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The planned resubmission to the FDA for approval of diabetes drug Tresiba by Novo Nordisk with improved prospects. The Novo team has discussed its findings with regulators. If the resubmission is accepted Tresiba will be ready for launch in 2015 or early 2016. A once weeekly successor to Victoza, injectable treatment for diabetes, and an oral formulation for diabetes, are other new diabetes drugs Novo Nordisk plans to bring out. The oral formulation market is estimated at $13 billion by Citigroup.

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Polly Lower quit her job to take care of her granddaughter, and Eddie Gonzalez-Novoa quit a $88,000 job to help a nephew who is a cancer survivor setup his startup video-gaming and social media site, and provide childcare for his granddaughter. They are 2 examples of the equivalent of 2.5 million workimg people the Congressional Budget Office estimates will reduce hours or quit jobs and take the government subsidies to lower income earners for healthcare insurance in the U.S.

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President Obama comments on the Trayvon Martin shooting saying- "Trayvon Martin could have been me 35 years ago." Trayvon is a black youth shot by police in a Florida gated community. Obama was critical of racial profiling and gun laws. Obama said three sets of experiences are shared by African American youth- being followed in department stores, hearing the click of car doors locking as they cross the street, or watching women clutch their purses nervously when they enter an elevator.

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A businessman from Atlanta lands at his sister's small walk-up apartment in New York City in Jan. 2000. From there he makes cold calls to people on Wall Street to get support for his struggling business. Mr Sprecher does the unexpected over the following years as he gains backing and turns the InterContinental Exchange into a powerhouse in global computer trading. Sprecher's brings an unassuming and self-deprecating manner to the job of running the New York Stock Exchange from Atlanta.

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President Obama tells Hispanic high school students he supports a bipartisan plan for immigration reform from Senators Graham, McCain, Rubio, and Schumer. A critical part of the plan and the President's plan is a pathway to citizenship for 11 million illegal immigrants. Obama wants to see a pathway "from the outset," senators say this should happen after stricter enforcement requirements are met. If the senators do not move ahead with this plan the White House will put forward his own plan.

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A research paper by the Federal Reserve Bank of New York shows 43% of Americans in 2012 under the age of 25 with student debt, having average debt of $20,326. Compare this with about 25% of young Americans having student debt in 2003, with average debt of $10,649. This is crowding out other borrowing such as buying new homes or cars by younger Americans because of borrower unwillingness to take on more debt and banks unwilling to lend to borrowers who might default.

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In an historic event, the young Senator who introduced bills on improving fuel efficiency in the Senate only a few years ago, announces his proposal for a single national fuel efficiency standard of 35.5 miles per gallon in 2016. Mr Obama had the chief executives of 10 global auto companies all gathered together, as he made the announcement. It reverses decades of conflict on this issue, and puts the US at the forefront of developing new technologies for fuel efficiency and emissions control.

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Bubb and Kaufman say that a study they did on credit union and bank credit cards shows that credit unions offer better terms to their credit card holders than banks. And it is possible for banks to offer these better terms. Most Credit union cards they say do not increase the interest rate if the borrower fails to make aminimum payment on time. Ans credit union fees for going over the credit limit are on average just half of those of bank issuers.

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Charles Blow says blacks are suffering higher foreclosures, higher unemployment, and the quality of life for black people is collapsing, as President Obama is not listening or paying atttention to the pressing needs of black people. His point is that Obama needs white voters more than he needs black voters. He sees Obama more as a gamesman now than agamechanger for black people. And he talks about a backlash amng black people, as black people are getting disenchanted with Obama.

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According to Goldman Sachs David Kostin the S&P at 500 is quite possible, and its not abig stretch. At earnings per share estimate of $40 to $50 a share and a P/E ratio of 10 which are realistic in this climate, you get the S&P in the 500 range. the notion of the Dow at 5000 and the S&P 500 at 500 are not unrealistic especially if the stimulus is not adequate or not as effective.

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Julie Cohen, Georgetown University Law Center, on fair use doctrine of copyright law and the standard for how consumers can use copyrighted content, especially for criticism and commentary. How does this relate to the analysis and commentary of Intelilinks? She said fair use could involve for example, compiling and analyzing copyrighted visual images to create a visual search engine, transferring a song from a CD to an MP3 player or compiling film clips to create a multimedia presentation for a school assignment.

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Makin's view the Fed print money to purchase mortgages directly or purchase Treasury securities directly. Monetary easing has not ocurred and Makin thinks this risks a severe recession. The 15% of homeowners with negative equity and the 20% with marginal equity have little access to credit, a serious foreclosure crisis is looming. Feldstein bernanke and now Makin all lend their voices for serious action to help homowners from going into negative equity where its rational just to walk away from their homes.

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Names like Michel Flournoy, Susan Rice, James Steinberg, at the think tank Center for a New American Security, a think tank setup by Flournoy and Kurt Campbell a former Clinton National Security Council and Pentagon official. Its positions itself between Republican and Democratic positions for some kind of middle ground. Will it bring the new or fresh thinking and imaginative ideas as Obama has raised hopes for, if all it does is takes the old Clinton officials positions and refashions them.

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Theories circulating about the Panama Papers, including one about Putin from a Brookings Institution expert that it was designed to embarrass western leaders such as Mr. Cameron. Questions about that theory would relate to why this would bring up connections to China's ruling elite.

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Losses at China's 3 largest airlines Air China, China Eastern, and China Southern will reach 20 billion yuan or $2.9 billion for 2008. Large capital injections and suspension of atax on jet fuel surcharges is the form of government help for these state owned airlines.

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This countercyclical regulation advocated by Charles Goodhart and others including some central bankershas been discussed a lot at USA Federal Reserve Bank conferences. But though some central banks have tried to do this it has not ocurred in the US, UK and most European countries.

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Janny Scott's account of the life of Stanley Ann Dunham, President Obama's mother. This gives a glimpse of the period when she lived in Indonesia, where she spent most of her adult life. It describes life in Indonesia at the time for the expatriate American community in Jakarta. It also shows how she believed in her son, how she made great effort to give him the opportunites he needed for the best education, and the formative experiences in Obama's early life.

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The ratification of the European Union's Fiscal Treaty of Dec. 2011 will require a two thirds majority in both houses of parliament. The coalition government of Angela Merkel lacks such a majority. This means the support of the Social Democrats and the Greens party will be needed to pass the treaty in Germany. The Social Democrats parliamentary leader Frank-Walter Steinmeier, says he cannot "picture an approval of the pact without growth-boosting measures." The Merkel position of strict austerity policies in tackling the eurozone debt crisis has come under intense criticism for lack of growth boosting measures. Recent economic performance clearly in Greece and Portugal, and to some extent in Ireland, Spain and Italy, shows the decline in GDP with austerity cuts alone will worsen the deficits or lead to a prolonged period of economic stagnation.

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Note that Goldman Sach's analysts who first predicted that oil prices could reach $100 are now predicting that the downward momentum is building up. The prediction from them now is that prices may go up further than the $96 right now but should drop to $80 by April. Its not too difficult to see why. First on the supply side the momentum for downward shift is not so significant but still there are signs. The Iraqi oil flow disruption either from a Turkish invasion of norther Iraq or from internal disruption is shrinking as the Turks see this as a small operation at most, and the Iraqi law and order situation is improving. The Iranian situation may be stabilizing without US intervention possibilities shrinking. On the supply side the oil majors except for Total see their output shrinking somewhat, and OPEC has not increased supplies significantly as oil inventories have not built up as they do before winter. But overall the supply situation is stable. On the demand side is where the significant downward momentum exists. With the US economy slowing down amid the buildup of the housing tumble and the credit crunch which looks to get worse in 2008 before stabilizing in 2009 and a stronger euro and other factors affecting Europe's expansion oil consumption by industry in the industrialized countries is slowing. Much of the pressure on oil prices comes from increases in demand each year from China and India. Here gasoline is subsidized by the government and this reduces incenive for conservation. The policy of letting market prices be reflected at the pump to a limited degree so as not to seriously affect people is now taking hold in these countries. In China prices were raised 10% and there is likely to be further increase in the near future. This along with the increasing awarenes of the dependence on foreign oil and the need for conservation in both China and India should build pressures in both countries to make the best use of resoures and have users share some of the burden of higher prices. The American and European gasoline market is driven by a public that has not been too conscious of conservation especially in America. It appears that high oil prices have not encouraged conservation, witness that with rebates for higher oil prices and zero interest rates financing large pickups are still selling at levels of 2005, and there has not been a significant reduction in consumption at the pump. What may shift this equation now is probably government mandated fuel economy standards. Europe already has new standards and the automakers there are racing to meet it with new technologies, in America its now almost certain that public sentiment and congressional sentiment is likely to lead to similiar standards or at least significantly improved standard. Public sentiment is already pushing the automakers in the USA to introduce new models with higher fuel economy and use this as a n advertising and competitive edge. This reduction in gasoline consumption at the pump through new technologies in the industrialized countries and through price increases being allowed to flow through in the developing countries of China and India in a stable supply environment where the downward political risks are stable may be the pivotal turning point for the price of oil. ...

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How ethanol picture as a useful alternative fuel has changed completely in the past year. The economics of ethanol also have changed completedly in the past year, as corn prices have risen to above $3 abushel and stayed there, even with the biggest corn crop since 1945, and prices of ethanol have dropped with huge oversupply of ethanol from $5 a gallon in June 2006 to about $1.85 a gallon today. Global ethanol production has grown from 10.9 billion gallons in 2006 to 13.4 billion gallons in 2007 according to IEA. US's ethanol production is about half of this or 7 billion gallons and is up 80% in 2 years. The production capacity of ethanol with new plants is expected to jump to about 12 billion gallons in 2008 even as demand for ethanol is about 7 billion gallons.This huge oversupply accounts for the drop in prices of ethanol with margins dropping from $2.30 in 2006 to 25 cents in late 2007. Its become less and less attractive as an alternative fuel as more studies appear and more groups cite the different ways in which ethanol has destructive effects on the environment. Corn is in demand by food companies and by livestock companies in the USA and generally across the developing world so raising corn prices is seen very unfavorably around the world. Nation Academy of Sciences study and a National Research Council study says corn based ethanol could strain water supplies and impair water quality. American Lung Assocation worries about the the air pollution from burning ethanol in gasoline. And a EPA Spring 2007 report says ozone levels increase with increased use of ethanol. A study coauthored by Nobel prize winning chemist Paul Crutzen says it might exacerbate climate change because of the added fertilizer used to produce corn raised emissions of nitrous oxide. All this has made people wary of ethanol and much of the early enthusiasm for ethanol has vanished. The lobbying struggle pits the ethanol producers and the farm lobby in the midwest against oil companies which don't like being forced to use a non-petroleum fuel even with a subsidy of 54 cents of gallon for blending ethanol into gasoline, and food and livestock companies which need corn at lower prices. Add to this the weight of environmental organizations and countries across the developing world which simply don't like the idea of using scarce food resources in this manner and find this to be just not a right thing to do for the world's poor which need corn as a basic food source. Consider Mexico where this affects the price of a staple food corn tortillas and China which bans the use of corn for making biofuels, both countries seek to keep food prices low for the country's large numbers of rural and urban poor people and could see the stability of these countries disturbed by huge rise in food or fuel prices. As a result of all this the ethanol lobby is looking to Congress to mandate a certain usage figure of ethanol in gasoline production in the new energy law. This legislation now could become controversial in the future as better ways of solving the energy crisis such as automobile fuel efficiency reducing demand and conservation, as well as other alternative sources that have fewer adverse environmental impact come into play. ...

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The president of the U.S. Chamber of Commerce China Center says the White House has a supportive community when it comes to getting China to abide by fair rules relating to intellectual property. Mr. Bolton talking to the CEO Council was frank about the U.S. government's efforts to get China to to implement a broad set of reforms. He even called for a show of hands from executives who think its acceptable to live by the situation today which hurts the U.S. when it comes to intellectual property. No one showed their hand. U.S. executives once skeptical about the tariffs from president Trump on Chinese products are now shifting their views on the confrontational approach taken by president Trump on issues of U.S. technology transferred to companies in China that lead to the U.S. losing its technological advantage.

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Accounting rules that require companies to value the securities they hold at the prevailing price in the markets even if the prices swing sharply. On a day the Dow dropped 315 points the 11.3 billion dollar writedown taken by AIG was part of the reason for loss in confidence. This loss was based on taking the prevailing prices and taking the writedowns. If this were to be adopted widely it would in the long run give more confidence to the markets and avoid the Japanese scenario where losses were not correctly reflected prolonging the downturn, but it would mean a bigger initial shock to the economy as losses would be higher. Ben Bernanke doesn't have the answer or even an idea what would to do aboiut it and leaves it to the best judgement of the accountants.

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America has its own conversation points. Ischinger says we would love to vote in the US election as it affects us greatly. Americans would love to vote in the German and French elections as it affects us. As America fights to give workers and families their rights and invests trillions of dollars in infrastructure when will Germany and France do this? When will Germany and France fight to give all workers and families opportunity to get ahead and make a decent living? Are Germany and France aware that the Biden-Harris, Biden-Walz fight is for domestic policy to determine foreign policy and this is the domestic policy of America. Wolfgang Ischinger ,who heads the Munich Security Conference Foundation, writes in NYT about the importance of keeping the conversation with European allies going. He says US and European Union do not have a common policy towards China and this needs to be discussed and clarified. US and EU need to come closer for NATO to carry out it's mission now that the EU countries are shouldering a fair share of the defense burden in percentage of GDP devoted to defense. Ischinger says the Europeans are not investing defense dollars efficiently and developing European arms suppliers. His third point is that there should be consistent application of rule of law, democracy and western values in policy to build the alliance. He remains blissfully unaware that the same divisions that are fostered in America exist in Europe and some of them started in Europe- for Europe to be strong it must invest in its People, in workers and families and in infrastructure, domestic policy will become foreign policy.    ...