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A report by pharmacy benefits managing company Express Scripts shows a 13% increase in the price of branded drugs in the U.S. from Sept 2011 to Sept 2012. Generic drug prices declined by 22% in this period. The report also shows that growing spending on specialty drugs for cancer, MS and other diseases is a big reason for the increase in prices of branded drugs. This report is from a random sample of six millon Express Scripts members using prescription drug coverage. Prof. Schondelmeyer of the University of Minnesota, who manages the drug benefits program at the university and conducts a similiar price report for AARP, says the potential benefits for these specialty drugs are not that good to justify the high prices.

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Current lung cancer screening guidelines and two third of cancer patients at Northwestern Medicine missed 2025.

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Lula and Milei clash at Mercosur. Lula of Brazil talks about a humanitarian crisis in US policy to pressure Venezuela's military installed government but fails to say that a third of Venezuela's population, about 10 million people have left the country as refugees to neighboring countries including Colombia and the US. Inflation at over 100% and mismanagement of the economy have destroyed a once relatively affluent oil producing country in Latin America. Hyperinflation in 2018, and 270% inflation in 2025, and lack of open free elections, lack of food and medicine. A story of socialist ideas that have led to military involvement in politics followed by economic disaster in the western hemisphere, in a country that had a educated middle class and a thriving oil industry. Not since the Spanish opening up Latin America to immigration from Europe by 1600 has the continent of Latin America seen such a mass migration which is not reflected in many media outlets including the NYT, Washington Post and BBC, Guardian. The blockade by the US of oil into and out of Venezuela is affecting Cuba and other countries which depend on this oil. ...

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Marty Makary, John Hopkins surgeon, is the DJT nomnee for head of the US Food and Drug Administration, FDA. Here a colleague of his at John Hopkins offers her experience working with Makary.  Leanna Wen says Makary is concerned about plastics, dyes, preservatives and chemicals that are entering our bodies and causing disease. Diseases that were not so prevalent one or two generations back are widespread today, says Makary. Makary wants to know why. Why has obesity quadrupled among young people in the US?Makary is also asking questions about why rates of childhood obesity are 5 times lower in Japan. Makary tell this Post reporter that ultra processed foods that are loaded with chemicals such as preservatives, artificial dyes and thickeners , take up 60% of calories Americans consume. This and poor food habits of today can cause diabetes, cancer, heart attacks and dementia. Pesticides and microplastics can cause early onset Alzheimer's and autoimmune diseases, attention-deficit/hyperactivity disorders. Makary wants medicine practiced in the US to direct resources to prevention, not simply hand out medicines with increasingly risky side effects. ...

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This report in NHK says contrary to existing ideas American Commodore Perry's ships did not open Japan after pressure to open Japanese ports to the west starting with Nagasaki. It was western medicine and its help in tackling frequent epidemics including smallpox and cholera, that convinced the Japanese of the need to open up their country and learn from the west about science and modern medicine. 

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Chinese turn to traditional medicine as Covid rips through China's population, says this report in the FR24.

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Canada's Ralph Steinmann of the Rockefeller University, New York, wins the Nobel prize in Medicine for his immunity research. The other two winners were Bruce Beutler from the U.S. and Luxembourg's Jules Hoffmann.

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Chris Klomp, 45 years, takes over at 65,000 person $2.6 trillion government agency, Department of Health and Human Services, as Counselor, as Robert Kennedy Jr. heads for the campaign trail in addition to HHS duties March 12 2026. He impressed DJT with his negotiating ability against the drug companies in the government's efforts on Affordability of medicines. DJT calls him "my favorite Mormon." Susie Wiles was looking for a stabilizing force at HHS after vaccine controversies and wants the message to focus on improving health and cutting costs. Robert Kennedy Jr says about Klomp- "He is moving quickly to impose operational discipline, sharpen our strategic direction, and fortify a renewed sense of mission and accountability.” Klomp is pulling together all the agencies under HHS including FDA and others. Klomp takes his role seriously to cut costs and improve Health- .“In health care in particular, I do believe that I’m my brother’s keeper, and our job is to do the very best that we can for the people that we serve — the American people.” ...

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This essay in the WSJ by Louise Aronson, geriatrician, professor of Medicine at UC San Francisco and author of "Elderhood, Redefining Aging, Transforming Medicine, Reimagining Life," and Teva Brender, UC resident in Internal Medicine, says age should not be a factor  in electing leaders, as over the last century life expectancy has grown by 25 to 35 years. People can be healthy into their eighties and modern medicine provides ways to tackle small physical, auditory or visual impairments. In addition these can be handled with strength training, better nutrition and social support, says Aronson. His point is that there has been an increase in "health span" the years we define as being healthy, a compression of morbidity, the disease at the end of life. As a result people can be productive for many years, early retirement is a bad idea economically and for the people themselves when they feel better working. When there is so much wisdom and experience that they can bring to the job, and when that  wisdom and experience is sorely needed by the nation, that guiding light has immense unreplaceable value. President Franklin Roosevelt was at such a time able to steer the nation in the 1930's through the Great Depression and the 1940's through the Second World War, even though he had disabilities. Aronson says the work of elected leaders is fundamentally cognitive and when the basic physical demands can be met it is possible for leaders to work successfully. ...

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J&J, Novartis and Wyeth plan to stop selling cough and cold medicines to infants under the age of 2, just as the FDA is reviewing cases of deaths in the use of these medications by infants.

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This NYT report by Christina Jewett looks at the conflicts of interest when pharmaceutical companies donate to institutions that advise on health policy, to research and technology institutes such as the National Academy of Sciences, Engineering, Medicine. It says the White House and Congress have relied on such scientific advisory groups for policy responses. National Academies is an independent non-governmental institution chartered by Abraham Lincoln in 1863, to serve as an independent adviser to the nation on science and medicine. Here the chief scientist for the University of Colorado Center of Bioethics and Humanities offers his thoughts on the conflict of interest and the damage caused in health policies to the American public.

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Spencer Silver working in 3M labs in Minnesota found a rubbery substance that left no residue and held two surfaces together, It took 10 years before he found a use for it. Most inventing starts accidentally and the use is only found later sometimes taking many years. This is the story of inventing in America and Europe for the last 300 years. This is true for Medicine discoveries happening by accident. It is time for America to return to inventing and investing in its labs and long term research. Efforts which will bring results in improving medicine, health and quality of life. Too much time and resources have been invested in the wrong places for short term results.

 

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A study shown in New England Journal of Medicine shows Pfizer vaccine 2 doses offers 88% protection from symptomatic disease for delta variant of coronavirus. The Astra Zeneca vaccine has 67% protection against delta variant after 2 doses.

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Research at the Perelman School of Medicine at the University of Pennsylvania shows the reduction of serotonin in the gut from coronavirus as a cause of long covid symptoms. This NYT report looks at the research findings.

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Watching Joanna Stern of WSJ interview Sam Altman and Murali Murthi gives the impression that Altman was  moving too quickly and Murthi was saying the right things but lacked the experience and capacity to tackle AI's vast responsibilities. This also stems from the fact that what young Stanford and other tech graduates in their early thirties have done in the last 2 decades ends a chapter in America's tech history. AI is an entirely different technology which requires the involvement of major parts of America's whole technological and scientific community and its society, not just a few individuals. This is also the lesson from the pandemic for virus research where not just the Cambridge, Massachusetts community needed to be involved, but vast parts of America'a health and medicine scientific community and the American public. A million lives were lost in the pandemic in the US alone, and millions all over the world. It is a lesson that should never be forgotten- that technology can get out of control. ...