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Hingh unemployment in important states including Florida, Pennsylvania, Colorado (8%). Unemployment has improved in Ohio (7%), Virginia and Iowa (6%).

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Chancellor Merkel meets President Trump in a key summit in March 2017. The two leaders have different styles, one flamboyant the other reserved. Chancellor Merkel tells the German media "it is better to talk with each other than about each other." Trump called Merkel's refugee policy "catastrophic," Merkel has said that the Geneva convention requires countries to do this on humanitarian grounds. On trade German's Economy minister Brigitte Zypries says Germany would file a suit on any hike in import duties at the World Trade Organization, that WTO rules restrict import taxes to 2.5% on autos. Germany's BMW plant in the U.S. exports more autos than GM and Ford put together, and Merkel is likely to emphasize large German investment in the U.S.. The heads of BMW and Siemens and other industry executives are accompanying Merkel to the U.S. as trade will be a key topic.

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Mervyn King, the governor of the Bank of England, is coming under increasing criticism for supporting the Conservative-Liberal coalition government's austerity plan, and for lack of efforts to fight inflationary pressures. On a major issue on which King has taken a clear stand- that the largest British banks should increase capital levels exceeding the international standards- not much has happened. Consumer prices in Britain were up at a 3.7% annual rate in December, and the government's austerity policies will also cause pain. In a recent speech King said that the Bank of England had limited ability to fight the higher unemployment and increased inflation. It was an admission of the limits of central bankers in the current situation. King said "a squeeze in living standards is the inevitable price to pay for the financial crisis and the subsequent rebalancing of the UK and world economies.

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Deborah Liljegren, a 49 year old accountant working for an advertising firm, was laid off during the coronavirus first wave. She now works as a warehouse worker in 12 hour shifts at a warehouse near Lake Geneva in Illinois. She gets up at 4.50 am for a 30 mile drive to the Kenosha, Wisconsin, located warehouse, a 1 million square feet Amazon warehouse facility. She is by herself most of the day in a 10 foot long area where she takes hundreds of items an hour from containers and puts them in tall shelves on a robotic run container production line. During the lunch break she eats a 30 minute lunch of a sandwich and cup of Cheetos inside her Focus car in the parking lot. This is the only time she gets to herself. At 12.00 pm she starts a new shift till 6 pm. At 2.45 she gets a 15 minute break.  Liljegren says it is a totally different experience going from a white collar to a blue collar job. On a typical day she may sort 2000 items. The pay is $15 an hour. She decided to take the job  because it looked like it would take a long time for another job to be available. Liljegren is one of the millions of workers whose lives have changed after the coronavirus. While a small section of society of professionals continue to work from home and do not feel the economic effects of the pandemic, much larger parts of the people of each country are vulnerable to the impact of the first and second waves of the coronavirus. With the second wave comes more economic uncertainty, loss of jobs as some businesses close, and others layoff employees.  Government budgets are strained in November 2020 to provide the kind of stimulus provided in March 2020, leaving businesses of all sizes vulnerable.   ...

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Juan Montes of the WSJ describes the problems facing states in Mexico as the governors have accumulated power, debt has risen rapidly, and accountability of state officials is at a new low. Half of the states with elections in 2016 have doubled their debt in 6 years, according to government data. The federal audit office points to irregularities in $13 billion of federal funds transferred to states. Elections in states in 2016 shows public discontent with poor governance, corruption, and the lack of rule of law. This is leading to a close election in Veracruz with the PAN and PRD parties challenging the PRI in the state.

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Russia's deputy prime minister Vladislav Surkov resigns in May 2013. Putin reprimanded Surkov for not implementing presidential orders and decrees. For about 13 years Surkov has guided policies for a tightly managed political system which he called "sovereign democracy." He was deputy chief of staff to Putin and Medvedev for the last decade, and headed the Kremlin Department of Domestic Politics. After street protests following the 2011 parliamentary elections, Surkov had second thoughts about this, and called the protestors "our best people." He was transferred to his current job as deputy prime minister at that time, and sidelined by Putin in Dec. 2011.

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An index for consumer prices for the U.S. was up only 0.8% for the 12 months of 2014, according to the Bureau of Labor Statistics. This is well below the U.S. central bank's target of 2% inflation. It creates uncertainty about whether the U.S. Fed will raise interest rates in 2015.

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Novartis is taking a new approach to drug research and drug discovery. The old one which was popular in the drug industry was to go directly for blockbuster drugs for large numbers of users, with a long time in the research pipeline because the area of research was largely an unknown. This was costly and becoming less and less productive. Dan Vasella who heads Novartis, is taking a different approach which comes from his understanding of medical science as a physician, in an industry run by accountants, lawyers and business people. This is to go after wellknown molecular pathways identified by Dr Fishman at Harvard in his research, and do this by taking on problems in diseases that afflict small numbers of people. These drugs have some established medical science to work with, and the research work takes a shorter period. Once the drug proves its effectiveness in one illness, it is tested for other illnesses that afflict a large number of people but which shares some of the same underlying phenomena that cause the disease in the two situations. Dr Vasella stumbled on this approach after the development of the drug Gleevec by Novartis. Gleevec was originally approved for a rare blood cancer, but has now shown to be effective against six other dieases. Gleevec brought 3.7 billion in revenues in 2008 for Novartis. In 2002 Vasella made a bold move to discard the old drug development model. The basis of this approach was to go after new drugs that were desperately needed and where the genetics of the illness were well understood. Whereas pursuing rare dieases is considered foolhardy by most drug company leaders, Vasella's idea is to use the common genetic underlying arrangements for that drug to go after other diseases that would be good prospects for the now proven drug. The known genetics makes it possible to complete the research in a shorter time. In 2009 Novartis has 93 drug candidates in the pipeline, 40% more than 3 years ago and 80% of Novartis' drugs last year made it from early testing to late stage development. This was a 60% improvement over 2005. The new approach fits the current regulatory climate, with regulators concerned more about safety, and Medicare and Medicaid and other payor less willing to pay for treatment with modest benefits or with uncertain outcomes. The approach had to be executed in terms of organization and staffing. Vasella moved the R&D global research operation from Basel to Cambridge, Massachusetts, and spent $4 billion on the move. He recruited a renowed researcher and cardiologist at Harvard University, Dr Mark Fishman, who had done research on the genetic mutations in the cardiovascular systems, to run the center and set the new direction for global research. Fishman convinced Vasella that medical research should focus on a small number of molecular pathways- the complex suquences of interactions among chemicals, proteins, and larger cell structures in the body that are behind all illnesses. Says Fishman, there are 24,000 genes in the genome, but only a few dozen pathways conserved through evolution. Fishman's theory is that you find all the links in a pathway and then locate the signals that can turn the genes on or off to develop medicines for illnesses. Bercause disease after disease share a common pathway, the knowledge gathered can then be applied across that region with more accuracy and directly, to address a range of illnesses. Fishman's approach means marketing and sales no longer make the decisions. There is a new method for doing things. Fishman focusses on clinical data and insists that commercial analysis comes after sufficient clinical data. A major restructuring in 2007 led to shedding 1260 sales and marketing jobs, as clinical science now takes precedence and medically trained scientists take senior leadership positions. The new approach is being used for a drug developed for Muckle-Wells syndrome. Computer simulations are shortening the time to late stage trials. The drug has applications for Type 2 diabetes and severe arthritis. The whole process will take many years, as its a sea change for the industry and for Novartis, a fresh approach when the approach used by the pharmaceutical industry for so long is failing. An oral drug treatment for multiple sclerosis is being developed along these lines. Afinitor. approved by the FDA for kidney cancer in March shows potential in six other diseases, including lymphoma where Afintor shrank tumors by 50% in one third of the patients in a trial. ...

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Eric Holder Jr, the Attorney General of USA, told the Financial Crisis Inquiry Commisssion that the F.B.I. was investigating more than 2800 mortgage fraud cases. Of these 2800 cases, 1842 are classified as major cases, involving losses of more than $1 million. In addition federal charges are pending against 826 defendents. Lanny Breuer, assistant attorney general of the Justice Department's criminal division stated that the fraud cases included loan origination schemes, property flipping, foreclosure rescue schemes and loan modifications. Those accused of wrongdoing include real estate brokers, appraisers and bank insiders and "plain old fraudsters who gravitated to mortgage fraud." Sheila Bair in her opening remarks to the Financial Inquiry Commission, led by California state Treasurer Angelides, stated that it was necessary to find a way to breakup large banks without using the option of government support. Bair pointed out that the basic assumptions about financial supervision, credit availability and market discipline that were considered acceptable in the regulatory reform scheme for decades are now appearing seriously flawed. A whole reassessment was needed to change the existing mechanisms and methods. And she emphasized the serious distortions and imbalances in our national policies which moved away from savings to consumption, away from investment in our industrial base and public infrastructure toward housing, and away from real sectors of the economy towards the financial sector. Ms. Schapiro who heads the S.E.C. called for a stable , adequate funding to support the commission's work....

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Germany generated 45% of its energy from coal and 25% from renewable energy sources in 2013, according to AG Energiebilanzen. Chancellor Merkel, who as environment minister supported the Kyoto agreement in 1997, announced a plan to cut carbon dioxide emissions by an additional 62 to 78 million tons by 2020. The cuts will rest largely on improving energy efficiency, and with a third of the cuts in the power industry. With the drive to close 17 nuclear plants in Germany, the power industry has increasingly relied on coal generated energy. This is an effort to change this situation. It is supported by German public opinion.

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The 2011 State of the Union address by President Obama. A calculated effort to move the debates that will frame the future election to a different place. He emphasizes the importance of investing in the future, in global competitiveness, through spending on education, infrastructure, alternative energy and other projects. But there was little in the way of specifics for reducing the high jobless rate which stands at 9.4%. And little in the way of specifics of how the investments in the future for global competitiveness and infrastructure spending are to be achieved. Especially when the fiscal imbalances are growing after the compromise on the Bush tax cuts and the passage of health care legislation. The Washington Post says that a majority of Americans approve of his overall performance, yet they are generally negative in their evaluation of how the Obama administration and President Obama has handled key issues relating to the economy. And this is more so among independent voters who will be crucial in the 2012 elections....

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Richard Thaler, a Professor of Economics at the Booth School of Business, University of Chicago, on the reasons why millions of homeowners under water- owing more on their homes than their homes are worth- have not defaulted in large numbers. In places like Nevada nearly two thirds of homeowners are under water. Changing a home, changing school for children, losing one's credit rating, social stigma. He points out that the costs are outweighed by the benefits of getting out of an underwater mortgage, and research has shown this is contagious once the process of defaulting has started. So once the neighbors are defaulting its much easier to do so and the proces picks up momentum, the psychic costs simply decline. So he says the result is that we may face a tsumani of strategic defaults. Professors Posner and Zingales of the University of Chicago have a proposal. Banks should be required to provide loan modifications in neighborhoods with home prices having dropped over 20%. Banks would reduce the payment by the average price reduction in the area and get in return 50% of the average gain in prices when the house is eventually sold. This requires Congress to pass legislation....

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The National Association of Realtors reports that sales of previously owned homes dropped by 27.2% from June, to seasonally adjusted annual rate of 3.83 million homes. House prices gained ameasure of stability in 2009, after dropping since 2006. Now that measure of stability may be lost as house prices weaken. The expiry of a home-buyer tax credit was expected to dampen sales but not by this much. Paul Dales of Capital Economics expects a further drop of 5% in house prices. Combine this with sluggish consumer spending and prospects of deflation in 2011, a weak Obama administration HAMP homeowner relief program, fading stimulus and the likelihood of no further stimulus because of deficit fears; and the picture shows serious problems. The underlying picture of housing is not changing. One in four homeowners with mortgages owe more than their house is worth. Banks are handling over 5 million loans that are delinquent, if these loans are modified or short sales are permitted by banks, there would be support for housing prices. HAMP has failed in this regard, see the link to this....

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Vernon Jordan points out the problems with media and new tech and the loss of quality journalism. He says this has damaged the political process in the U.S. and Europe by spreading rumor as facts, and not providing reliable information, with news and entertainment not being separated. The failure to educate people he says, risks in Jefferson's words the "perversion of power into tyranny."

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The art of storytelling is important to startup companies and to job candidates in any field. What makes you interesting or different and worth the commitment as a startup or job candidate is the silent question that is posed in encounters with the public or the interviewer. Alina Tugend touches on the personal narrative we all need to get right for advancement. The Freytag pyramid provides a structure for the storytelling- with the first part the scene, second the rising action, third the turning point, fourth the denouement or closing which gives the listener some sort of release. For it to be effective our narrative has to be about our unique experiences with detail, it has to be genuine, it does not have to be perfect, just make that connection and gain empathy, trust of the listener, hopefully a new fan. For it to be real it becomes important to not self-censor. Other people may have the same experience but it is not talked about much, that itself may add to its newness and claim to being something fresh, and it may take some courage overcoming fear of ridicule to tell the story. Telling stories also can work to bring an organization or different departments work better around shared perceptions, values and goals. In this sense stories and narrative are about everyday life and anywhere we are trying to achieve something worthwhile. ...

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Prime minister Modi of India's visit to Japan in September 2014 leads to a commitment of about $35 billion in Japanese investment over 5 years. Japanese companies such as Suzuki, Toyota and Toshiba already have large investments in India.