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President Biden called for corporations to pay their fair share of taxes so that investments can be made in vital needs of the nation-US infrastructure, education and health, transport, public services. The NYT looks at companies where profits are shifted overseas to reduce taxes. In this case NYT looks into an investigation into shifting of profits to a Swiss subsidiary to avoid billions of dollars in income taxes. 

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With majorities in both houses of parliament Lopez Obrador now has the mandate to come up with an independent position for Mexico on issues of NAFTA negotiation, and social programs to lift Mexico's poor and working class, come up with a new way to reduce violence and corruption in society.  Stakes are large in the relationship with the U.S. Mexico exported $340 billion of products to the U.S. and imported $276 billion in goods. The team of Mr. Obrador sees the need to plan conversations with the U.S. carefully recognizing that Mr. Trump is not a lunatic, but a man with a political plan, says Marcelo Ebard, a top adviser to Obrador. On migrants even as Mexico has detained 76,000 central American migrants Lopez Obrador sees Mexico as a nation of refuge, and says migrants rights must be respected. On NAFTA Obrador supports the current negotiations and will have his advisers present at the negotiations. Obrador says Mexico is a country with a lot of natural resources and wealth, so that "the demise of the existing NAFTA will not be fatal for Mexicans." ...

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President Goodluck Jonathan as "Mr. Clean" aroused many of the same hopes now aroused by the election of Buhari as president of Nigeria. Under Goodluck Jonathan Nigeria's foreign reserves declined from $50 billion to $33 billion, and there is $1 billion in the sovereign wealth fund. About $20 billion in pilfering of state funds was reported by the Central Bank of Nigeria, but no action was taken by Jonathan. Indians may pride themselves on a better performance, yet prime minister Singh of India, seen as "Mr. Clean," allowed auctioning of telecom licenses in the second term, that had to be cancelled because of corruption. Throughout emerging markets not just in oil producing countries, poverty remains entrenched, because funds that should go into infrastructure and services are misused, which creates a disincentive for foreign investment, further adding to the problems in these countries. India and Nigeria are the two fastest growing countries in the planet, and the unspoken fear is that the demographic dividend with so many young people will be wasted by corrupt and inefficient management of the economy and resources of the two countries. The time lost in the last years of the Singh administration and the four years of the Jonathan administration will never be regained, the hopes of millions of young people are dashed again and again, and the goodwill of Europe and the U.S. eager to participate with the latest technologies in the development of the two countries, as they have done in China, is wasted....

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Scientists worry that microplastics are linked to growing rates of cancer, heart disease, and other diseases. One study says people inhale or ingest 74,000 to 124,000 microplastic particles per year through breathing, eating and drinking. The plastic particles are everywhere around us. Of 10,000 chemicals used in making plastic a fourth of these are toxic. Consider in 1950 2 million metric tons of plastic were made, now 400 million metric tons. Of 8 billion tons produced only 10% recycled so the rest are in oceans, landfills, and around us. Ingested or inhaled they cause inflammation in our bodies that lead to cancer or other diseases.

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Michael Barbaro describes how Romney reflected on his loss for the Republican nomination and worked hard to get things right in 2012. Romney does not see himself in the way voters did in 2008- as uncaring, emotionally detached, and somehow not authentic.

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Greg Ip of the WSj points out that Britain is in a weaker position to tackle Brexit than it was when Boris Johnson called for supporting the Yes vote to Leave the EU three years ago in the referendum. Business investment is lower than France, Germany and even Italy. And today protectionism, nationalism, hostility to globalization mean that its not so easy to increase exports by signing free trade agreements with other nations. Even a treaty with a friendly Trump administration  is not certain as Mr. Trump favors looking at how he can get the best deal and reverse any advantages of other trading nations, Britain being no exception. A trade agreement with the U.S. could mean the U.S. barring Britain from signing one with China as a condition of Mr. Trump. Greg Ip also points out that it was precisely joining the EU that helped Britain catch up with German and French standards of living after a period of low growth, inflation, and balance of payments crises in the 1970's. Joining the European Economic Community was as prime minister Heath stated would " enable us to be more efficient and more competitive in gaining more markets not only in Europe but in the rest of the world."   ...

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WSJ's Monica Langley provides an exceptional report with a close look at the first woman CEO at a large corporation in the cusp of great change. IBM CEO Ginni Rometty is remaking IBM by moving out of existing businesses and shifting to new growth areas such as analytics, cloud computing, new R&D advances. She sees her job as building the IBM of the future, and this includes divestments and phasing out of some businesses, acquisitions, and building some businesses such as the Watson Heath Care business from scratch. In some fast growing areas such as cloud computing this means competing with other established competitors, Amazon, Google, and Microsoft. Rometty's job is tough because of the size of IBM with 380,000 people in 170 countries, a culture that lacks the agilityof younger companies, and the older businesses which continue to slow IBM's progress, and where divestments reduce revenues. IBM sales are down for 12 consecutive quarters from the year earlier quarter. IBM's share price is down about 10% since Rometty became CEO in Jan. 2012, resulting in investor dissatisfaction with results. Rometty's goal is for 40% of IBM's revenues to come from corporate markets in analytics, cloud computing, cybersecurity, social networking, and mobile technologies, increasing it from 27% of about $93 billion in sales in 2014, and 15% of $105 billion in sales in 2013. Sold off and divested are low end servers, IBM's chip maker, and other hardware businesses. It is so extensive that whats left of the mainframe business is focussed on new technologies for mobile. Rometty setup a partnership with Apple for the corporate mobile market, and started Watson Health as a new venture in analytics for healthcare using its Watson Computer technology. Rometty grew up in Chicago, one of 3 daughters raised by a single mom, who says she was taught to be "fearless" by her mother. She graduated from Northwestern University with majors in electrical engineering and computer science, joining IBM as a systems engineer in 1981. She carries a backpack, school size notebooks, on her frequent trips to see customers in person and is constantly prodding employees at IBM to go faster. Rometty has a passion for scuba diving in her spare time and always carries the gear with her. Christine Lagarde at the IMF is one of the few women heading large organizations that have the same level of energy. Lagarde's passion is swimming having competed in sychronized swimming, and both Rometty and Lagarde describe the loss of a parent in different ways as a significant impact in their life. ...

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About 400 million or one in 4 people people smoke in China. State ownership of the tobacco industry only makes this worse. Enforcement of bans on smoking is lax. Experts warn that this would become a major healthcare problem in China.

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A law passed in 2009 provides legal enforcement for a 2002 amendment to the constitution of India that makes education a fundamental right for all children ages 6-14. It requires the government to see that there are schools for all children within 2 miles of their neighborhoods.

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Stephanie Nolan reports from Kenya on the spread of mosquito borne diseases such as dengue and malaria as new insecticide resistant mosquitoes pose a serious threat in African countries. Malaria can now be found in cities in Africa in the dry season, and during the pandemic the threat of malaria has grown significantly. Public health systems in African countries are straining to cope with this. It now poses a threat in the US and the EU.

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Blue Dog or corporate shills, who are they, asks Thomas Frank. He reminds readers that Illinois Senator Paul Douglas advised people in 1932 not to expect much from the Democratic party. Douglas said the Democratic party was more like alifeboat for business interests, when the going got tough with the Republicans, business interests simmply used this lifeboat to get away. So he says call these Blue Dogs caucus the Lifeboat caucus, and you get closer to the mark. He points out that the Blue Dogs are some of the leading fundraisers in Congress. See the link to Max Baucus in the Senate, who the NYT describes as a leading fundraiser from Montana.

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This editorial in the WSJ raises questions about Chief Justice Roberts' written majority opinion, and says Justice Scalia's comment about SCOTUScare should be replaced with the term RobertScare. It says Justice Roberts has emerged twice as a "political" Justice in the way he has interpreted the law in this case.

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Dr. Muller, Emeritus professor of physics at University of California, Berkeley, and Dr. Quay, founder of Atossa Therapeutics, point out why the presence of double CGG sequence  in the coronavirus genome is strong evidence of gene splicing done at the labs in research settings. The purpose of the research is to increase the lethal effect of existing virus and it goes under the harmless sounding term gain of function research when it is a risky and dangerous form of research. Other articles in the WSJ refer to the lifting of the ban on such research by NIH and HHS in 2018, in the face of fierce opposition from the scientific community at large, including the Cambridge community. Harvard's School of Public Health carried articles by epidemiologist Marc Lipsitch about the risks of "an accidental epidemic" which were ignored.

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Copies with slight changes to extend drug life with new brand names- Clarinex for Claritin, Nexium for Prilosec, Paliperidone for Risperdal being the latest in this new marketing strategy of drug companies to extend the life and sales of a successful drug. The drug companies try to market the copy drug as a significant improvement, which is what J&J is doing with Paliperidone. Experts are skeptical. Pricing of the generic versions of Risperdal or its copy will be much less expensive. Cost is a sensitive issue. About 15% of Risperdal's $1.35 billion sales were from Medicaid, generic substitutions offer potentially large savings. Meantime J&J did not do clinical tests between Risperdal and Paliperidone, the tests with 1600 patients compared Risperdal with a sugar pill. A psychiatry Professor at Duke and another professor at NYU are skeptical of J&J claims for Paliperidone. United Health shows savings of $150 million by using generics instead of Nexium, so managed care payors will tread carefully....

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The National Childhood Vaccine Injury Compensation Program protects vaccine makers from much of the litigation risk faced by pharmaceutical manufacturers. It limits compensation for death to $250,000. This special vaccines court is called Office of Special Masters at the U.S. Court of Federal Claims. This may be one reason for Pfizer's willingness to pay $68 billion for Wyeth which is amaker of childhood vaccines. Vaccines will generate $21.5 billion in sales by 2012, according to Sanofi-Aventis. Vaccines are biologic products that can't be copied. Wyeth's Prevnar is designed to protect children against 7 strains of pneumococcal disease. It has sales of $2.7 billion projected to grow to $5.5 billion in 2015 according to Sanford C. Bernstein & Co. Vaccines have driven huge reductions in childhood diseases, and the Act is designed to potect makers of vaccines, who suffered from excessive litigation in the 1980's.