of the population in the Carolinas, Georgia, Georgia and Louisiana, that has both doses of vaccine is low. About 50% have had just one dose. In southern states Mississippi and Alabama the vaccination rates are much lower leaving large parts of the population unvaccinated. The widespread presence of the Delta variant in the UK and the R rate being between 1.00 and 1.2 in UK shows that the UK even with higher vaccination rates than the US is still facing a danger of another wave as it reopens.  The ominous aspect of this is that from just over 400,000 the vaccinations per day dropped to 316,000i n the US. This means there will be a period when vaccination drive is stalled while the reopening is fully underway with a new contagious variant twice as contagious as the original coronavirus. This leaves the US at risk of another wave, with the south and western US, younger people who are out more and unvaccinated, more at risk.  ...

LyrArc Article Gist
Holding tension in any position that does not have dynamic movement is isometric exercise. The British Journal of Sports Medicine has a study with research that shows this isometric exercise done with squatting on the wall (or with a ball against the wall) for support for 2 minutes repeated 4 times with rest periods of two minutes each time for total 4 wall sits, taking 14 minutes, can reduce systolic blood pressure top number by 10 mmHg and diastolic pressure by 5 mmHg. Jamie O'Driscoll the lead author of the study says this is useful for people doing aerobic exercise, and yet could benefit from the use of isometric wall squats. A clinical exercise physiologist at University of Michigan says isometric exercise works because contracting a muscle and holding that position reduces blood flow to that muscle, when you release blood flow increases to muscle tissue. It creates signals that tell blood vessels to relax more and create less resistance to blood flow. To do this wall sit find a wall to lean against and take a couple of steps forward, feet hip width apart and slide your back down the wall and your knees getting to a 90 degree angle gradually. This uses quadriceps, glutes, calves, all leg muscles and abdominal muscles. ...

LyrArc Article Gist
Eli Lilly is trying new methods to reduce time for developing new drugs for cancer and diabetes. One method is to complete trials for testing dosage and efficacy simultaneously saving 14 months. Two of 5 research units are focussed on cancer and diabetes and all departments turning molecules into medicine are located together. On Oct 23, 2011, the patent for $5 billion revenue schizophrenia pill Zyprexa expires.

LyrArc Article Gist
The drop in the value of the Turkish currency, the lira, hits ordinary Turks as it pushes up the price of food, medicine and other essentials. The lira has dropped by over a third of its value against the dollar in 2021. This is leading to a decline in living standards in Turkey, says this report in WSJ. President Erdogan is pushing an unconventional strategy to increase growth, by having the central bank cut interest rates as the value of lira drops sharply. This could lead to further drops in the lira making it difficult to make dollar debt repayments says this report in WSJ. The problem extends beyond drop in standard of living for average Turks. The country's banks are affected and companies that have borrowed heavily in US dollars and foreign currency denominated debt. A large mismatch between foreign currency debt such as dollar debt and the country's foreign exchange reserves has led to countries such as Argentina falling behind and seeking IMF assistance. WSJ points out that Turkey has about $160 billion in foreign exchange assets, and $280 billion in liabilities as of August 2021, according to the Turkish central bank. Bank lending in foreign currency is 24% to 45% of their total loans in the first half of 2021, according to Fitch Ratings. This could lead to dollar debt rollover difficulties as debt repayment comes due in April 2021. ...

LyrArc Article Gist
British regulators say they have"absolute confidence" in the Pfizer vaccine after analysis of over 1000 pages of data on the vaccine. The vaccine was approved by the Medicine and Health care products Regulatory Agency. The first vaccines to be shipped to Britain are being packed in Belgium. Britain has secured 40 million doses enough for 20 million people. Vaccination will begin as soon as doses reach Britain. The NHS will prioritize, first care home staff and residents, then healthcare workers, followed by people over 80 years age. Clinically vulnerable people will get a jab alongside people ages 70-74. People with severe obesity and underlying conditions will get jab after people over 60 years, followed by people over 50 years. About 34% of the 66 million population of Britain is over 50 years age, which is about 22 million. This means the Pfizer vaccine ( with doses already secured by Britain enough for 20 million people) covers over 90% of these people or 19 million people and the 1.1 million workers in NHS. Rapid progress in vaccinating these people would make Britain the first country in the world to have done this, a remarkable achievement. By the end of the year the Oxford vaccine should also be available making it possible to proceed with vaccinating the rest of the population of 46 million people. ...