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Glaxo made a calculated bet on vaccines in 2004 with the spread of the bird flu H5N1 virus in Asia. THis flu killed half of the people infected. At the time Glaxo was told by the Department of Health and Human Services for its Relenza flu vaccine-"how much can you make and how fast?" It reflected the high level of concern among the public, and the need for governments to respond quickly or be seen negatively by the public. Chief Executive Jean-Pierrre Garnier tapped David Stout to put togethe a team to focus on pandemic flu. New production lines were opened for Relenza in Australia, France and the USA. By 2005 governments in the USA and other countries were placing large orders for Relenza.

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The breakup fee of $4 billion and the $1 billion in "book value" of spectrum AT&T is giving to T-Mobile as part of the fee are part of the cost of the failed acquisition of T-Mobile. Other costs are that this puts AT&T at a significant disadvantage in relation to competitor Verizon, because Verizon is at least one year ahead in bringing out its next generation LTE network. By the end of 2011 Verizon's LTE network will reach 200 million Americans compared to AT&T LTE coverage of 70 million. Apple's next iPhone in 2012 will be an LTE model. AT&T's network congestion will mean it will have to do more capital spending than Verizon in the years ahead. Verizon has early mover advantages from its early investments in LTE network. From 2008 through the first 3 quarters of 2011, Verizon invested $29.3 billion in its wireless network compared to AT&T's $28.1 billion.

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Debbie Wasserman Schultz's vigorous efforts to fire up the Democratic party's base after the waning of support since the 2008 presidential election. She says it is a make or break moment for the middle class and drawing attention to the problems of the middle class is not class warfare. She was chosen by Obama as the Democratic National Committee chairwoman as the party heads into the 2012 presidential election.

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Republican governors hold governorships in 30 states in the U.S. They have a different perspective on the expansion of Medicaid envisaged in the healthcare law, as long term funding for the expansion is uncertain. With the deficit reduction planned in negotiations between president Obama and the Republican controlled House the outlook for money going to state funding is precarious.

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New film by Fabio Barreto on the life of Luiz Inacio Lula Da Silva, President of Brazil. Lula Da Silva has a 70% popularity rating in Brazil and the Barretos, a Rio based filmaking family, are strong supporters of the President. It shows the difficult childhood of Da Silva growing up in a one room house in a rural area of Brazil, his rise as head of the steel workers union, an automobile factory worker who becomes President on his fourth try. Lula himself says he started to cry at a screening of the movie when he saw the image of his mother. Says Barreto: the vast majority of poor Brazilians are portrayed as inferior and lazy, and less than what they are, and no one has has told these Brazilians that their people are strong.

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The competing choices offered between the Romney-Ryan ticket and the Obama-Biden ticket in the 2012 U.S. presidential election on how large the government should be. Romney-Ryan would keep U.S. government spending to around 19-20% of GDP, closer to its historical average, compared to around 22-23% for the Obama-Biden Democratic approach. The difference is in the approach with Republicans counting on reduced uncertainty for private sector investment to grow and generate jobs.

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India has 2.3 million of the 9 million tuberculosis (TB) cases reported annually. About 100,000 of these are drug resistant strains. Existing treatment methods do not work for drug resistant cases, actually exacerbating the conditions as the strains thrive if the antibiotics fail. Cases of drug resistant TB are reported in Mumbai, Bangalore and New Delhi. Experts say the $236 million India spends on TB treatment and control is not enough to deal with the problem. India lacks the machines that can detect drug resistant TB in 2 hours and patients with drug resistant TB wait for months taking treatments that fail before it is detected. The WHO provides these machines at a cost of $70,000 per machine and each patient test is $16. The first cases were detected in 2006, and India began building labs for this strain in 2008. So far 37 labs have been built treating 5000 patients. The WHO has tried to persuade India to get the diagnostic machines since 2010, which can do the work of detection for drug resistant strains much faster. These machines are in pilot programs and India will buy more if they work says Dr Kumar, head of India's TB program. Doctors at Hinduja Hospital in Bombay, including Dr. Udwadia, are not convinced and see the efforts as slow and bureaucratic. Dr Kumar says the government has focussed on regular TB which only costs $9 or 500 rupees to treat and cure compared to the $1800 or 100,000 rupees it takes to treat drug resistant TB....

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Chinese car company Shuanghuan's CEO was on display at the Franfurt auto show. Its rear looks like a BMW X5 and BMW has charged that it copied the X5 and filed suit to prevent it from being marketed in Germany. Shuanghuan also has a minicar that is called Noble which looks like the Daimler's Smart minicar. Daimler also is taking legal action to prevent the marketing of the Noble in Germany. Only the X5 was shown at the Frankfurt Auto show getting criticism from Reithofer who is head of BMW. Critics say that the Chinese actually have borrowed from several car designs and from different aspects such as the interior aand exterior of different brands,thus the X5 is seen as borrowing from the front of a Toyota Land Cruiser and the rear of a BMW X5. The price difference is huge 29,000 euros for the CEO vs 59,000 euros for a X5. Currently the Chinese are struggling with safety issues in their cars by makers such as Brilliance and the Landwind. Both cars did badly in tests conducted by the German automobile club ADAC. Landwind's model is being retooled for safety while the Brilliance which has a collaboration with BMW for the Chinese market presented a new subcompact the BS2 as an alternative to the VW Golf....

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Analysts say that if Greek banks pass the European banks stress tests to be announced this week, the stress tests must not be rigorous enough.

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Former president Lula da Silva of Brazil is sentenced to 10 years in prison on corruption charges. The charges are that Mr da Silva and his wife were illegally given about $1.1 million in improvements from a construction company for a beachfront apartment. The construction company was able to get lucrative contracts from the state oil company Petrobras. Many of Brazil's politicians are under investigation. The former speaker of the Brazil parliament, Eduardo Cunha, was sentenced to 15 years in jail for money laundering and corruption. The current president Mr. Temer is also under investigation. A culture where such activity was accepted had developed, and this effort started with a small investigation called "Operation Car Wash" in a smaller Brazilian city named Curitiba. Young lawyers determined to set a higher standard and fight Brazil corruption pursued the case that led upto the higher echelons of Brazilian government, the construction industry, and the state oil company Petrobras. ...

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Ford's CFO Lewis Booth says Ford will take a charge to its first quarter 2011 earnings and use cash or shares to cut its debt by $3 billion. This would lower Ford's debt to $16.1 billion. It would reduce Ford's interest rate expense by $190 million. Ford spent $1.8 billion on interest expense in 2010. S&P rates Ford at BB- or three levels below investment grade. S&P will not change its rating because it considers this part of Ford's ongoing effort to reduce debt.

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A van drove right into a crowd in the Las Ramblas promenade in Barcelona, killing 13 people. The terrorist attack was similar to attacks in London and Nice.

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Spain's Finance Minister Luis de Guindos talks with reporters House and Perez from the Journal in March 2012. He says the situation Spain faces is very serious and the risks of declining growth are high. He points out that either way Spain loses, if the spending cuts and higher taxes lead to further decline in growth, markets are likely to penalize Spain with higher interest rates on its debt; and if Spain is seen as not doing enough to reduce its deficit, markets will penalize Spain. The yield on Spain's 10 year bond increased to 5.3% on April 2, 2012. The 2012 budget presented by Luis de Guindos calls for 27 billion euros ($36 billion) in cuts to reduce the deficit to 5.3% from 8.5% in 2011. Spain's situation is precarious because the cuts come when unemployment is at 20%, and youth unemployment exceeds 50%. A general strike in March 2012 over labor reforms brought protests drawing over 800,000 people. The government's forecast is for the Spanish economy to contract 1.7% in 2012. Luis de Guindos says half of the 2012 budget provisions have been implemented, with 15 billion euros of cuts implemented in December 2011, and new taxes presented in the 2012 budget implemented immediately. To help local governments with poor finances and owing suppliers 30 billion euros, the Spanish government has set up credit lines as a stimulus move. The net impact of the budget actions, stimulus move, and declining economic growth will be to increase Spain's debt to GDP ratio from 68.5% in 2011 to 78.5% in 2012, according to Luis de Guindos. Spain's plan is for gross issuance of government bonds of $86 billion in 2012....

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The Supreme Court in a 6-3 decision, says Aereo, a startup video streaming service, violated copyright laws by taking broadcast signals on miniature antennas and giving them to subscribers for a small fee.

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Alexandria Ocasio-Ortiz a 28 year old campaigner for Bernie Sanders defeats veteran politician Joseph Crowley in a Democratic primary with 57% of the vote. It brings a wind of change to New York politics and to the country.