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Sanger and Gordon point to critical elements of the nuclear deal that were needed but will now be missing. Iranian negotiators now say they will not ship atomic fuel out of the country. For the agreement to be serious and credible about Iran's peaceful intentions for the use of nuclear energy, it was important that the atomic fuel be shipped to Russia, where it would be converted into specialized fuel rods for the Bushehr nuclear power plant. If Iran at some point decided to opt out of the agreement the use of this atomic fuel for peaceful purposes cannot be assured.

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The planned resubmission to the FDA for approval of diabetes drug Tresiba by Novo Nordisk with improved prospects. The Novo team has discussed its findings with regulators. If the resubmission is accepted Tresiba will be ready for launch in 2015 or early 2016. A once weeekly successor to Victoza, injectable treatment for diabetes, and an oral formulation for diabetes, are other new diabetes drugs Novo Nordisk plans to bring out. The oral formulation market is estimated at $13 billion by Citigroup.

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The smartphone market in Brazil is shifting to the $100-$300 range. Because of higher import taxes and other costs, including paying for the full price upfront, buyers pay about $260 for a Moto G whereas a iPhone 6 would cost $1060. The focus is on the better value for the Moto G compared to the Samsung Galaxy and Apple iPhone in developing countries, where new middle class consumers such as in Brazil may make between $5400 to $27,000 a year. This creates opportunities for such phones with superior value- the Moto G has a 5 inch HD display, a 1.2 GHz Qualcomm pocessor, and an 8 megapixel camera. This has helped Lenovo Motorola Mobility take 18% of the Brazil smartphone market, according to IDC, making the Moto G the best selling smartphone in Brazil.

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WSJ Lingling Wei's interview with Ding Xuedong, chairman of China Investment Corporation on its plans and strategies for 2015-2016, and future years. China's government formed CIC in 2007 to improve the returns on its foreign exchange reserves, estimated at $3.8 trillion in 2015. China Investment Corporation had largely stayed with low yields on U.S. Treasury debt till 2007. CIC has about $650 billion in assets in 2015. Its strategies provide insights into how China sees the outlook for the global economy. Ding sees opportunities in real estate and infrastructure, with a focus on the U.S. and Europe for steady cash flows. He singles out the U.S. as of particular interest as its economy rebounds. Strategies also include paring down of energy holdings. Foreign holdings are now $220 billion and have increased by 16.6% since 2009. A special unit CIC Capital was formed recently to more directly participate in managing foreign holdings with a long term view. Earlier focus of CIC on natural resources and commodities is now shifting as the commodities crisis has reduced long term prospects in that sector. The plan for the future is to shift to an allocation where financial products such as stocks and bonds are about 50%, and long term assets such as infrastructure investments, real estate and other investment take up the other 50%. At the end of 2013 equities and fixed income represented 57.4% of CIC global assets, and 28.2% were in long term assets. Ding wants to see China as the No. 2 engine for the global economy after the U.S. as No. 1. He sees the prospects for Brazil, Russia and South Africa as poor, and is optimistic about good performance from India, Mexico and Nigeria. On Japan Ding is skeptical of prime minister Abe's plans because he sees the lack of structural reforms in the efforts leading to a kind of lazy effort in his view. CIC is learning from the experience of other national investment funds and improving its in-house investment and management capabilities. Ding has many years of experience with China's Finance Ministry, the Cabinet, and the State Council. ...

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The U.S supports the creation of a Palestinian state in the United Nations in 2015, as the Obama administration changes UN policies following serious disagreements with Israel on negotiating positions with Palestinian representatives.

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The U.S. effort to protect the sea lanes in the straits of Hormuz as the Iranian backed Houthi rebels advance into the southern port city of Aden in Yemen. This involves support of Saudi airstrikes in Yemen and control of airspace over Yemen. In Iraq the U.S. makes airstrikes to support Iranian backed Shiite militias near Tikrit. The lack of a coherent policy and years of inaction by the Obama administration in the Middle East leads the U.S. into a situation where it is drawn into airstrikes on both sides of the Middle Eastern sectarian Sunni-Shiite conflict.

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The NYT's Adam Nossiter sends this report from Kano, a northern city of 5 million in Nigeria, before the elections for president in Nigeria in March 2015. Nigeria is still divided between the Muslim north and the Christian south. The northeast is facing an insurgency by Boko Haram Muslim militants. The two candidates are the current president, Goodluck Jonathan, a Southern Christian seeking another term, and a former military ruler and northern Muslim, Buhari Muhammad, who is now working within the country's democratic framework. The mood in the country reflects the the lack of essential needs- security lacking in the north with the Boko Haram bombings in Kano and control of areas in the northeast. The Nigerian military has failed to control the Boko Haram insurgency in the northeast. Presidential elections were postponed for six weeks as the Nigerian military grappled with the deteriorating security situation. During this short period South African mercenaries hired by the Nigerian military and the forces of the governments in Chad and Niger which border the area controlled by Boko Haram have pushed the insurgents back, restoring some degree of Nigerian control. The improved security situation benefits the current government. In this report the residents of Kano describe their frustration with the lack of security, electricity, water, and education. Oil revenues have failed to benefit the vast majority of the people of Nigeria, as needs for water, electricity, roads and other infrastructure remain unaddressed six decades after independence....

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Pulliam and Demos look at the murky world of pre IPO trading of shares by venture capital companies and by employees of the pre-IPO companies in the secondary market. Federal and state laws permit pre-IPO trading for unregistered securities. The SEC has not issued more than a couple of enforcement actions for the trading of pre-IPO shares from startup companies. Wealth is now created before an IPO is done. During the 2000 tech boom most of the surge in price happened after the IPO- Amazon's IPO giving the company a valuation of $400 million based on IPO price then, compared to $171 billion in 2015, and Facebook worth $104 billion at the IPO price in 2012, and twice that in 2015. 78 privately held companies are worth over $1 billion in 2015, with combined valuation of $310 billion. The surge in prices of pre-IPO shares comes from the huge demand from investors, who are willing to accept that not much financial information will be disclosed by the startup companies, in the hope of quickly earning a large profit. The estimates of pre-IPO trading for the shares is in the range of $10- $30 billion in shares traded in 2014. This is what the WSJ's Puliam and Demos learned from extensive interviews with traders, investmetn bankers, hedge fund managers, venture capital executives, lawyers and company officials....

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The 28 year old pilot Andreas Lubitz of Lufthansa Germanwings Flight 9525 was being treated for depression at Dusseldorf University Hospital at the time of the flight. Several torn up doctors notes found in his apartment by investigators, including for the day of the flight by his neuropsychologist, show he did not disclose his condition to his employer. Prosecutors say he had intended to "destroy the aircraft" when he flew the plane into France's southern Alps.