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WSJ's Christopher Mims shows the failure of tech startups in low margin industries in which the startups added little real innovation. What he does not say is that these so called "tech startups" have caused a massive capital misallocation and poor productivity of capital for trillions of dollars of American savings. This  happened when the productivity of capital for infrastructure and manufacturing industries in which the US has fallen behind is increasing. It has also caused "crowding out" of essential government investments in infrastructure and manufacturing in the US. In food delivery, used car delivery, online streaming and a whole range of business startups sales are falling as consumers hit by high inflation are budgeting carefully for all expenses. Many are disappearing after years of losses leaving a trail of destruction that includes the unrealized infrastructure and manufacturing that America's communities so badly need.  ...

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Dr Kevin Lee, a British neuroscientist, heads EpiNova, a 60 person unit within Glaxo's R&D department. Lee founded two biotech startups before joining Glaxo. The smaller units called Discovery Performance Units are Glaxo's way of creating biotech startup like units which it is hoped will produce better results. The 36 DPU's in Glaxo R&D are given 3 year budgets and flexibility to make their own decisions for drug research. The large bureaucracy, scientists not working across fields and an older mindset are seen as obstacles in the search for new drugs. EpiNova with its own logo operates in a a Glaxo facility, an hour north of London. Decisions are made faster, says EpiNova chemist Dr. Wilson, and the atmosphere is that of a startup willing to try new approaches quickly.

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Being able to set your own targets and goals is important for a startup. Doing something you love is important because you will be doing this a lot of the time. Making sure one keeps activities outside of work is important to be able to maintain balance and vitality.

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Lessons for startup Jive, social networking software for business financed by Sequoia Capital. It did well in the beginning with a number of high profile sales. Then things fell apart with inexperience and a series of mistakes. With $15 million of capital raised from Sequoia in August 2007 discipline started to fall away, bad hires were made in a hurry to speed things up, staff tripled to 150 by the beginning of 2008, and there were a lot of problems with the new software. In October Sequoia went in and fired 25, 3 managers, and cancelled a project. Sequoia Capital held a direct talk in October with executives of its 100 companies, and about 1000 layoffs were made. The presentation was direct, showing a pig with a butchers knife in its head and the slide reading R.I.P. Good Times, saying that for startups it would be the survival of the quickest, the companies quickest to cut costs and be profitable. The sales people just took on as customers anyone who was interested or called. And as the economy worsened and this software was not an essential purchase they cancelled. Now the new sales approach is to say no, and get customers who actually save money from using the product or see some vitally important benefit. The sales person actually tries to find out about a company's plans, its budgets, to see if there is a good fit. Jives at this point is a survivor....

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By offering the prospect of higher returns in a low return environment venture capital firms are raising new funds at the highest rate in 15 years in 2016. Venture Capital firms have raised about $13 billion in the first quarter of 2016 from pension funds, endowment funds, and other sources, with about 50% of the funds going to about 7% of the total number of firms, according to Venture Source- including $2 billion to Accel Partners, other firms are Andreeson, Founders Fund, Kleiner Perkins. The returns for ten years from venture capital are about 11% compared to 6.8% for S&P 500 index, according to Cambridge Associates. Usually the fund capital raising lags behind market downturns. Much of the returns for some of the startups are not reflected in cash inflows with returns being large on paper, and startup financing has increased for firms, resulting in capital shortages and more fund raising in the industry.

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Issues relaed to tech startups driving up rents in residential neighborhoods of San Francisco, London, Berlin, Stockholm, and other cities.

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Nahm says the most important quality for a person doing a startup is passion. With this should come a clarity of vision which helps him or her focus on one thing that can create something that stands out, without getting diverted in many directions. He also believes a questioning and observant mindset is important, as a person doing a startup has to respond to what is happening outside by searching without having any preconceived ideas.

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Large drug companies are raising money in the bond markets to finance their mergers and acquisitions. Will this result in better research and new products/ At the same time as this is happening the capital markets are doing little for biotech startups and biotech startup are running short of cash, most of them having 6 months of cash to support them. See the link to this.

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The popularity of networking services such as Angel List, which matches startups with investors, has made financing more accessible. Other developments that assist startups is the increase in capital that is being invested, the new category of "F" shares, and the interest by investors in letting founders run the company to achieve their vision.

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Quentin Hardy gives this exceptional account of a startup company named Box in cloud computing services, based in Los Altos, California. Co-founder and CEO, Aaron Levie, faces a cash burn rate and larger competitors, as Box had losses in the 2014-2015 fiscal year of $167 million with revenues of $216 million, growth slowing to 30% for the current year from 74% the prior year. Box has 1200 employees, 45,000 paying customers, and $330 million in cash. Share price has declined by 25%, as it faces strong competition from Amazon, Microsoft, and other larger competitors.

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Ford takes a $2.7 billion charge for Argo startup in driverless cars and says  fully profitable fully autonomous vehicles at scale are a long way off. Ford and VW have each a 40% stake in Argos startup. Ford will now concentrate on partial automated features already offered.

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Toyota's new startup Woven Planet was supposed to create a startup to produce the software that run's cars for today, and do this within a company that produces 10 million cars using tested quality control and factory efficiency methods. It has not worked as shown in this report in WSJ. Deadlines for the software were put off till 2027 and Toyota was falling behind. Toyota had planned a separate city near Mount Fuji for the company and separate cultural setting. This has not happened and Toyota is now integrating the software startup into its own operations bringing forward deadlines to 2025.

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A report in WSJ about misconduct by a former CEO of a software startup.

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This NYT report looks at the gradual breakdown in Silicon Valley of the "fake it till you make it" culture. A vast misallocation of resources by startups and other business, a waste of hundreds of billions of dollars needed for investment in rebuilding the American economy and manufacturing.

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How a tightly interconnected community such as tech startups can quickly fall apart in a crisis is the subject of this WSJ report by Christopher Mims. He says on the way up this meant positive leveraging that exceeded 150% and this is also true in the other direction on the way down just as fast. Most startups depended on Silicon Valley Bank and First Republic for financing. Venture capital moved from inside to unravel the SVB bank. The US government simply wants to stabilize the economy and is not intending to make the uninsured depositors whole except in the way that it is self contained and does not spread to other parts of the banking system. Tech startups will now find it difficult to get new financing, if not impossible, says this report. About 8% of total jobs in the US economy are dependent on tech. When it comes to work that is dependent on tech the number is higher closer to 20%. Some of the tech layoffs will be offset by new kinds of tech and with government private collaboration in the new frameworks coming up, such as for EV vehicles with manufacturing in the US, and the $53 billion for the  CHIPS and Science Act of president Biden. Solar and wind have new frameworks of a similar type as the focus shifts to fighting climate change. These networks are interconnected with the EU which is creating its own parallel networks of this type. ...